Subnatural-Linewidth Polarization-Entangled Photon Pairs with Controllable Temporal Length

We demonstrate an efficient experimental scheme for producing polarization-entangled photon pairs from spontaneous four-wave mixing (SFWM) in a laser-cooled $^{85}$Rb atomic ensemble, with a bandwidth (as low as 0.8 MHz) much narrower than the rubidium atomic natural linewidth. By stabilizing the relative phase between the two SFWM paths in a Mach-Zehnder interferometer configuration, we are able to produce all four Bell states. These subnatural-linewidth photon pairs with polarization entanglement are ideal quantum information carriers for connecting remote atomic quantum nodes via efficient light-matter interaction in a photon-atom quantum network.Comment: Title changed, published version, 5 pages + 3 pages Supplemental Materia

Comparison of the short term therapeutic effects by different incision triple surgery in treating angle-closure glaucoma with cataract

AIM:To compare the therapeutic effects of different incision phacoemulsification with foldable intraocular lens implantation combined with trabeculectomy in treating angle-closure glaucoma complicated with cataract. <p>METHODS: The retrospective study analyzed 70 patients(98 eyes)who performed phacoemulsification with foldable intraocular lens implantation combined with trabeculectomy. Single incision surgery(one-site approach)was performed on 34 patients(50 eyes), and double incision surgery(two-site approaches)was done on 36 patients(48 eyes). The differences of intraocular pressure control,filtering bleb, the density and preservation of corneal endothelium cells both pre-surgery and 1 month post-surgery or later complication. in the two groups were compared and analyzed.Follow-up was 12-24 months with a mean of 18.2 months.<p>RESULTS: The average postoperative intraocular pressure in one-site groups was(10.16±4.31)mmHg. The average postoperative intraocular pressure in two-site groups was(11.38±3.55)mmHg. There were no statistically significant differences between the two groups(<i>P</i>>0.05)regarding the postoperative intraocular pressure and the formation of filtering blebs(<i>P</i>>0.05). The density and area of corneal endothelium cells in the two-incision group pre-operation were comparable(<i>P</i>>0.05). However, in 1 month post-operation, the rate of the corneal endothelial cells loss in double incision group was superior compared to the single incision group(<i>P</i><0.01).<p>CONCLUSION: Both single incision and double incision approach phacotrabeculectomy are effective in reducing intraocular pressure and can maintain the function of filtering blebs well. There are no statistically significant differences in the intraocular pressure reduction between the two approaches. The double incision approach is superior in minimizing the corneal endothelial cells loss compared to the single incision approach

Patient-Derived Induced Pluripotent Stem Cells and Organoids for Modeling Alpha Synuclein Propagation in Parkinson's Disease

Parkinson's disease (PD) is an age-associated, progressive neurodegenerative disorder characterized by motor impairment and in some cases cognitive decline. Central to the disease pathogenesis of PD is a small, presynaptic neuronal protein known as alpha synuclein (a-syn), which tends to accumulate and aggregate in PD brains as Lewy bodies or Lewy neurites. Numerous in vitro and in vivo studies confirm that a-syn aggregates can be propagated from diseased to healthy cells, and it has been suggested that preventing the spread of pathogenic a-syn species can slow PD progression. In this review, we summarize the works of recent literature elucidating mechanisms of a-syn propagation, and discussed the advantages in using patient-derived induced pluripotent stem cells (iPSCs) and/or induced neurons to study a-syn transmission