17,752 research outputs found
Porous zirconia scaffold modified with mesoporous bioglass coating
Porous yttria-stabilized zirconia (YSZ) has been regarded as a potential candidate for bone substitute as its high mechanical strength. However, porous YSZ bodies are biologically inert to bone tissue. It is therefore necessary to introduce bioactive coatings onto the walls of the porous structures to enhance the bioactivity. In this study, the porous zirconia scaffolds were prepared by infiltration of Acrylonitrile Butadiene Styrene (ABS) scaffolds with 3 mol% yttria stabilized zirconia slurry. After sintering, a method of sol-gel dip coating was involved to make coating layer of mesoporous bioglass (MBGs). The porous zirconia without the coating had high porosities of 60.1% to 63.8%, and most macropores were interconnected with pore sizes of 0.5-0.8mm. The porous zirconia had compressive strengths of 9.07-9.90MPa. Moreover, the average coating thickness was about 7μm. There is no significant change of compressive strength for the porous zirconia with mesoporous biogalss coating. The bone marrow stromal cell (BMSC) proliferation test showed both uncoated and coated zirconia scaffolds have good biocompatibility. The scanning electron microscope (SEM) micrographs and the compositional analysis graphs demonstrated that after testing in the simulated body fluid (SBF) for 7 days, the apatite formation occurred on the coating surface. Thus, porous zirconia-based ceramics were modified with bioactive coating of mesoporous bioglass for potential biomedical applications
Structural reliability prediction of a steel bridge element using dynamic object oriented Bayesian Network (DOOBN)
Different from conventional methods for structural reliability evaluation, such as, first/second-order reliability methods (FORM/SORM) or Monte Carlo simulation based on corresponding limit state functions, a novel approach based on dynamic objective oriented Bayesian network (DOOBN) for prediction of structural reliability of a steel bridge element has been proposed in this paper. The DOOBN approach can effectively model the deterioration processes of a steel bridge element and predict their structural reliability over time. This approach is also able to achieve Bayesian updating with observed information from measurements, monitoring and visual inspection. Moreover, the computational capacity embedded in the approach can be used to facilitate integrated management and maintenance optimization in a bridge system. A steel bridge girder is used to validate the proposed approach. The predicted results are compared with those evaluated by FORM method
Practical Block-wise Neural Network Architecture Generation
Convolutional neural networks have gained a remarkable success in computer
vision. However, most usable network architectures are hand-crafted and usually
require expertise and elaborate design. In this paper, we provide a block-wise
network generation pipeline called BlockQNN which automatically builds
high-performance networks using the Q-Learning paradigm with epsilon-greedy
exploration strategy. The optimal network block is constructed by the learning
agent which is trained sequentially to choose component layers. We stack the
block to construct the whole auto-generated network. To accelerate the
generation process, we also propose a distributed asynchronous framework and an
early stop strategy. The block-wise generation brings unique advantages: (1) it
performs competitive results in comparison to the hand-crafted state-of-the-art
networks on image classification, additionally, the best network generated by
BlockQNN achieves 3.54% top-1 error rate on CIFAR-10 which beats all existing
auto-generate networks. (2) in the meanwhile, it offers tremendous reduction of
the search space in designing networks which only spends 3 days with 32 GPUs,
and (3) moreover, it has strong generalizability that the network built on
CIFAR also performs well on a larger-scale ImageNet dataset.Comment: Accepted to CVPR 201
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