2,940 research outputs found
Larval development of Chthamalus malayensis (Cirripedia: Thoracica) reared in the laboratory
Larvae of Chthamalus malayensis (Cirripedia: Thoracica) from Hong Kong were cultured in the laboratory. Larval development includes six naupliar stages and a non-feeding cypris stage. Larvae reached the cypris stage in 20 d at [similar]21°C compared to 14 d at [similar]28°C. Morphological features including the cephalic shield, frontal horns, labrum, abdominal process, antennules, antennae and mandibles in all nauplius and cypris stages were described and illustrated using a combination of light microscopy and scanning electron microscopy. Attempts were made to compare morphological differences between the nauplii and cyprid of C. malayensis with those of other Chthamalus species including C. stellatus, C. montagui, C. dentatus, C. fragilis, C. dalli, C. antennatus, C. fissus and C. challengeri. The present description of the nauplii of C. malayensis is not in agreement with the previous description of this species.published_or_final_versio
Classifying rational densities using two one-dimensional cellular automata
Given a (finite but arbitrarily long) string of zeros and ones, we report a way to determine if the number of ones is less than, greater than, or equal to a prescribed number by applying two sets of cellular automation rules in succession. Thus, we solve the general one-dimensional density classification problem using two cellular automata.published_or_final_versio
Impact of glycaemic control on circulating endothelial progenitor cells and arterial stiffness in patients with type 2 diabetes mellitus
Topics: Basic science, translational and clinical researchPoster PresentationThis journal supplement contains abstracts from the 17th MRC; Dept. of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong KongINTRODUCTION: Patients with type 2 diabetes mellitus (DM) have increased risk of endothelial dysfunction and arterial stiffness. Levels of circulating endothelial progenitor cells (EPCs) are also reduced in hyperglycaemic states. However, the relationships between glycaemic control, levels of EPCs and arterial stiffness are unknown. METHODS: We measured circulating EPCs and …published_or_final_versionThe 17th Medical Research Conference (MRC), Department of Medicine, University of Hong Kong, Hong Kong, 14 January 2012. In Hong Kong Medical Journal, 2012, v. 18 suppl. 1, p. 63, abstract no. 10
Private Federated Learning With Misaligned Power Allocation via Over-the-Air Computation
China Scholarship Council
Over-the-Air Federated Averaging with Limited Power and Privacy Budgets
Part of this work will be presented in IEEE International Conference
on Communications (ICC), 28 May – 01 June 2023, Rome, Italy.This paper develops an optimal design for device scheduling, alignment coefficient, and aggregation rounds within a differentially private over-the-air federated averaging (DP-OTA-FedAvg) system considering a constrained sum power budget. In DP-OTA-FedAvg, gradients are aligned using an alignment coefficient and then aggregated over the air, utilizing channel noise to ensure participant privacy. This study highlights two critical tradeoffs in aligned over-the-air federated learning (OTA-FL) systems with limited power and privacy budgets. Firstly, it reveals the tradeoff between the number of scheduled devices and the alignment coefficient. Secondly, it investigates the balance between aggregation distortion and local training error while adhering to the sum power constraint. Specifically, we measure privacy using differential privacy (DP) and perform convergence analyses for both convex and non-convex loss functions. These analyses provide insights into how device scheduling, the alignment coefficient, and the number of global aggregations affect both privacy preservation and the learning process. Building on these analytical results, we formulate an optimization problem aimed at minimizing the optimality gap of DP-OTA-FedAvg under power and privacy constraints. By specifying the number of aggregation rounds, we derive a closed-form expression describing the relationship between the alignment coefficient and the number of scheduled devices. We then tackle the problem through iterative optimization of scheduling and aggregation rounds. The effectiveness of the proposed policies is verified through simulations, and the performance advantage is particularly pronounced in scenarios where devices have poor channel conditions and limited sum-power budgets
PAHs contamination and bacterial communities in mangrove surface sediments of the Jiulong River Estuary, China
Sixteen sediment samples collected from eight transects in a mangrove swamp of the Jiulong River Estuary, Fujian, China were investigated for their content of polycyclic aromatic hydrocarbons (PAHs) and the biodegradation potential of the indigenous microorganisms. The bacterial community structures in the mangrove sediments and in enrichment cultures were also investigated. The results showed that the total PAHs concentration of mangrove sediments ranged from 280 to 1074 ng g(-1) dry weight, that the PAHs composition pattern in the mangrove sediments was dominated by high molecular weight PAH components (4-6 rings), and that Benzo[ghi]perylene and Indeno[1,2,3-cd]pyrene were the most dominant at different stations. Abundant PAH-degrading bacteria were found in all the stations, the values of phenanthrene-degrading bacteria ranged from 5.85 x 10(4) to 7.80 x 10(5) CFU g(-1) dry weight, fluoranthene-degrading bacteria ranged from 5.25 x 10(4) to 5.79 x 10(5) CFU g(-1) dry weight, pyrene-degrading bacteria ranged from 3.10 x 10(4) to 6.97 x 10(5) CFU g(-1) dry weight and the benzo(a)pyrene-degrading bacteria ranged from 5.25 x 10(4) to 7.26 x 10(5) CFU g(-1) dry weight. DGGE analysis of PCR-amplified 16S rDNA gene fragments confirmed that there was a remarkable shift in the composition of the bacterial community due to the addition of the different model PAH compound phenanthrene (three ring PAH), fluoranthene(four ring PAH), pyrene(four ring PAH) and benzo(a)pyrene(five ring PAH) during enrichment batch culture. Eleven strains were obtained with different morphology and different degradation ability. The presence of common bands for microbial species in the cultures and in the native mangrove sediment DNA indicated that these strains could be potential in situ PAH-degraders. (C) 2008 Elsevier Ltd. All rights reserved
Strain-induced Evolution of Electronic Band Structures in a Twisted Graphene Bilayer
Here we study the evolution of local electronic properties of a twisted
graphene bilayer induced by a strain and a high curvature. The strain and
curvature strongly affect the local band structures of the twisted graphene
bilayer; the energy difference of the two low-energy van Hove singularities
decreases with increasing the lattice deformations and the states condensed
into well-defined pseudo-Landau levels, which mimic the quantization of massive
Dirac fermions in a magnetic field of about 100 T, along a graphene wrinkle.
The joint effect of strain and out-of-plane distortion in the graphene wrinkle
also results in a valley polarization with a significant gap, i.e., the
eight-fold degenerate Landau level at the charge neutrality point is splitted
into two four-fold degenerate quartets polarized on each layer. These results
suggest that strained graphene bilayer could be an ideal platform to realize
the high-temperature zero-field quantum valley Hall effect.Comment: 4 figure
Climate changes reconstructed from a glacial lake in High Central Asiaover the past two millennia
Climatic changes in Arid Central Asia (ACA) over the past two millennia have been widely concerned. However, less attention has been paid to those in the High Central Asia (HCA), where the Asian water tower nurtures the numerous oases by glacier and/or snow melt. Here, we present a new reconstruction of the temperature and precipitation change over the past two millennia based on grain size of a well-dated glacial lake sediment core in the central of southern Tianshan Mountains. The results show that the glacial lake catchment has experienced cold-wet climate conditions during the Dark Age Cold Period (∼300–600 AD; DACP) and the Little Ice Age (∼1300–1870 AD; LIA), whereas warm-dry conditions during the Medieval Warm Period (∼700–1270 AD; MWP). Integration of our results with those of previously published lake sediment records, stalagmite δ18O records, ice core net accumulation rates, tree-ring based temperature reconstructions, and mountain glacier activities suggest that there has a broadly similar hydroclimatic pattern over the HCA areas on centennial time scale during the past two millennia. Comparison between hydroclimatic pattern of the HCA and that of the ACA areas suggests a prevailing 'warm-dry and cold-wet' hydroclimatic pattern over the whole westerlies-dominated central Asia areas during the past two millennia. We argue that the position and intensity of the westerlies, which are closely related to the phase of the North Atlantic Oscillation (NAO), and the strength of the Siberian High pressure (SH), could have jointly modulated the late Holocene central Asia hydroclimatic changes.<br /
Safety of an inactivated, whole-virion COVID-19 vaccine (CoronaVac) in people aged 60 years or older in Hong Kong: a modified self-controlled case series
BACKGROUND:
Because evidence on the safety of COVID-19 vaccines in older adults is scarce, we aimed to evaluate the incidence and risk of adverse events after CoronaVac (Sinovac Biotech) vaccination in adults aged 60 years or older.
METHODS:
In this modified self-controlled case series, we enrolled adults aged 60 years or older who had received at least one dose of CoronaVac in Hong Kong between Feb 23, 2021, and Jan 31, 2022. We extracted population-based, electronic health record data from the clinical management system of the Hospital Authority on adverse events of special interest (from Jan 1, 2005, to Feb 23, 2022) and patients' demographic information (from Jan 1, 2018, to Jan 31, 2022), previous diagnoses (from Jan 1, 2018, to Jan 31, 2022), medication history (from Jan 1, 2018, to Jan 31, 2022), and laboratory tests, including those for SARS-CoV-2 infection (from Jan 1, 2018, to Jan 31, 2022). Details of vaccination status were provided by the Department of Health of the Hong Kong Government and were linked to data from the Hospital Authority with identity card numbers or passport numbers. Our outcomes were the overall incidence of any adverse event of special interest and the incidence rates of 30 adverse events of special interest, as suggested by the WHO Global Advisory Committee on Vaccine Safety, in the inpatient setting within 21 days (2 days for anaphylaxis) of either the first, second, or third CoronaVac dose compared with a baseline period. Individuals who had a history of a particular event between Jan 1, 2005, and Feb 23, 2021, were excluded from the corresponding analysis. We evaluated the risk of an adverse event of special interest using conditional Poisson regression, adjusting for seasonal effects.
FINDINGS:
Of 1 253 497 individuals who received at least one dose of CoronaVac during the study period, 622 317 (49·6%) were aged at least 60 years and were included in the analysis. Our analysis sample received 1 229 423 doses of CoronaVac and had a mean age of 70·40 years (SD 8·10). 293 086 (47·1%) of 622 317 participants were men and 329 231 (52·9%) were women. The incidence of individual adverse events of interest ranged from 0·00 per 100 000 people to 57·49 per 100 000 people (thromboembolism). The first and third doses of CoronaVac were not associated with a significant excess risk of an adverse event of special interest within 21 days (or 2 days for anaphylaxis) of vaccination. After the second dose, the only significantly increased risk was for anaphylaxis (adjusted incidence rate ratio 2·61, 95% CI 1·08–6·31; risk difference per 100 000 people 0·61, 95% CI 0·03–1·81).
INTERPRETATION:
Because older age is associated with poor outcomes after SARS-CoV-2 infection, the benefits of CoronaVac vaccination in older adults outweigh the risks in regions where COVID-19 is prevalent. Ongoing monitoring of vaccine safety is warranted.
FUNDING:
The Food and Health Bureau of the Government, Hong Kong Special Administrative Region, China and AIR@InnoHK, administered by the Innovation and Technology Commission.
TRANSLATION:
For the Chinese translation of the abstract see Supplementary Materials section
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