The use of gis to study the spatial variation of diseases: a case of western region, Ghana

The ability to formulate disease control programmes and put strategic action plans into practice has become an important issue for Regional Health Directorates in Ghana. An important factor in disease control programmes is to correlate variations in different communities with environmental factors using spatially reliable data. To achieve this, spatial distribution maps for predominant diseases such as malaria, skin infection, Respiratory Tract Infection (RTI), asthma and diarrhea for the year 2005 were created. In this study, a database of disease statistics and the geographical information representing the boundaries as well as the centre of the administrative units of the Western Region of Ghana were built using cartographic and GIS techniques – choropleth mapping to examine the spatial distribution of the selected diseases. The results show that there is a strong correlation between mining activities and the prevalence of diseases under study in the Western Region

Ramification of Datum and Ellipsoidal Parameters on Post Processed Differential Global Positioning System (DGPS) Data – A Case Study

The World Geodetic System 1984 (WGS 84) is the global reference frame upon which Global Positioning System (GPS) observations are referenced to. Observations in the frame are in latitudes, longitudes and ellipsoidal heights. For use in a particular locality, it is necessary to convert these into the local coordinate system. In Ghana, the datum and ellipsoidal parameters for Ghana War Office and Clarke 1880 are used for the transformation of the GPS coordinates from the WGS 84 datum system to the Ghana National Grid System. This paper therefore examines post processed DGPS data using these two datum and ellipsoidal definitions separately. Dual frequency DGPS data were collected from 19 survey pillars (ie SGW D224/14/1 to SGW D224/14/19) and post processed using Clarke 1880 datum and ellipsoidal parameters. The raw data was also post processed using Ghana War Office datum and ellipsoidal parameters. The results for the two indicated an average difference of 7.23 m (23.72 ft) for 19 stations. This certainly does not fall within the tolerance set by Survey and Mapping Division (SMD) of the Lands Commission for cadastral plans production, which is +/- 0.9114 m (+/-3 ft). A composite plan using the post processed data from the two datum and ellipsoidal definitions was produced. The plan shows an overlapping area by the use of the two coordinates to plot, an indication of a potential conflict between ownership on paper which may not necessary exist on the ground.Keywords: Differential, Global Positioning System, Datum and Ellipsoidal Parameter

Impact of some savanna trees on soil quality on smallholder farms in a part of Kano, Nigeria

Soil nutrient decline has become a major issue of concern to researchers in the semi-arid region of Nigeria. This condition is further exacerbated by worsening climate and declining environmental quality, amplified by huge population pressure on limited resources. This research investigates the impact of some key savanna tree species on soil quality on smallholder farms in a part of Kano, Nigeria. The results indicate that many indigenous tree species are deliberately left on these smallholder farms in a practice that may be referred to as agroforestry. Inventory of these trees indicates that Vitellaria paradoxa at 25%, Parkia biglobosa at 20%, and Anogeissus leiocarpus at 12%, and Faidherbia albida at 8% are the dominant tree species on smallholder farms in the study area. Laboratory analysis of soil quality at different distances - 2m, 6m and beyond 6m – around the inventoried trees on smallholder farms in the area indicated statistically significant differences in available soil minerals, at 0.02. Eighty-three percent of the farmers corroborated that crops close to trees perform better, in a social survey conducted on some 400 smallholder farmers in the study area. The study recommends: (1) deliberate promotion and regeneration of tree species, most especially leguminous, on smallholder farms; (2) more researches to determine and establish the specific distance(s) at which soil mineral elements are profoundly influenced by trees, and quantifying the actual soil mineral elements that may be made available by each of the different tree species.Keywords: Agroforestry; Indigenous; Savanna; Smallholde

Phytochemical, High Performance Liquid Chromatography and Antimicrobial Evaluations of the Ethanolic Root Extract of Phoenix dactylifera L.

Bioactive compounds from plants have received a great deal of interest from scientists all over the globe for development of drugs. This study was aimed at evaluating phytochemicals, High Performance Liquid Chromatography (HPLC) and antibacterial activities of ethanolic root extract of Phoenix dactylifera L. (date plant) against some clinical isolates. Roots of date plant were dried and extracted with ethanol using the cold maceration method before concentrating it with water bath at 45 oC. The phytochemicals were identified using HPLC based on their individual retention time. Antibacterial activities of the methanolic root extract were assessed against some clinical isolates including Staphylococcus aureus, Klebsiella pneumoniae, Streptococcus pyogenes, and Pseudomonas aeruginosa utilizing agar disc diffusion method. The percentage yield of ethanol extract was 0.3892%. The result of the phytochemical screening revealed the presence of carbohydrate, phenols, tannins, saponins, flavonoids, cardiac glycosides, steroids, alkaloids and terpenes at various retention time of 2.853, 3.235, 4.129, 4.713, 6.722, 8.954, 11.228 and 22.912 min. Compounds identified include phenolic acid (caffeic acid) and two flavonoids (rutin and quercetin). The zone of inhibition diameter ranged from 15 to 19 mm. The maximum zone of inhibition was detected against Streptococcus pyogenes, (19 mm). Staphylococcus aureus and Klebsiella pneumoniae were inhibited with 17 mm and 16 mm zone of inhibition respectively, followed by Pseudomonas aeruginosa which had the least zone of inhibition (15 mm). The result of the present study suggests that the root of Phoenix dactylifera L. possesses important phytochemical components with antibacterial activity that could be possibly exploited for pharmaceutical development

Asymptomatic Giardiasis and Nutritional Status of Children in Two Local Government Areas in Kaduna State, Nigeria

Giardiasis is found throughout the world but more prevalent in developing countries. The present study utilised ELISA coproantigen to determine the prevalence of Giardia lamblia in stool samples of children in day-care centres, nursery and primary schools in two Local Government Areas, Sabon-Gari and Zaria, in Kaduna State, Nigeria. Of 374 samples examined, 150 (41.45%) were positive for Giardia lamblia. The prevalence of giardiasis was higher in males (50.3%) than females (49.7%). There was no significant difference in the level of infection in both sexes (p = 0.808). The highest prevalence of asymptomatic giardiasis was in the age group 3-5 years (32.9%) while the lowest was in the 0-2 years  (11.6%). There was no significant difference in the prevalence of the disease between the age groups (p = 0.414). There was association between asymptomatic giardiasis and wasting (p = 0.030, ANOVA). There was also a positive association between asymptomatic giardiasis and Body Mass Index (p = 0.024, ANOVA) indicating malnutrition. In this study, giardiasis was a predictor of wasting and malnutrition in Sabo-Gari Local Government Area. It is therefore recommended that parents or guardians should provide nutritious meals for school-aged children and treatment of parasitic infections be included in the curriculum of school children

Effects of dietary levels of enzyme (Maxigrain®) supplemented yam peel meal on performance and carcass characteristics of weaner rabbits

A study was carried out to determine the effects of dietary levels of enzyme supplemented yam peel meal (YPM) on performance and carcass characteristics of weaner rabbits. Five diets were formulated using YPM to replace maize at 0%, 25%, 50%, 75% and 100% representing diets 1, 2, 3, 4 and 5 respectively. All the diets were supplemented with Mixagrain® enzyme at 200g except the control diet 1 (0%). Thirty weaner rabbits consisting of mixed breeds and sexes were randomly allotted to the five dietary treatments with six rabbits per treatment and replicated 3 times with 2 rabbits per replicate in a completely randomized design. On the 56th day of the experiment, 3 rabbits from each treatment were randomly selected for carcass and internal organs evaluation. Result of performance shows no significant differences (P>0.05) across the treatments for all the parameters measured for growth performance. Feed cost/kg (₦ /gain) reduces from ₦225.68 in diet 1 – ₦189.15 in diet 5 (100%) while cost savings increased from ₦ 0.9 in diet 1 - ₦28.33 in diet 5 (100%). Result of carcass and internal organs characteristics did not show any significant differences (P>0.05) except for small and large intestine length in diets 4 (75%) and diet 5 (100%). Based on this result therefore, enzyme supplemented YPM can be used to replace maize completely.Keywords: Enzymes, yam peel meal, performance, carcass, weaner rabbit

Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats

Balanites aegyptiaca is a medicinal plant that has been used in a variety of folk medicines in India and Africa for the treatment of different ailments such as syphilis, jaundice, liver and spleen problems, epilepsy, yellow fever. This research aimed at investigating the phyt ochemical constituents, acute toxicity, anti inflammatory and antinociceptive activities of the ethanol extract of Balanites aegyptiaca (EEBA) leaves. The plant material was extracted using ethanol as solvent. The dried ethanol extract was screened for the presence of phytochemicals; Acute toxicity (LD50) was  determined using Lorke’s method while anti inflammatory and antinociceptive activities were evaluated using hot plate and tail immersion methods in albino rats. Results of the study revealed that phyto chemical constituents such as flavonoids, carbohydrates, saponins and glycosides were found in the EEBA, intraperitoneal LD 50 of 2154 mg/kg shows the substance is non toxic. The EEBA produced significant (p <0.05) and dose dependent anti inflammatory and a ntinociceptive activities at all test doses (200, 400 and 600 mg/kg). The presence of the phytochemicals detected might be responsible for the demonstrated anti inflammatory and antinociceptive activities in the plant extract. Keywords: Phytochemical, Anti inflammatory, Antinociceptive , Balanites aegyptiac

Medicinal plants used in the management of diabetes mellitus 2015

Diabetes mellitus is one of the common endocrine disorders prevalent in almost all of the countries. This chronic pathology is characterized by hyperglycemia caused by defective insulin action, insulin secretion, or the combination of both. Prolonged persistence of elevated blood glucose level consequently caused a series of complications such as nephropathy, retinopathy, and cardiomyopathy. Currently available synthetic drugs for treating this disease are found to be associated with many adverse effects. The use of plants in medicine is an age-long practice in various parts of the globe for both preventive and curative purposes. Several warnings have been issued over lack of quality control, scientific evidence for the efficacy, and potential adverse effects of herbal remedies including hepatotoxicity, nephrotoxicity, cardiotoxicity, and reproductive toxicity among others. Despite all of these, reliance on herbs as medicine for the management of diabetes mellitus is still much practiced by a large proportion of the world population because they are readily available and affordable with perceived reduced toxicity. Therefore, with the upsurge of interests in medicinal plants, there is a need for thorough scientific investigations of these plants for both efficacy and potential toxicity. In this issue, we present some recent advances in the use of medicinal plants for treating diabetes mellitus. B. Pang et al. (“Innovative Thoughts of Treating Diabetes from the Perspective of Traditional Chinese Medicine”)presented a review article on the contribution of traditional Chinese medicine to the development of alternative and complementary medicine for the treatment and prevention of diabetes mellitus. In another paper (“Effect of Rhizoma Coptidis (Huang Lian) on Treating Diabetes Mellitus”), B. Pang et al. discussed the efficacy and safety of Rhizoma Coptidis in the treatment of diabetes mellitus. In another study (“Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial”), R. Soltani et al. reported the results of a clinical trial on the effect of Cornus mas L. fruit extract on hyperglycemia in type 2 diabetic patients. In addition, W. Liu et al. (“The Effects of Chinese Medicine on Activation of Wnt/β-Catenin Signal Pathway under High Glucose Condition”) present a valuable review on some compounds implicated in the regulation of Wnt/β-catenin signal pathway as a mechanism of action involved in the antihyperglycemic activity from Chinese medicine. Furthermore, A. O. T. Ashafa and M. I. Kazeem (“Toxicopathological Evaluation of Hydroethanol Extract of Dianthus basuticus in Wistar Rats”) reported on the effects of Dianthus basuticus (a Basotho plant with acclaimed antidiabetic activity) on some biochemical parameters and histology of Wistar rats. Finally, X.-J. Li et al. (“TCM Formula Xiaoyaosan Decoction Improves Depressive-Like Behaviors in Rats with Type 2 Diabetes”) evaluated the effect of traditional medicine formula, Xiaoyaosan, on the cognitive function of diabetic rats. After the first volume of this special issue that was published in 2014, we hope that this issue will present additional valuable information for scientists and clinicians