Method of Estimating the Incompressible-flow Pressure Distribution of Compressor Blade Sections at Design Angle of Attack

A method was devised for estimating the incompressible-flow pressure distribution over compressor blade sections at design angle of attack. The theoretical incremental velocities due to camber and thickness of the section as an isolated airfoil are assumed proportional to the average passage velocity and are modified by empirically determined interference factors. Comparisons were made between estimated and test pressure distributions of NACA 65-series sections for typical conditions. Good agreement was obtained

Measurement of Warfarin in the Oral Fluid of Patients Undergoing Anticoagulant Oral Therapy

BACKGROUND: Patients on warfarin therapy undergo invasive and expensive checks for the coagulability of their blood. No information on coagulation levels is currently available between two controls. METHODOLOGY: A method was developed to determine warfarin in oral fluid by HPLC and fluorimetric detection. The chromatographic separation was performed at room temperature on a C-18 reversed-phase column, 65% PBS and 35% methanol mobile phase, flow rate 0.7 mL/min, injection volume 25 µL, excitation wavelength 310 nm, emission wavelength 400 nm. FINDINGS: The method was free from interference and matrix effect, linear in the range 0.2-100 ng/mL, with a detection limit of 0.2 ng/mL. Its coefficient of variation was <3% for intra-day measurements and <5% for inter-day measurements. The average concentration of warfarin in the oral fluid of 50 patients was 2.5±1.6 ng/mL (range 0.8-7.6 ng/mL). Dosage was not correlated to INR (r = -0.03, p = 0.85) but positively correlated to warfarin concentration in the oral fluid (r = 0.39, p = 0.006). The correlation between warfarin concentration and pH in the oral fluid (r = 0.37, p = 0.009) confirmed the importance of pH in regulating the drug transfer from blood. A correlation between warfarin concentration in the oral fluid and INR was only found in samples with pH values ≥7.2 (r = 0.84, p = 0.004). CONCLUSIONS: Warfarin diffuses from blood to oral fluid. The method allows to measure its concentration in this matrix and to analyze correlations with INR and other parameters

NACA Research Memorandums

"A method was devised for estimating the incompressible-flow pressure distribution over compressor blade sections at design angle of attack. The theoretical incremental velocities due to camber and thickness of the section as an isolated airfoil are assumed proportional to the average passage velocity and are modified by empirically determined interference factors. Comparisons were made between estimated and test pressure distributions of NACA 65-series sections for typical conditions. Good agreement was obtained" (p. 1)

NACA Research Memorandums

Report presenting a method to estimate the incompressible-flow surface pressures of compressor airfoils in cascade at design angle of attack by modifying the known pressure distribution as an isolated airfoil. The interference between airfoils was found to vary in a systematic manner. Testing performed on NACA 65-series compressor blade sections appears to agree with estimated values