103,714 research outputs found
Optical properties of Si/Si0.87Ge0.13 multiple quantum well wires
Nanometer-scale wires cut into a Si/Si0.87Ge0.13 multiple quantum well structure were fabricated and characterized by using photoluminescence and photoreflectance at temperatures between 4 and 20 K. It was found that, in addition to a low-energy broadband emission at around 0.8 eV and other features normally observable in photoluminescence measurements, fabrication process induced strain relaxation and enhanced electron-hole droplets emission together with a new feature at 1.131 eV at 4 K were observed. The latter was further identified as a transition related to impurities located at the Si/Si0.87Ge0.13 heterointerfaces
XXVI IUPAP Conference on Computational Physics (CCP2014)
The 26th IUPAP Conference on Computational Physics, CCP2014, was held in Boston, Massachusetts, during August 11-14, 2014. Almost 400 participants from 38 countries convened at the George Sherman Union at Boston University for four days of plenary and parallel sessions spanning a broad range of topics in computational physics and related areas.
The first meeting in the series that developed into the annual Conference on Computational Physics (CCP) was held in 1989, also on the campus of Boston University and chaired by our colleague Claudio Rebbi. The express purpose of that meeting was to discuss the progress, opportunities and challenges of common interest to physicists engaged in computational research. The conference having returned to the site of its inception, it is interesting to recect on the development of the field during the intervening years. Though 25 years is a short time for mankind, computational physics has taken giant leaps during these years, not only because of the enormous increases in computer power but especially because of the development of new methods and algorithms, and the growing awareness of the opportunities the new technologies and methods can offer. Computational physics now represents a ''third leg'' of research alongside analytical theory and experiments in almost all subfields of physics, and because of this there is also increasing specialization within the community of computational physicists. It is therefore a challenge to organize a meeting such as CCP, which must have suffcient depth in different areas to hold the interest of experts while at the same time being broad and accessible. Still, at a time when computational research continues to gain in importance, the CCP series is critical in the way it fosters cross-fertilization among fields, with many participants specifically attending in order to get exposure to new methods in fields outside their own.
As organizers and editors of these Proceedings, we are very pleased with the high quality of the papers provided by the participants. These articles represent a good cross-section of what was presented at the meeting, and it is our hope that they will not only be useful individually for their specific scientific content but will also represent a historical snapshot of the state of computational physics that they represent collectively.
The remainder of this Preface contains lists detailing the organizational structure of CCP2014, endorsers and sponsors of the meeting, plenary and invited talks, and a presentation of the 2014 IUPAP C20 Young Scientist Prize.
We would like to take the opportunity to again thank all those who contributed to the success of CCP214, as organizers, sponsors, presenters, exhibitors, and participants.
Anders Sandvik, David Campbell, David Coker, Ying TangPublished versio
Signal Transduction Pathways in the Pentameric Ligand-Gated Ion Channels
The mechanisms of allosteric action within pentameric ligand-gated ion channels (pLGICs) remain to be determined. Using crystallography, site-directed mutagenesis, and two-electrode voltage clamp measurements, we identified two functionally relevant sites in the extracellular (EC) domain of the bacterial pLGIC from Gloeobacter violaceus (GLIC). One site is at the C-loop region, where the NQN mutation (D91N, E177Q, and D178N) eliminated inter-subunit salt bridges in the open-channel GLIC structure and thereby shifted the channel activation to a higher agonist concentration. The other site is below the C-loop, where binding of the anesthetic ketamine inhibited GLIC currents in a concentration dependent manner. To understand how a perturbation signal in the EC domain, either resulting from the NQN mutation or ketamine binding, is transduced to the channel gate, we have used the Perturbation-based Markovian Transmission (PMT) model to determine dynamic responses of the GLIC channel and signaling pathways upon initial perturbations in the EC domain of GLIC. Despite the existence of many possible routes for the initial perturbation signal to reach the channel gate, the PMT model in combination with Yen's algorithm revealed that perturbation signals with the highest probability flow travel either via the β1-β2 loop or through pre-TM1. The β1-β2 loop occurs in either intra- or inter-subunit pathways, while pre-TM1 occurs exclusively in inter-subunit pathways. Residues involved in both types of pathways are well supported by previous experimental data on nAChR. The direct coupling between pre-TM1 and TM2 of the adjacent subunit adds new insight into the allosteric signaling mechanism in pLGICs. © 2013 Mowrey et al
New quaternary sequences of even length with optimal auto-correlation
Sequences with low auto-correlation property have been applied in
code-division multiple access communication systems, radar and cryptography.
Using the inverse Gray mapping, a quaternary sequence of even length can be
obtained from two binary sequences of the same length, which are called
component sequences. In this paper, using interleaving method, we present
several classes of component sequences from twin-prime sequences pairs or GMW
sequences pairs given by Tang and Ding in 2010; two, three or four binary
sequences defined by cyclotomic classes of order . Hence we can obtain new
classes of quaternary sequences, which are different from known ones, since
known component sequences are constructed from a pair of binary sequences with
optimal auto-correlation or Sidel'nikov sequences.Comment: This paper was submitted to Science China: Information Sciences at
Oct 16, 2016, and accpted for publication at Apr 27, 201
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