3,211 research outputs found
Application of biasing-potential replica exchange simulations for loop modeling and refinement of proteins in explicit solvent
Laser diagnostics for characterization of sprays formed by a collapsing non-equilibrium bubble
In this paper, we investigate the use of laser diagnostic tools for in-plane imaging
of bubble induced spray using a laser sheet and Mie scattering technique. A perspex plate of
thickness 10 mm with a hole of diameter 1 mm in the center is placed in the middle of a glass
tank filled with water such that the top surface of the plate coincides with the water surface.
A bubble is created just below the hole using a low-voltage spark circuit such that it expands
against the hole. This leads to the formation of two jets which impact leading to a spray and
break-up into droplets. The spray evolution is observed using a laser sheet directed in a plane
through the center of the hole. The illuminated plane is imaged using a high-speed camera
based on the Mie scattering from glass beads suspended in the liquid. Results show that Mie
scattering technique has potential in studying bubble-induced sprays with applications such as
in fuel sprays, drug-delivery etc, and also for validation of numerical codes. We present results
from our ongoing experiments in this paper
Effect of native Trichoderma viride and Pseudomonas fluorescens on the development of Cuscuta campestris on chickpea, Cicer arietinum
Cuscuta campestris Yuncker is a serious parasite on several leguminous crops including chickpea in India. Chickpea is an important pulse crop in India and severe incidence of Cuscuta may result in yield loss of about 85.7%. Management of Cuscuta is very difficult because of their intricate relationship with the host, wide host range and lack of resistant genes in the host. Thus induced systemic resistance (ISR) by plant growth promoting microbes (microbial elicitors) may be an effective alternative method for the management of Cuscuta. In the current study, to induce systemic resistance, native isolates of Trichoderma viride Pers. and Pseudomonas fluorescens Flügge were used as seed treatments and foliar spray on chickpea and then infested with C. campestris. Salicylic acid and thiobenzamidazole (synthetic elicitors) were used as standard inducing agents for comparison. Results indicated that fresh seeds of C. campestris germinated rapidly even without scarification and that the germination was not influenced by the proximity of the seeds to the host. Seed treatment followed by foliar sprays with the bioagents and synthetic elicitors induced at 20 and 40 days after sowing (DAS) induced increased production of defense enzymes in chickpea (Cicer arietinum L.) and thus delayed the development (1.8-5 days) and flowering (2.4-4.2 days) of C. campestris. Treatment with both the elicitors also resulted in the enhanced activities of scavengers of enzymes related reactive oxygen species (ROS). Thus the above work would help in the integration of the application of bioagents for effective management of Cuscuta in chickpea
Analysis of ISO 26262 Compliant Techniques for the Automotive Domain
The ISO 26262 standard denes functional safety for automotive E/E systems. Since the publication of the rst edition of this standard in 2011, many dierent safety techniques complying to the ISO 26262 have been developed. However, it is not clear which parts and (sub-) phases of the standard are targeted by these techniques and which objectives of the standard are particularly addressed. Therefore, we carried out a gap analysis to identify gaps between the safety standard objectives of the part 3 till 7 and the existing techniques. In this paper the results of the gap analysis are presented such as we identied that there is a lack of mature tool support for the ASIL sub-phase and a need for a common platform for the entire product development cycle
Analysis of ISO 26262 Compliant Techniques for the Automotive Domain
The ISO 26262 standard denes functional safety for automotive E/E systems. Since the publication of the rst edition of this standard in 2011, many dierent safety techniques complying to the ISO 26262 have been developed. However, it is not clear which parts and (sub-) phases of the standard are targeted by these techniques and which objectives of the standard are particularly addressed. Therefore, we carried out a gap analysis to identify gaps between the safety standard objectives of the part 3 till 7 and the existing techniques. In this paper the results of the gap analysis are presented such as we identied that there is a lack of mature tool support for the ASIL sub-phase and a need for a common platform for the entire product development cycle
Incorporating Forcing Terms in Cascaded Lattice-Boltzmann Approach by Method of Central Moments
Cascaded lattice-Boltzmann method (Cascaded-LBM) employs a new class of
collision operators aiming to improve numerical stability. It achieves this and
distinguishes from other collision operators, such as in the standard single or
multiple relaxation time approaches, by performing relaxation process due to
collisions in terms of moments shifted by the local hydrodynamic fluid
velocity, i.e. central moments, in an ascending order-by-order at different
relaxation rates. In this paper, we propose and derive source terms in the
Cascaded-LBM to represent the effect of external or internal forces on the
dynamics of fluid motion. This is essentially achieved by matching the
continuous form of the central moments of the source or forcing terms with its
discrete version. Different forms of continuous central moments of sources,
including one that is obtained from a local Maxwellian, are considered in this
regard. As a result, the forcing terms obtained in this new formulation are
Galilean invariant by construction. The method of central moments along with
the associated orthogonal properties of the moment basis completely determines
the expressions for the source terms as a function of the force and macroscopic
velocity fields. In contrast to the existing forcing schemes, it is found that
they involve higher order terms in velocity space. It is shown that the
proposed approach implies "generalization" of both local equilibrium and source
terms in the usual lattice frame of reference, which depend on the ratio of the
relaxation times of moments of different orders. An analysis by means of the
Chapman-Enskog multiscale expansion shows that the Cascaded-LBM with forcing
terms is consistent with the Navier-Stokes equations. Computational experiments
with canonical problems involving different types of forces demonstrate its
accuracy.Comment: 55 pages, 4 figure
Optimal Principal Component Analysis in Distributed and Streaming Models
We study the Principal Component Analysis (PCA) problem in the distributed
and streaming models of computation. Given a matrix a
rank parameter , and an accuracy parameter , we
want to output an orthonormal matrix for which where is the best rank- approximation to .
This paper provides improved algorithms for distributed PCA and streaming
PCA.Comment: STOC2016 full versio
Analysis of Barthel index and care giver strain index in stroke patients in tertiary care hospital in South India
Background: Stroke patients have high rate of mortality and morbidity and survivors suffer from physical, cognitive and emotional issues. Quality of life of stroke survivors depends on severity of disability. These disability or morbidities not only affect stroke survivors but also has impact on physical and psychological wellbeing of caregivers providing support for daily routine. Aim of this study is to analyse the dependency using Barthel Index in stroke patients and care giver strain (CSI) among caregivers.
Methods: A cross sectional descriptive study in a tertiary care hospital in South India. Study duration of 5 months. 150 Patients admitted for stroke meeting the inclusion criteria were included for the study. Caregiver was interviewed after Informed consent and briefing of purpose of study. Berthel index and modified care giver strain index questionnaire was filled by interviewer with caregiver. Findings were described in simple descriptive manner. Statistical package for the social sciences (SPSS) version 24 was used for statistical analysis.
Results: Of 150 patients male 64% female 36%. Care giver strain score of <7 (40%), 8-14 (42%), >14 (18%). Sleep deprivation 68%, physical strain 85%, family adjustment problems 32%, work adjustment problems 67%, financial strain 76%, emotional adjustment problems 33%, personal plans problems 44%, upsetting behavior problems 44%. Only 17% termed it as inconvenient, 24% completely overwhelmed, 29% confining. Barthel index of >80 able to live independently (13%), 61-80 minimally dependent (32%), 41-60 partially dependent (26%), 21-40 very dependent (13%), <20 total dependency (16%).
Conclusions: In stroke care caregiver strain is high when patient is dependent for routine activities. This includes physical as well as psychological strain. There is need to develop strategic home based or community based programs to reduce caregiver stress and improve their quality of life
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