136 research outputs found

    Direct-write diffracting tubular optical components using femtosecond lasers

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    Over the last decade, femtosecond lasers have been used extensively for the fabrication of optical elements via direct writing and in combination with chemical etching. These processes have been an enabling technology for manufacturing a variety of devices such as waveguides, fluidic channels, and mechanical components. Here, we present high quality micro-scale optical components buried inside various glass substrates such as soda-lime glass or fused silica. These components consist of high-precision, simple patterns with tubular shapes. Typical diameters range from a few microns to one hundred microns. With the aid of high-bandwidth, high acceleration flexure stages, we achieve highly symmetric pattern geometries, which are particularly important for achieving homogeneous stress distribution within the substrate. We model the optical properties of these structures using beam propagation simulation techniques and experimentally demonstrate that such components can be used as cost-effective, low-numerical aperture lenses. Additionally, we investigate their capability for studying the stress-distribution induced by the laser-affected zones and possible related densification effects

    Arbitrary optical retardance patterns generated in bulk silica glass by laser-written stressors

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    We present micro-scale stressors written in bulk silica using an ultrafast laser. Stress from nanograting formation produces optical retardance, which is then tailored through control of the orientation, magnitude, and anisotropy of the stress field

    Beyond conventional 3D ultrafast laser material processing

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    Material processing with ultrafast lasers has attracted considerable interest due to a wide range of applications from laser surgery and integrated optics to optical data storage, 3D micro- and nano-structuring [1,2]. A decade ago it has been discovered that under certain irradiation conditions ordered sub-wavelength structures with features smaller than 20 nm can be formed in the volume of silica glass [3]. The effect of nanograting formation has attracted considerable interest with proposals of applications ranging from nanofluidics [4,5] to polarization control devices [6]

    Investigating femtosecond laser interaction with tellurite glass family

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    Focusing ultrafast laser pulses induce localized permanent structural modifications on the surface or in transparent materials, that are of particular interest for photonic applications. Among the materials of interest, the tellurite glass family is attractive for near-infrared and photonics applications due to its broad-transparency window and high optical nonlinearity. Here, we systematically investigate structural changes occurring in various TeO2-based glasses exposed to femtosecond laser with various laser parameters. Remarkably, in a regime where heat accumulated after successive pulses, we observed the formation of polarization-controlled self-organized patterns expanding well beyond the focal volume, suggesting the presence of an evanescent coupling mechanism enhancing the self-organization. In addition, our results, obtained with compositional elemental analysis coupled with Raman spectra suggest different ion migration mechanisms in the laser affected zone at the surface and inside the glass. The formation of crystalline tellurium (t-Te) from glass structural units due to photo-induced elemental dissociation was observed only at the surface. The formation of ultrathin layer of crystalline tellurium offers the possibility to explore structural transitions in two-dimensional (2D) glasses by observing changes in the short- and medium- range structural orders, induced by spatial confinement

    A monolithic micro-tensile tester for investigating silica micromechanics, fabricated and fully operated using a femtosecond laser Citation for published version (APA)

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    . (2014). A monolithic micro-tensile tester for investigating silica micromechanics, fabricated and fully operated using a femtosecond laser

    Antiferromagnetic ordering in a 90 K copper oxide superconductor

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    Using elastic neutron scattering, we evidence a commensurate antiferromagnetic Cu(2) order (AF) in the superconducting (SC) high-Tc\rm T_c cuprate YBa2(Cu1yCoy)3O7+δ\rm YBa_2(Cu_{1-y}Co_y)_3O_{7+\delta} (y=0.013, Tc\rm T_c=93 K). As in the Co-free system, the spin excitation spectrum is dominated by a magnetic resonance peak at 41 meV but with a reduced spectral weight. The substitution of Co thus leads to a state where AF and SC cohabit showing that the CuO2_2 plane is a highly antiferromagnetically polarizable medium even for a sample where Tc_c remains optimum.Comment: 3 figure

    Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

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    We obtained unanticipated synthetic byproducts from alkylation of the δ[superscript 1] nitrogen (N3) of the histidine imidazole ring of the polo-like kinase-1 (Plk1) polo-box domain (PBD)-binding peptide PLHSpT. For the highest-affinity byproduct, bearing a C[subscript 6]H[subscript 5](CH[subscript 2])[subscript 8]– group, a Plk1 PBD cocrystal structure revealed a new binding channel that had previously been occluded. An N-terminal PEGylated version of this peptide containing a hydrolytically stable phosphothreonyl residue (pT) bound the Plk1 PBD with affinity equal to that of the non-PEGylated parent but showed markedly less interaction with the PBDs of the two closely related proteins Plk2 and Plk3. Treatment of cultured cells with this PEGylated peptide resulted in delocalization of Plk1 from centrosomes and kinetochores and in chromosome misalignment that effectively induced mitotic block and apoptotic cell death. This work provides insights that might advance efforts to develop Plk1 PBD-binding inhibitors as potential Plk1-specific anticancer agents.National Institutes of Health (U.S.) (Grant GM60594)National Institutes of Health (U.S.) (Grant GM68762)National Institutes of Health (U.S.) (Grant CA112967

    Ultrafast laser micro-nano structuring of transparent materials with high aspect ratio

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    Ultrafast lasers are ideal tools to process transparent materials because they spatially confine the deposition of laser energy within the material's bulk via nonlinear photoionization processes. Nonlinear propagation and filamentation were initially regarded as deleterious effects. But in the last decade, they turned out to be benefits to control energy deposition over long distances. These effects create very high aspect ratio structures which have found a number of important applications, particularly for glass separation with non-ablative techniques. This chapter reviews the developments of in-volume ultrafast laser processing of transparent materials. We discuss the basic physics of the processes, characterization means, filamentation of Gaussian and Bessel beams and provide an overview of present applications
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