Drosophila Chitinase 2 is expressed in chitin producing organs for cuticle formation.

The architecture of the outer body wall cuticle is fundamental to protect arthropods against invading pathogens and numerous other harmful stresses. Such robust cuticles are formed by parallel running chitin microfibrils. Molting and also local wounding leads to dynamic assembly and disassembly of the chitin-matrix throughout development. However, the underlying molecular mechanisms that organize proper chitin-matrix formation are poorly known. Recently we identified a key region for cuticle thickening at the apical cell surface, the cuticle assembly zone, where Obstructor-A (Obst-A) coordinates the formation of the chitin-matrix. Obst-A binds chitin and the deacetylase Serpentine (Serp) in a core complex, which is required for chitin-matrix maturation and preservation. Here we present evidence that Chitinase 2 (Cht2) could be essential for this molecular machinery. We show that Cht2 is expressed in the chitin-matrix of epidermis, trachea, and the digestive system. There, Cht2 is enriched at the apical cell surface and the dense chitin-matrix. We further show that in Cht2 knockdown larvae the assembly zone is rudimentary, preventing normal cuticle formation and pore canal organization. As sequence similarities of Cht2 and the core complex proteins indicate evolutionarily conserved molecular mechanisms, our findings suggest that Cht2 is involved in chitin formation also in other insects

Whirling Hexagons and Defect Chaos in Hexagonal Non-Boussinesq Convection

We study hexagon patterns in non-Boussinesq convection of a thin rotating layer of water. For realistic parameters and boundary conditions we identify various linear instabilities of the pattern. We focus on the dynamics arising from an oscillatory side-band instability that leads to a spatially disordered chaotic state characterized by oscillating (whirling) hexagons. Using triangulation we obtain the distribution functions for the number of pentagonal and heptagonal convection cells. In contrast to the results found for defect chaos in the complex Ginzburg-Landau equation and in inclined-layer convection, the distribution functions can show deviations from a squared Poisson distribution that suggest non-trivial correlations between the defects.Comment: 4 mpg-movies are available at http://www.esam.northwestern.edu/~riecke/lit/lit.html submitted to New J. Physic

Specific heat and thermal conductivity in the vortex state of the two-gap superconductor MgB_2

The specific heat coefficient gamma_s(H) and the electronic thermal conductivity kappa_{es}(H) are calculated for Abrikosov's vortex lattice by taking into account the effects of supercurrent flow and Andreev scattering. First we solve the gap equation for the entire range of magnetic fields. We take into account vertex corrections due to impurity scattering calculated in the Born approximation. The function gamma_s(H)/gamma_n increases from zero and becomes approximately linear above H/H_{c2} \sim 0.1. The dependence on impurity scattering is substantially reduced by the vertex corrections. The upward curvature of kappa_{es}(H)/kappa_{en}, which is caused by decreasing Andreev scattering for increasing field, is reduced for increasing impurity scattering. We also calculate the temperature dependence of the scattering rates 1/tau_{ps}(H) of a phonon and 1/tau_{es}(H) of a quasiparticle due to quasiparticle and phonon scattering, respectively. At low temperatures the ratio tau_{pn}/tau_{ps}(H) increases rapidly to one as H tends to H_{c2} which yields a rapid drop in the phononic thermal conductivity kappa_{ph}. Our results are in qualitative agreement with the experiments on the two-gap superconductor MgB_2.Comment: 12 pages, 5 figures, additions to figures 1, 2, and 3. Accepted by Phys. Rev.

ss- and dxyd_{xy}-wave components induced around a vortex in dx2−y2d_{x^2-y^2}-wave superconductors

Vortex structure of $d_{x^2-y^2}$-wave superconductors is microscopically analyzed in the framework of the quasi-classical Eilenberger equations. If the pairing interaction contains an $s$-wave ($d_{xy}$-wave) component in addition to a $d_{x^2-y^2}$-wave component, the $s$-wave ($d_{xy}$-wave) component of the order parameter is necessarily induced around a vortex in $d_{x^2-y^2}$-wave superconductors. The spatial distribution of the induced $s$-wave and $d_{xy}$-wave components is calculated. The $s$-wave component has opposite winding number around vortex near the $d_{x^2-y^2}$-vortex core and its amplitude has the shape of a four-lobe clover. The amplitude of $d_{xy}$-component has the shape of an octofoil. These are consistent with results based on the GL theory.Comment: RevTex,9 pages, 6 figures in a uuencoded fil

Ultrasonic attenuation in magnetic fields for superconducting states with line nodes in Sr2RuO4

We calculate the ultrasonic attenuation in magnetic fields for superconducting states with line nodes vertical or horizontal relative to the RuO_2 planes. This theory, which is valid for fields near Hc2 and not too low temperatures, takes into account the effects of supercurrent flow and Andreev scattering by the Abrikosov vortex lattice. For rotating in-plane field H(theta) the attenuation alpha(theta)exhibits variations of fourfold symmetry in the rotation angle theta. In the case of vertical nodes, the transverse T100 sound mode yields the weakest(linear)H and T dependence of alpha, while the longitudinal L100 mode yields a stronger (quadratic) H and T dependence. This is in strong contrast to the case of horizontal line nodes where alpha is the same for the T100 and L100 modes (apart from a shift of pi/4 in field direction) and is roughly a quadratic function of H and T. Thus we conclude that measurements of alpha in in-plane magnetic fields for different in-plane sound modes may be an important tool for probing the nodal structure of the gap in Sr_2RuO_4.Comment: 5 pages, 6 figures, replaced in non-preprint form, to appear in Phys. Rev.

Vortex structure in chiral p-wave superconductors

We investigate the vortex structure in chiral p-wave superconductors by the Bogoliubov-de Gennes theory on a tight-binding model. We calculate the spatial structure of the pair potential and electronic state around a vortex, including the anisotropy of the Fermi surface and superconducting gap structure. The differences of the vortex structure between $\sin p_x + {\rm i} \sin p_y$-wave and $\sin p_x - {\rm i} \sin p_y$-wave superconductors are clarified in the vortex lattice state. We also discuss the winding $\mp 3$ case of the $\sin{(p_x+p_y)} \pm {\rm i} \sin{(-p_x+p_y)}$-wave superconductivity.Comment: 10 pages, 8 figure

Experimentation with a dynamic pricing approach for hotel industry

A dynamic pricing approach for hotel revenue management is suggested. It aims at increasing revenue over the baseline

Vortex structure in dd-wave superconductors

Vortex structure of pure $d_{x^2-y^2}$-wave superconductors is microscopically analyzed in the framework of the quasi-classical Eilenberger equations. Selfconsistent solution for the $d$-wave pair potential is obtained for the first time in the case of an isolated vortex. The vortex core structure, i.e., the pair potential, the supercurrent and the magnetic field, is found to be fourfold symmetric even in the case that the mixing of $s$-wave component is absent. The detailed temperature dependences of these quantities are calculated. The fourfold symmetry becomes clear when temperature is decreased. The local density of states is calculated for the selfconsistently obtained pair potential. From the results, we discuss the flow trajectory of the quasiparticles around a vortex, which is characteristic in the $d_{x^2-y^2}$-wave superconductors. The experimental relevance of our results to high temperature superconductors is also given.Comment: 22 pages, RevTex, 23 figures available upon reques

Dynamic pricing with demand disaggregation for hotel revenue management

In this paper we present a novel approach to the dynamic pricing problem for hotel businesses. It includes disaggregation of the demand into several categories, forecasting, elastic demand simulation, and a mathematical programming model with concave quadratic objective function and linear constraints for dynamic price optimization. The approach is computationally efficient and easy to implement. In computer experiments with a hotel data set, the hotel revenue is increased by about 6% on average in comparison with the actual revenue gained in a past period, where the fixed price policy was employed, subject to an assumption that the demand can deviate from the suggested elastic model. The approach and the developed software can be a useful tool for small hotels recovering from the economic consequences of the COVID-19 pandemic

Impurity Effect on Kramer-Pesch Core Shrinkage in s-Wave Vortex and Chiral p-Wave Vortex

The low-temperature shrinking of the vortex core (Kramer-Pesch effect) is studied for an isolated single vortex for chiral p-wave and s-wave superconducting phases. The effect of nonmagnetic impurities on the vortex core radius is numerically investigated in the Born limit by means of a quasiclassical approach. It is shown that in the chiral p-wave phase the Kramer-Pesch effect displays a certain robustness against impurities owing to a specific quantum effect, while the s-wave phase reacts more sensitively to impurity scattering. This suggests chiral p-wave superconductors as promising candidates for the experimental observation of the Kramer-Pesch effect.Comment: 18 pages, 4 figures; to be published in J. Low Temp. Phys.; Proc. of NATO ARW: VORTEX 2004, Yalta (Uknaine