195 research outputs found

    Igneous clasts in the Northwest Africa 801 CR2 chondrite: REE and oxygen isotopic studies.

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    第3回極域科学シンポジウム/第35回南極隕石シンポジウム 11月30日(金) 国立国語研究所 2階講

    Spin-phonon coupled modes in the incommensurate phases of doped CuGeO3_{3}

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    The doping effect of the folded phonon mode at 98 cm−1^{-1} was investigated on the Si-doped CuGeO3_3 by magneto-optical measurements in far-infrared (FIR) region under high magnetic field. The folded phonon mode at 98 cm−1^{-1} appears not only in the dimerized (D) phase but also in the dimerized-anitiferromagnetic (DAF) phase on the doped CuGeO3_3. The splitting was observed in the incommensurate (IC) phase and the antiferromagnetically ordered incommensurate (IAF) phase above HCH_C. The split-off branches exhibit different field dependence from that of the pure CuGeO3_3 in the vicinity of HCH_C, and the discrepancy in the IAF phase is larger than that in the IC phase. It is caused by the interaction between the solitons and the impurities.Comment: 7 pages, 4 figures, resubmitted to Phys. Rev.

    Energy Dissipation Burst on the Traffic Congestion

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    We introduce an energy dissipation model for traffic flow based on the optimal velocity model (OV model). In this model, vehicles are defined as moving under the rule of the OV model, and energy dissipation rate is defined as the product of the velocity of a vehicle and resistant force which works to it.Comment: 15 pages, 19 Postscript figures. Reason for replacing: This is the submitted for

    Magnetic and Dielectric Properties in Multiferroic Cu3Mo2O9 under High Magnetic Fields

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    The magnetic and dielectric properties under high magnetic fields are studied in the single crystal of Cu3Mo2O9. This multiferroic compound has distorted tetrahedral spin chains. The effects of the quasi-one dimensionality and the geometrical spin frustration are expected to appear simultaneously. We measure the magnetoelectric current and the differential magnetization under the pulsed magnetic field up to 74 T. We also measure the electric polarization versus the electric field curve/loop under the static field up to 23 T. Dielectric properties change at the magnetic fields where the magnetization jumps are observed in the magnetization curve. Moreover, the magnetization plateaus are found at high magnetic fields.Comment: 6 pages, 3 figures, in press in JPS Conf. Proc. as a part of SCES2013 Proceeding

    Possible Phase Transition Deep Inside the Hidden Order Phase of Ultraclean URu2Si2

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    To elucidate the underlying nature of the hidden order (HO) state in heavy-fermion compound URu2Si2, we measure electrical transport properties of ultraclean crystals in a high field/low temperature regime. Unlike previous studies, the present system with much less impurity scattering resolves a distinct anomaly of the Hall resistivity at H*=22.5 T well below the destruction field of the HO phase ~36 T. In addition, a novel quantum oscillation appears above a magnetic field slightly below H*. These results indicate an abrupt reconstruction of the Fermi surface, which implies a possible phase transition well within the HO phase caused by a band-dependent destruction of the HO parameter. The present results definitely indicate that the HO transition should be described by an itinerant electron picture.Comment: 4 pages, 4 figures, accepted for publication in Physical Review Letter

    Low energy excitations and dynamic Dzyaloshinskii-Moriya interaction in α′\alpha'-NaV2_2O5_5 studied by far infrared spectroscopy

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    We have studied far infrared transmission spectra of alpha'-NaV2O5 between 3 and 200cm-1 in polarizations of incident light parallel to a, b, and c crystallographic axes in magnetic fields up to 33T. The triplet origin of an excitation at 65.4cm-1 is revealed by splitting in the magnetic field. The magnitude of the spin gap at low temperatures is found to be magnetic field independent at least up to 33T. All other infrared-active transitions appearing below Tc are ascribed to zone-folded phonons. Two different dynamic Dzyaloshinskii-Moriya (DM) mechanisms have been discovered that contribute to the oscillator strength of the otherwise forbidden singlet to triplet transition. 1. The strongest singlet to triplet transition is an electric dipole transition where the polarization of the incident light's electric field is parallel to the ladder rungs, and is allowed by the dynamic DM interaction created by a high frequency optical a-axis phonon. 2. In the incident light polarization perpendicular to the ladder planes an enhancement of the singlet to triplet transition is observed when the applied magnetic field shifts the singlet to triplet resonance frequency to match the 68cm-1 c-axis phonon energy. The origin of this mechanism is the dynamic DM interaction created by the 68cm-1 c-axis optical phonon. The strength of the dynamic DM is calculated for both mechanisms using the presented theory.Comment: 21 pages, 22 figures. Version 2 with replaced fig. 18 were labels had been los

    Cross-species chromosome painting tracks the independent origin of multiple sex chromosomes in two cofamiliar Erythrinidae fishes

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    <p>Abstract</p> <p>Background</p> <p>The Erythrinidae fish family is characterized by a large variation with respect to diploid chromosome numbers and sex-determining systems among its species, including two multiple X<sub>1</sub>X<sub>2</sub>Y sex systems in <it>Hoplias malabaricus </it>and <it>Erythrinus erythrinus</it>. At first, the occurrence of a same sex chromosome system within a family suggests that the sex chromosomes are correlated and originated from ancestral XY chromosomes that were either homomorphic or at an early stage of differentiation. To identify the origin and evolution of these X<sub>1</sub>X<sub>2</sub>Y sex chromosomes, we performed reciprocal cross-species FISH experiments with two sex-chromosome-specific probes designed from microdissected X<sub>1 </sub>and Y chromosomes of <it>H. malabaricus </it>and <it>E. erythrinus</it>, respectively.</p> <p>Results</p> <p>Our results yield valuable information regarding the origin and evolution of these sex chromosome systems. Our data indicate that these sex chromosomes evolved independently in these two closed related Erythrinidae species. Different autosomes were first converted into a poorly differentiated XY sex pair in each species, and additional chromosomal rearrangements produced both X<sub>1</sub>X<sub>2</sub>Y sex systems that are currently present.</p> <p>Conclusions</p> <p>Our data provide new insights into the origin and evolution of sex chromosomes, which increases our knowledge about fish sex chromosome evolution.</p

    Drosophila growth-blocking peptide-like factor mediates acute immune reactions during infectious and non-infectious stress

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    Antimicrobial peptides (AMPs), major innate immune effectors, are induced to protect hosts against invading microorganisms. AMPs are also induced under non-infectious stress; however, the signaling pathways of non-infectious stress-induced AMP expression are yet unclear. We demonstrated that growth-blocking peptide (GBP) is a potent cytokine that regulates stressor-induced AMP expression in insects. GBP overexpression in Drosophila elevated expression of AMPs. GBP-induced AMP expression did not require Toll and immune deficiency (Imd) pathway-related genes, but imd and basket were essential, indicating that GBP signaling in Drosophila did not use the orthodox Toll or Imd pathway but used the JNK pathway after association with the adaptor protein Imd. The enhancement of AMP expression by non-infectious physical or environmental stressors was apparent in controls but not in GBP-knockdown larvae. These results indicate that the Drosophila GBP signaling pathway mediates acute innate immune reactions under various stresses, regardless of whether they are infectious or non-infectious

    Turnover of Sex Chromosomes in the Stickleback Fishes (Gasterosteidae)

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    Diverse sex-chromosome systems are found in vertebrates, particularly in teleost fishes, where different systems can be found in closely related species. Several mechanisms have been proposed for the rapid turnover of sex chromosomes, including the transposition of an existing sex-determination gene, the appearance of a new sex-determination gene on an autosome, and fusions between sex chromosomes and autosomes. To better understand these evolutionary transitions, a detailed comparison of sex chromosomes between closely related species is essential. Here, we used genetic mapping and molecular cytogenetics to characterize the sex-chromosome systems of multiple stickleback species (Gasterosteidae). Previously, we demonstrated that male threespine stickleback fish (Gasterosteus aculeatus) have a heteromorphic XY pair corresponding to linkage group (LG) 19. In this study, we found that the ninespine stickleback (Pungitius pungitius) has a heteromorphic XY pair corresponding to LG12. In black-spotted stickleback (G. wheatlandi) males, one copy of LG12 has fused to the LG19-derived Y chromosome, giving rise to an X1X2Y sex-determination system. In contrast, neither LG12 nor LG19 is linked to sex in two other species: the brook stickleback (Culaea inconstans) and the fourspine stickleback (Apeltes quadracus). However, we confirmed the existence of a previously reported heteromorphic ZW sex-chromosome pair in the fourspine stickleback. The sex-chromosome diversity that we have uncovered in sticklebacks provides a rich comparative resource for understanding the mechanisms that underlie the rapid turnover of sex-chromosome systems

    Epidermal growth factor receptor structural alterations in gastric cancer

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    <p>Abstract</p> <p>Background</p> <p>EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well as gene amplification were associated with a good clinical response to EGFR inhibitors. In gastric tumours data concerning structural alterations of EGFR remains controversial. Given its possible therapeutic relevance, we aimed to determine the frequency and type of structural alterations of the <it>EGFR </it>gene in a series of primary gastric carcinomas.</p> <p>Methods</p> <p>Direct sequencing of the kinase domain of the <it>EGFR </it>gene was performed in a series of 77 primary gastric carcinomas. FISH analysis was performed in 30 cases. Association studies between <it>EGFR </it>alterations and the clinical pathological features of the tumours were performed.</p> <p>Results</p> <p>Within the 77 primary gastric carcinomas we found two <it>EGFR </it>somatic mutations and several <it>EGFR </it>polymorphisms in exon 20. Six different intronic sequence variants of <it>EGFR </it>were also found. Four gastric carcinomas showed balanced polysomy or <it>EGFR </it>gene amplification. We verified that gastric carcinoma with alterations of <it>EGFR </it>(somatic mutations or copy number variation) showed a significant increase of tumour size (<it>p </it>= 0.0094) in comparison to wild-type <it>EGFR </it>carcinomas.</p> <p>Conclusion</p> <p>We demonstrate that <it>EGFR </it>structural alterations are rare in gastric carcinoma, but whenever present, it leads to tumour growth. We considered that searching for <it>EGFR </it>alterations in gastric cancer is likely to be clinically important in order to identify patients susceptible to respond to tyrosine kinase inhibitors.</p
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