3,209 research outputs found
Stacked Dual-Wavelength Near-Infrared Organic Photodetectors
Organic near-infrared (NIR) detectors have potential applications in biomedicine, agriculture, and manufacturing industries to identify and quantify materials contactless, in real time and at a low cost. Recently, tunable narrow-band NIR sensors based on charge-transfer state absorption of bulk-heterojunctions embedded into Fabry-Pérot micro-cavities have been demonstrated. In this work, this type of sensor is further miniaturized by stacking two sub-cavities on top of each other. The resulting three-terminal device detects and distinguishes photons at two specific wavelengths. By varying the thickness of each sub-cavity, the detection ranges of the two sub-sensors are tuned independently between 790 and 1180, and 1020 and 1435 nm, respectively, with full-width-at-half-maxima ranging between 35 and 61 nm. Transfer matrix modeling is employed to select and optimize device architectures with a suppressed cross-talk in the coupled resonator system formed by the sub-cavities, and thus to allow for two distinct resonances. These stacked photodetectors pave the way for highly integrated, bi-signal spectroscopy tunable over a broad NIR range. To demonstrate the application potential, the stacked dual sensor is used to determine the ethanol concentration in a water solution
Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia. The aims of the present study were to localize platelet sequestration in the pulmonary microcirculation and to investigate the role of P-selectin as a molecular mechanism of platelet endothelial cell interaction. Methods: We used in vivo fluorescence microscopy to quantify the kinetics of fluorescently labeled erythrocytes and platelets in alveolar capillary networks in rabbit lungs. Results: Six hours after onset of endotoxin infusion we observed a massive rolling along and firm adherence of platelets to lung capillary endothelial cells whereas under control conditions no platelet sequestration was detected. P-selectin was expressed on the surface of separated platelets which were incubated with endotoxin and in lung tissue. Pretreatment of platelets with fucoidin, a P-selectin antagonist, significantly attenuated the endotoxin-induced platelet rolling and adherence. In contrast, intravenous infusion of fucoidin in endotoxin-treated rabbits did not inhibit platelet sequestration in pulmonary capillaries. Conclusion: We conclude that platelets accumulate in alveolar capillaries following endotoxemia. P-selectin expressed on the surface of platelets seems to play an important role in mediating this platelet-endothelial cell interaction. Copyright (c) 2006 S. Karger AG, Basel
Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection
Planarians have long been studied for their regenerative abilities. Moving forward, tools for ectopic expression of non-native proteins will be of substantial value. Using a luminescent reporter to overcome the strong autofluorescence of planarian tissues, we demonstrate heterologous protein expression in planarian cells and live animals. Our approach is based on the introduction of mRNA through several nanotechnological and chemical transfection methods. We improve reporter expression by altering untranslated region (UTR) sequences and codon bias, facilitating the measurement of expression kinetics in both isolated cells and whole planarians using luminescence imaging. We also examine protein expression as a function of variations in the UTRs of delivered mRNA, demonstrating a framework to investigate gene regulation at the post-transcriptional level. Together, these advances expand the toolbox for the mechanistic analysis of planarian biology and establish a foundation for the development and expansion of transgenic techniques in this unique model system
Avalanche amplification of a single exciton in a semiconductor nanowire
Interfacing single photons and electrons is a crucial ingredient for sharing
quantum information between remote solid-state qubits. Semiconductor nanowires
offer the unique possibility to combine optical quantum dots with avalanche
photodiodes, thus enabling the conversion of an incoming single photon into a
macroscopic current for efficient electrical detection. Currently, millions of
excitation events are required to perform electrical read-out of an exciton
qubit state. Here we demonstrate multiplication of carriers from only a single
exciton generated in a quantum dot after tunneling into a nanowire avalanche
photodiode. Due to the large amplification of both electrons and holes (>
10^4), we reduce by four orders of magnitude the number of excitation events
required to electrically detect a single exciton generated in a quantum dot.
This work represents a significant step towards single-shot electrical read-out
and offers a new functionality for on-chip quantum information circuits
Single Spin Asymmetries of Inclusive Hadrons Produced in Electron Scattering from a Transversely Polarized He Target
We report the first measurement of target single-spin asymmetries (A) in
the inclusive hadron production reaction,
+, using a transversely polarized
He target. The experiment was conducted at Jefferson Lab in Hall A using a
5.9-GeV electron beam. Three types of hadrons (,
and proton) were detected in the transverse hadron momentum range 0.54
0.74 GeV/c. The range of for pions was -0.29 -0.23 and for kaons
-0.25 -0.18. The observed asymmetry strongly depends on the type of
hadron. A positive asymmetry is observed for and . A
negative asymmetry is observed for . The magnitudes of the asymmetries
follow . The K and proton
asymmetries are consistent with zero within the experimental uncertainties. The
and asymmetries measured for the He target and
extracted for neutrons are opposite in sign with a small increase observed as a
function of .Comment: Updated version, submitted to Phys. Rev.
Double Spin Asymmetries of Inclusive Hadron Electroproductions from a Transversely Polarized Target
We report the measurement of beam-target double-spin asymmetries
() in the inclusive production of identified hadrons,
+, using a longitudinally
polarized 5.9 GeV electron beam and a transversely polarized
target. Hadrons (, and proton) were detected at
16 with an average momentum =2.35 GeV/c and a transverse
momentum () coverage from 0.60 to 0.68 GeV/c. Asymmetries from the
target were observed to be non-zero for production
when the target was polarized transversely in the horizontal plane. The
and asymmetries have opposite signs, analogous to the
behavior of in semi-inclusive deep-inelastic scattering.Comment: Published in PRC (92.015207), nuclear experiment, high-energy
experimen
Single Spin Asymmetries in Charged Kaon Production from Semi-Inclusive Deep Inelastic Scattering on a Transversely Polarized Target
We report the first measurement of target single spin asymmetries of charged
kaons produced in semi-inclusive deep inelastic scattering of electrons off a
transversely polarized target. Both the Collins and Sivers
moments, which are related to the nucleon transversity and Sivers
distributions, respectively, are extracted over the kinematic range of
0.10.4 for and production. While the Collins and
Sivers moments for are consistent with zero within the experimental
uncertainties, both moments for favor negative values. The Sivers
moments are compared to the theoretical prediction from a phenomenological fit
to the world data. While the Sivers moments are consistent with the
prediction, the results differ from the prediction at the 2-sigma
level.Comment: 6 pages, 3 figure
Measurement of pretzelosity asymmetry of charged pion production in Semi-Inclusive Deep Inelastic Scattering on a polarized He target
An experiment to measure single-spin asymmetries in semi-inclusive production
of charged pions in deep-inelastic scattering on a transversely polarized
He target was performed at Jefferson Lab in the kinematic region of
and . The pretzelosity asymmetries on
He, which can be expressed as the convolution of the
transverse momentum dependent distribution functions and the Collins
fragmentation functions in the leading order, were measured for the first time.
Using the effective polarization approximation, we extracted the corresponding
neutron asymmetries from the measured He asymmetries and cross-section
ratios between the proton and He. Our results show that for both
on He and on the neutron the pretzelosity asymmetries are
consistent with zero within experimental uncertainties.Comment: 6 pages, 3 figures; enlarged the legends in Fig.3; added 3 citation
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