50 research outputs found
A new technique of bladder neck reconstruction during radical prostatectomy in patients with prostate cancer
Robotic surgery: disruptive innovation or unfulfilled promise? A systematic review and meta-analysis of the first 30 years
805 Effect of chronic inflammation of the prostate on ratio of free-to-total prostate specific antigen in serum
S177: Laparoscopic radical nephrectomy in patients with renal vein invasion: Our initial experience
Comparison of the factors affecting the durability of flexible ureterorenoscope for renal stone therapy retrospectively
394 Role of Positron Emission Tomography/Computed Tomography (PET/CT) in the evaluation of the metastatic adrenal masses
The relationship between microscopic hematuria and bladder cancer: Are currently available diagnostic methods reliable? [Mikroskopik hematüri ile mesane kanserinin ilişkisi: Bugün için kullanilan tani yöntemleri güvenilir mi?]
Objective: This study aimed to evaluate the sensitivity and specificity of radiological diagnostic methods, urinary biomarkers and urine cytology for patients with microscopic hematuria in the diagnosis of bladder cancer. Materials and methods: A total of 150 patients with the initial diagnosis of microscopic hematuria were included in the study. Patients were prospectively evaluated in terms of urinary symptomatology, physical examination, smoking habits, intravenous pyelography (IVP), abdominal ultrasonography (USG), Nuclear Matrix Protein 22 (NMP22), urine cytology and NMP22 BladderChek® test. The cut-off point for NMP22 test was accepted as 10 U/mL. Results: Mean age of the study population was 49.8±10.79 years with a male to female ratio of 1.08 (78/72). Overall, 10.7% (n=16) of patients had pathological diagnosis of bladder cancer, whereas 89.5% of the study population had no etiology for microhematuria. IVP was considered as the most sensitive and specific test in the diagnosis of bladder cancer. However, voided urine cytology was the least sensitive test, although it has the same specificity with IVP. The best sensitivity and specificity values were demonstrated when NMP22 and abdominal USG were used in double-test combinations. Conclusion: In microscopic hematuria, the combination of radiological methods with tumor markers such as NMP22 BladderChek® test, provides 100% sensitivity, and protects nearly half of cases from unnecessary cystoscopies