1,757 research outputs found
Critical phenomena in globally coupled excitable elements
Critical phenomena in globally coupled excitable elements are studied by
focusing on a saddle-node bifurcation at the collective level. Critical
exponents that characterize divergent fluctuations of interspike intervals near
the bifurcation are calculated theoretically. The calculated values appear to
be in good agreement with those determined by numerical experiments. The
relevance of our results to jamming transitions is also mentioned.Comment: 4 pages, 3 figure
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Interrater reliability in visual identification of interictal high-frequency oscillations on electrocorticography and scalp EEG.
High-frequency oscillations (HFOs), including ripples (Rs) and fast ripples (FRs), are promising biomarkers of epileptogenesis, but their clinical utility is limited by the lack of a standardized approach to identification. We set out to determine whether electroencephalographers experienced in HFO analysis can reliably identify and quantify interictal HFOs. Two blinded raters independently reviewed 10 intraoperative electrocorticography (ECoG) samples from epilepsy surgery cases, and 10 scalp EEG samples from epilepsy monitoring unit evaluations. HFOs were visually marked using bandpass filters (R, 80-250 Hz; FR, 250-500 Hz) with a sampling frequency of 2,000 Hz. There was agreement as to the presence or absence of epileptiform discharges (EDs), Rs, and FRs, in 17, 18, and 18 cases, respectively. Interrater reliability (IRR) was favorable with κ = 0.70, 0.80, and 0.80, respectively, and similar for ECoG and scalp electroencephalography (EEG). Furthermore, interclass correlation for rates of Rs (0.99, 95% confidence interval [CI] 0.96-0.99) and FRs (0.77, 95% CI 0.41-0.91) were superior in comparison to EDs (0.37, 95% CI -0.60 to 0.75). Our data suggest that HFO identification and quantification are reliable among experienced electroencephalographers. Our findings support the reliability of utilizing HFO data in both research and clinical arenas
Flow pattern transition accompanied with sudden growth of flow resistance in two-dimensional curvilinear viscoelastic flows
We find three types of steady solutions and remarkable flow pattern
transitions between them in a two-dimensional wavy-walled channel for low to
moderate Reynolds (Re) and Weissenberg (Wi) numbers using direct numerical
simulations with spectral element method. The solutions are called
"convective", "transition", and "elastic" in ascending order of Wi. In the
convective region in the Re-Wi parameter space, the convective effect and the
pressure gradient balance on average. As Wi increases, the elastic effect
becomes suddenly comparable and the first transition sets in. Through the
transition, a separation vortex disappears and a jet flow induced close to the
wall by the viscoelasticity moves into the bulk; The viscous drag significantly
drops and the elastic wall friction rises sharply. This transition is caused by
an elastic force in the streamwise direction due to the competition of the
convective and elastic effects. In the transition region, the convective and
elastic effects balance. When the elastic effect dominates the convective
effect, the second transition occurs but it is relatively moderate. The second
one seems to be governed by so-called Weissenberg effect. These transitions are
not sensitive to driving forces. By the scaling analysis, it is shown that the
stress component is proportional to the Reynolds number on the boundary of the
first transition in the Re-Wi space. This scaling coincides well with the
numerical result.Comment: 33pages, 23figures, submitted to Physical Review
The X10 Flare on 2003 October 29: Triggered by Magnetic Reconnection between Counter-Helical Fluxes?
Vector magnetograms taken at Huairou Solar Observing Station (HSOS) and Mees
Solar Observatory (MSO) reveal that the super active region (AR) NOAA 10486 was
a complex region containing current helicity flux of opposite signs. The main
positive sunspots were dominated by negative helicity fields, while positive
helicity patches persisted both inside and around the main positive sunspots.
Based on a comparison of two days of deduced current helicity density,
pronounced changes were noticed which were associated with the occurrence of an
X10 flare that peaked at 20:49 UT, 2003 October 29. The average current
helicity density (negative) of the main sunspots decreased significantly by
about 50. Accordingly, the helicity densities of counter-helical patches
(positive) were also found to decay by the same proportion or more. In
addition, two hard X-ray (HXR) `footpoints' were observed by the Reuven Ramaty
High Energy Solar Spectroscopic Imager (RHESSI} during the flare in the 50-100
keV energy range. The cores of these two HXR footpoints were adjacent to the
positions of two patches with positive current helicity which disappeared after
the flare. This strongly suggested that the X10 flare on 2003 Oct. 29 resulted
from reconnection between magnetic flux tubes having opposite current helicity.
Finally, the global decrease of current helicity in AR 10486 by ~50% can be
understood as the helicity launched away by the halo coronal mass ejection
(CME) associated with the X10 flare.Comment: Solar Physics, 2007, in pres
Synergistic Formation of Radicals by Irradiation with Both Vacuum Ultraviolet and Atomic Hydrogen: A Real-Time In Situ Electron Spin Resonance Study
We report on the surface modification of polytetrafluoroethylene (PTFE) as an
example of soft- and bio-materials that occur under plasma discharge by
kinetics analysis of radical formation using in situ real-time electron spin
resonance (ESR) measurements. During irradiation with hydrogen plasma,
simultaneous measurements of the gas-phase ESR signals of atomic hydrogen and
the carbon dangling bond (C-DB) on PTFE were performed. Dynamic changes of the
C-DB density were observed in real time, where the rate of density change was
accelerated during initial irradiation and then became constant over time. It
is noteworthy that C-DBs were formed synergistically by irradiation with both
vacuum ultraviolet (VUV) and atomic hydrogen. The in situ real-time ESR
technique is useful to elucidate synergistic roles during plasma surface
modification.Comment: 14 pages, 4 figure
Frodo Links Dishevelled to the p120-Catenin/Kaiso Pathway: Distinct Catenin Subfamilies Promote Wnt Signals
Summaryp120-catenin is an Arm repeat protein that interacts with varied components such as cadherin, small G proteins, kinases, and the Kaiso transcriptional repressor. Despite recent advances in understanding the roles that p120-catenin and Kaiso play in downstream modulation of Wnt/β-catenin signaling, the identity of the upstream regulators of the p120-catenin/Kaiso pathway have remained unclear. Here, we find that p120-catenin binds Frodo, which itself interacts with the Wnt pathway protein Dishevelled (Dsh). In Xenopus laevis, we demonstrate that Wnt signals result in Frodo-mediated stabilization of p120-catenin, which, in turn, promotes Kaiso sequestration or removal from the nucleus. Our results point to Dsh and Frodo as upstream regulators of the p120-catenin/Kaiso signaling pathway. Importantly, this suggests that Wnt signals acting through Dsh regulate the stability of p120-catenin in addition to that of β-catenin, and that each catenin promotes its respective signal in parallel to regulate distinct, as well as shared, direct downstream gene targets
Local density of states around a magnetic impurity in high-Tc superconductors based on the t-J model
The local density of states (LDOS) around a magnetic impurity in high-Tc
superconductors is studied using the two-dimensional t-J model with a realistic
band structure. The order parameters are determined in a self-consistent way
within the Gutzwiller approximation and the Bogoliubov-de Gennes theory. In
sharp contrast with the nonmagnetic impurity case, the LDOS near the magnetic
impurity shows two resonance peaks reflecting the presence of spin-dependent
resonance states. It is also shown that these resonance states are
approximately localized around the impurity. The present results have an large
implication on the scanning tunneling spectroscopy observation of
Bi_{2}Sr_{2}Ca(Cu_{1-x}Ni[Zn]_{x})_{2}O_{8+delta}.Comment: 4 pages, 3 figures, to appear in Phys. Rev. Let
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