Role of Latissimus Dorsi Island Flap in Coverage of Mutilating Upper Limb Injuries in Pediatric Age Group

Background/Purpose: Latissimus dorsi muscle (LDM) is one of the most versatile muscles that is commonly used in different reconstructive procedures. Severe mutilating injuries of the upper limb in children represent a great challenge to reconstructive surgeons especially when important structures become exposed. Materials & Methods: we utilized LDM as an island flap to cover extensive soft tissue defects in the upper limb of pediatric patients. This work included 17 children (13 males and 4 females). All of them had extensive soft tissue loss of the upper limb with exposure of important structures. The cause of injury was road traffic accident in all patients. We analyzed the operative time, need for multi-stage surgery and the recorded complications. Finally, we recorded the ultimate functional and aesthetic outcome after a period of two years of follow up. Results: From the harvested seventeen flaps, none of them was lost. Split thickness skin graft was done one week after flap harvesting and insetting to cover the muscle flap. There were four cases with partial loss of the skin graft secondary to infection. Those four cases needed re-grafting after eradication of infection that needed almost two weeks of local wound care and dressing. Re-grafting was successful in the four cases. Conclusion: For complex upper extremity wounds in the pediatric age group, we advice aggressive debridement and early reconstruction with LDM pedicle flap with a split-thickness skin graft cover over it. The technique is reliable, with minimal donor site morbidity and very accepted functional and cosmetic outcome.Index Word: Latissimus dorsi muscle flap, complex trauma, pediatric age group

Challenges of Internet of Things and Big Data Integration

The Internet of Things anticipates the conjunction of physical gadgets to the In-ternet and their access to wireless sensor data which makes it expedient to restrain the physical world. Big Data convergence has put multifarious new opportunities ahead of business ventures to get into a new market or enhance their operations in the current market. considering the existing techniques and technologies, it is probably safe to say that the best solution is to use big data tools to provide an analytical solution to the Internet of Things. Based on the current technology deployment and adoption trends, it is envisioned that the Internet of Things is the technology of the future, while to-day's real-world devices can provide real and valuable analytics, and people in the real world use many IoT devices. Despite all the advertisements that companies offer in connection with the Internet of Things, you as a liable consumer, have the right to be suspicious about IoT advertise-ments. The primary question is: What is the promise of the Internet of things con-cerning reality and what are the prospects for the future.Comment: Proceedings of the International Conference on International Conference on Emerging Technologies in Computing 2018 (iCETiC '18), 23rd -24th August, 2018, at London Metropolitan University, London, UK, Published by Springer-Verla

Bounds Testing Approaches to the Analysis of Long-run Relationships

This paper This paper develops a new approach to the problem of testing the existence of a long-run level relationship between a dependent variable and a set of regressors, when it is not known with certainty whether the underlying regressors are trend- or first-difference stationary. The proposed tests are based on standard F- and t-statistics used to test the significance of the lagged levels of the variables in a first-difference regression. Two sets of asymptotic critical values are provided: one set assuming that all the regressors are I(1) and another set assuming they are all I(0). These two sets of critical values provide a band covering all possible classifications of the regressors into I(0), I(1) or mutually cointegrated. Accordingly, various bounds testing procedures are proposed. The empirical relevance of the bounds procedures is demonstrated by a re-examination of the earnings equation included in the UK Treasury macro-econometric model. This is a particularly relevant application as there is considerable doubt concerning the order of integration of variables such as the unemployment rate, union strength and the wedge between the real product wage' and the real consumption wage' that enter the earnings equationLong-run relationship, Unrestricted error correction model, Cointegration, Unit roots, Bounds tests

Heterogeneous Signcryption Scheme with Group Equality Test for Satellite-enabled IoVs

With the growing popularization of the Internet of Vehicles (IoVs), the combination of satellite navigation system and IoVs is also in a state of continuous improvement. In this paper, we present a heterogeneous signcryption scheme with group equality test for IoVs (HSC-GET), which avoids the adversaries existing in the insecure channels to intercept, alter or delete messages from satellite to vehicles. The satellite is arranged in an identity-based cryptographic (IBC) system to ensure safe and fast transmission of instruction, while the vehicles are arranged in certificateless cryptosystem (CLC) to concern the security of the equipment. In addition, the group granularity authorization is integrated to ensure the cloud server can only execute the equality test on ciphertext generated by the same group of vehicles. Through rigorous performance and security analyses, we observe that our proposed construction reduces the equality test overhead by about 63:96%, 81:23%, 80:84%, and 54:98% in comparison to other competitive protocols. Furthermore, the confidentiality, integrity and authenticity of messages are guaranteed

Visualizing the transfer-messenger RNA as the ribosome resumes translation

Bacterial ribosomes that are stalled on mRNAs lacking a stop codon can be rescued by a process called ‘transtranslation' that involves the ribonucleoprotein complex tmRNA–SmpB. This cryo-EM study, and the copublished study by Weis et al, reveal how translation on tmRNA is resume

Dizajniranje i sinteza novih derivata tiofenkarbohidrazida, tienopirazola i tienopirimidina s antioksidativnim i antitumorskim djelovanjem

2-Amino-5-acetyl-4-methyl-thiophene-3-carboxylic acid ethyl ester (1) and 5-acetyl-2-amino-4-methylthiophene-3-carbohydrazide (2) were synthesized and used as starting materials for the synthesis of new series of 1-(5-amino-4-(3,5-dimethyl-1H-pyrazole-1-carbonyl)-3-methylthiophen-2-yl) ethanone (3a), 1-(5-amino-4-(4-chloro-3,5-dimethyl-1H-pyrazole-1-carbonyl)-3-methylthiophen-2-yl) ethanone (3b), 1-(4-methyl-2-amino-5-acetylthiophene-3-carbonyl) pyrazolidine-3,5-dione (4), (Z)-N\u27-(4-methyl-2-amino-5-acetylthiophene-3-carbonyl) formohydrazonic acid (5a), (Z)-ethyl-N\u27-(4-methyl-2-amino-5-acetylthiophene-3-carbonylformo hydrazonate (5b), 6-acetyl-3-amino-2,5-dimethylthieno2,3-dpyrimidin-4(3H)-one (8), 5-methyl-3-amino-2-mercapto-6-acetylthieno2,3-dpyrimidin-4(3H)-one (10) and 5-methyl-6-acetyl-2-thioxo-2,3-dihydrothieno2,3-dpyrimidin-4(1H)-one (12) as potential antioxidant and antitumor agents. Pharmacological results showed that compounds 6a, 6b, 8, 10 and 12 exhibited promising antitumor and antioxidant activity.Etilni ester 2-amino-5-acetil-4-metil-tiofen-3-karboksilne kiseline (1) i 5-acetil-2-amino-4-metiltiofen-3-karbohidrazid (2) sintetizirani su i upotrebljeni kao reaktanti u sintezi novih spojeva 1-(5-amino-4-(3,5-dimetil-1H-pirazol-1-karbonil)-3-metiltiofen-2-il) etanona (3a), 1-(5-amino-4-(4-klor-3,5-dimetil-1H-pirazol-1-karbonil)-3-metiltiofen-2-il) etanona (3b), 1-(4-metil-2-amino-5-acetiltiofen-3-karbonil) pirazolidin-3,5-diona (4), (Z)-N\u27-(4-metil-2-amino-5-acetiltiofen-3-karbonil) formohidrazonske kiseline (5a), (Z)-etil-N\u27-(4-metil-2-amino-5-acetiltiofen-3-karbonilformo hidrazonata (5b), 6-acetil-3-amino-2,5-dimetiltieno2,3-dpirimidin-4(3H)-one (8), 5-metil-3-amino-2-merkapto-6-acetiltieno2,3-dpirimidin-4(3H)-ona (10) i 5-metil-6-acetil-2-tiokso-2,3-dihidrotieno2,3-dpirimidin-4(1H)-ona (12) kao potencijalnih antioksidansa i citostatika. Farmakološka ispitivanja ukazuju na to da spojevi 6a, 6b, 8, 10 i 12 imaju značajno antitumorsko i antioksidativno djelovanje

Effects of Foliar Nutrition on Onion Seed Storage under Modified Atmosphere Packages

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Effects of Foliar Nutrition on Onion Seed Storage under Controlled Atmosphere

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Foliar Nutrition and Post-Harvest of Onion Seed: effects of storage temperatures, storage period and foliar nutrition

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