Statistical parametric map showing the significant differences in the ALFF between three groups: depressed PD patients, non-depressed PD patients and NCs.

<p>A) The differences between depressed PD patients and non-depressed PD patients. B) The differences between non-depressed PD patients and NCs. C) The differences between depressed PD patients and NCs. The threshold for display was set to p<0.005, cluster size> = 432 mm³.</p

Clinical and demographic characteristics.

<p>Note: Abbreviations: HY–Hoehn and Yahr; UPDRS–Unified Parkinson’s Disease Rating Scale; MMSE–Mini Mental state examination.</p

Brain regions exhibiting an altered ALFF between depressed PD patients and non-depressed PD patients.

<p>BA: Brodmann area; MNI: Montreal neurological institute.</p

Brain regions exhibiting an altered ALFF between non-depressed PD patients and NCs.

<p>BA: Brodmann area; MNI: Montreal neurological institute; SMA: supplementary motor area.</p