Rh(III)-Catalyzed Decarboxylative <i>ortho</i>-Heteroarylation of Aromatic Carboxylic Acids by Using the Carboxylic Acid as a Traceless Directing Group

Highly selective decarboxylative <i>ortho</i>-heteroarylation of aromatic carboxylic acids with various heteroarenes has been developed through Rh­(III)-catalyzed two-fold C–H activation, which exhibits a wide substrate scope of both aromatic carboxylic acids and heteroarenes. The use of naturally occurring carboxylic acid as the directing group avoids troublesome extra steps for installation and removal of an external directing group

Copper(II)-Catalyzed Dehydrogenative Cross-Coupling between Two Azoles

The copper­(II)-catalyzed dehydrogenative coupling between two different azoles for the preparation of unsymmetrical biazoles has been developed. The current catalytic system can effectively control the chemoselectivity for heterocoupling over homocoupling