The possible members of the 51S05^1S_0 meson nonet

The strong decays of the $5^1S_0$ $q\bar{q}$ states are evaluated in the $^3P_0$ model with two types of space wave functions. Comparing the model expectations with the experimental data for the $\pi(2360)$, $\eta(2320)$, $X(2370)$, and $X(2500)$, we suggest that the $\pi(2360)$, $\eta(2320)$, and $X(2500)$ can be assigned as the members of the $5^1S_0$ meson nonet, while the $5^1S_0$ assignment for the $X(2370)$ is not favored by its width. The $5^1S_0$ kaon is predicted to have a mass of about 2418 MeV and a width of about 163 MeV or 225 MeV.Comment: 10 pages, 5 figures, version accepted by Eur. Phys. J.

Micromechanics Fatigue Damage Analysis Modeling for Fabric Reinforced Ceramic Matrix Composites

A micromechanics analysis modeling method was developed to analyze the damage progression and fatigue failure of fabric reinforced composite structures, especially for the brittle ceramic matrix material composites. A repeating unit cell concept of fabric reinforced composites was used to represent the global composite structure. The thermal and mechanical properties of the repeating unit cell were considered as the same as those of the global composite structure. The three-phase micromechanics, the shear-lag, and the continuum fracture mechanics models were integrated with a statistical model in the repeating unit cell to predict the progressive damages and fatigue life of the composite structures. The global structure failure was defined as the loss of loading capability of the repeating unit cell, which depends on the stiffness reduction due to material slice failures and nonlinear material properties in the repeating unit cell. The present methodology is demonstrated with the analysis results evaluated through the experimental test performed with carbon fiber reinforced silicon carbide matrix plain weave composite specimens

The Collins asymmetry in electroproduction of Kaon at the electron ion colliders within TMD factorization

We apply the transverse momentum dependent factorization formalism to investigate the transverse single spin dependent Collins asymmetry with a $\sin(\phi_h+\phi_s)$ modulation in the semi-inclusive production of Kaon meson in deep inelastic scattering process. The asymmetry is contributed by the convolutions of the transversity distribution function $h_1(x)$ of the target proton and the Collins function of the Kaon in the final state. We adopt the available parametrization of $h_1(x)$ as well as the recent extracted result for the Kaon Collins function. To perform the transverse momentum dependent evolution, the parametrization of the nonperturbative Sudakov form factor of the proton and final state Kaon are utilized. We numerically predict the Collins asymmetry for charged Kaon production at the electron ion colliders within the accuracy of next-to-leading-logarithmic order. It is found that the asymmetry is sizable and could be measured. We emphasize the importance of planned electron ion colliders in the aspect of constraining sea quark distribution functions as well as accessing the information of the nucleon spin structure and the hadronization mechanism

Butane-1,2,3,4-tetra­carboxylic acid–4,4′-bipyridine (1/2)

The hydro­thermal reaction of butane-1,2,3,4-tetra­carboxylic acid (H4butca), 4,4′-bipyridine (bipy) and Mn(SO4)2·H2O afforded a new co-crystal, C8H10O8·2C10H8N2 or H4butca·2(bipy), in which strong O—H⋯N hydrogen-bonding and weak π–π stacking [centroid–centroid distance = 3.8459 (19) Å] inter­actions assemble the organic mol­ecules into a three-dimensional supra­molecular framework. C—H⋯O inter­actions are also present. The whole mol­ecule has inversion symmetry

Comparative mitogenomics of Braconidae (Insecta: Hymenoptera) and the phylogenetic utility of mitochondrial genomes with special reference to Holometabolous insects

<p>Abstract</p> <p>Background</p> <p>Animal mitochondrial genomes are potential models for molecular evolution and markers for phylogenetic and population studies. Previous research has shown interesting features in hymenopteran mitochondrial genomes. Here, we conducted a comparative study of mitochondrial genomes of the family Braconidae, one of the largest families of Hymenoptera, and assessed the utility of mitochondrial genomic data for phylogenetic inference at three different hierarchical levels, i.e., Braconidae, Hymenoptera, and Holometabola.</p> <p>Results</p> <p>Seven mitochondrial genomes from seven subfamilies of Braconidae were sequenced. Three of the four sequenced A+T-rich regions are shown to be inverted. Furthermore, all species showed reversal of strand asymmetry, suggesting that inversion of the A+T-rich region might be a synapomorphy of the Braconidae. Gene rearrangement events occurred in all braconid species, but gene rearrangement rates were not taxonomically correlated. Most rearranged genes were tRNAs, except those of <it>Cotesia vestalis</it>, in which 13 protein-coding genes and 14 tRNA genes changed positions or/and directions through three kinds of gene rearrangement events. Remote inversion is posited to be the result of two independent recombination events. Evolutionary rates were lower in species of the cyclostome group than those of noncyclostomes. Phylogenetic analyses based on complete mitochondrial genomes and secondary structure of <it>rrnS </it>supported a sister-group relationship between Aphidiinae and cyclostomes. Many well accepted relationships within Hymenoptera, such as paraphyly of Symphyta and Evaniomorpha, a sister-group relationship between Orussoidea and Apocrita, and monophyly of Proctotrupomorpha, Ichneumonoidea and Aculeata were robustly confirmed. New hypotheses, such as a sister-group relationship between Evanioidea and Aculeata, were generated. Among holometabolous insects, Hymenoptera was shown to be the sister to all other orders. Mecoptera was recovered as the sister-group of Diptera. Neuropterida (Neuroptera + Megaloptera), and a sister-group relationship with (Diptera + Mecoptera) were supported across all analyses.</p> <p>Conclusions</p> <p>Our comparative studies indicate that mitochondrial genomes are a useful phylogenetic tool at the ordinal level within Holometabola, at the superfamily within Hymenoptera and at the subfamily level within Braconidae. Variation at all of these hierarchical levels suggests that the utility of mitochondrial genomes is likely to be a valuable tool for systematics in other groups of arthropods.</p

EGR1, EGFR and IGF1R protein expressions in non-small cell lung cancer and their clinical significances

The purpose of this study was to investigate the incidence and clinical significance of alterations in EGFR, IGF1R and the cell signaling pathway activities induced by them, as well as EGR1 expression in resected non-small cell lung cancer (NSCLC). The protein expressions of  biomarker were evaluated by Western blotting in tissues from 19 surgically resected NSCLCs. High expressions of EGR1, EGFR and  IGF1R were detected in more than 30% tumor tissues. High expressions of pErk and pAkt were detected in more than 50% paracancer tissues. There were significant correlations between the NSCLC target factors detected (p<0.05). Alterations of protein expressions of target factor detected in NSCLC were significantly associated with alterations in pathological subtype, differentiation, pathological stage, and smoking history. Positive EGR1 might be  associated with good survival, while positive pErk might be associated with poor prognosis.

Multiple Lines of Evidence from Mitochondrial Genomes Resolve Phylogenetic Relationships of Parasitic Wasps in Braconidae

The rapid increase in the number of mitochondrial genomes in public databases provides opportunities for insect phylogenetic studies; but it also provides challenges because of gene rearrangements and variable substitution rates among both lineages and sites. Typically, phylogenetic studies use mitochondrial sequence data but exclude other features of the mitochondrial genome from analyses. Here, we undertook large-scale sequencing of mitochondrial genomes from a worldwide collection of specimens belonging to Braconidae, one of the largest families of Metazoa. The strand-asymmetry of base composition in the mitochondrial genomes of braconids is reversed, providing evidence for monophyly of the Braconidae. We have reconstructed a backbone phylogeny of the major lineages of Braconidae from gene order of the mitochondrial genomes. Standard phylogenetic analyses of DNA sequences provided strong support for both Cyclostomes and Noncyclostomes. Four subfamily complexes, that is, helconoid, euphoroid, sigalphoid, and microgastroid, within the Noncyclostomes were reconstructed robustly, the first three of which formed a monophyletic group sister to the last one. Aphidiinae was recovered as a lineage sister to other groups of Cyclostomes, while the Ichneutinae was recovered as paraphyletic. Separate analyses of the subdivided groups showed congruent relationships, employing different matrices and methods, for the internal nodes of the Cyclostomes and the microgastroid complex of subfamilies. This research, using multiple lines of evidence from mitochondrial genomes, illustrates multiple uses of mitochondrial genomes for phylogenetic inference in Braconidae