5,622 research outputs found
Mobility: a double-edged sword for HSPA networks
This paper presents an empirical study on the performance of mobile High Speed Packet Access (HSPA, a 3.5G cellular standard) networks in Hong Kong via extensive field tests. Our study, from the viewpoint of end users, covers virtually all possible mobile scenarios in urban areas, including subways, trains, off-shore ferries and city buses. We have confirmed that mobility has largely negative impacts on the performance of HSPA networks, as fast-changing wireless environment causes serious service deterioration or even interruption. Meanwhile our field experiment results have shown unexpected new findings and thereby exposed new features of the mobile HSPA networks, which contradict commonly held views. We surprisingly find out that mobility can improve fairness of bandwidth sharing among users and traffic flows. Also the triggering and final results of handoffs in mobile HSPA networks are unpredictable and often inappropriate, thus calling for fast reacting fallover mechanisms. We have conducted in-depth research to furnish detailed analysis and explanations to what we have observed. We conclude that mobility is a double-edged sword for HSPA networks. To the best of our knowledge, this is the first public report on a large scale empirical study on the performance of commercial mobile HSPA networks
On the proof of some theorem on locally nilpotent subgroups in division rings
In Hai-Thin (2009), there is a theorem, stating that every locally nilpotent
subnormal subgroup in a division ring is central (see Hai-Thin (2009, Th.
2.2)). Unfortunately, there is some mistake in the proof of this theorem. In
this note we give the another proof of this theorem.Comment: 3 page
Local anaesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro
Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms. This study was to investigate the effects of bupivacaine on ovarian and prostate cancer cell biology and the underlying molecular mechanisms. Cell viability, proliferation and migration of ovarian carcinoma (SKOV-3) and prostate carcinoma (PC-3) were examined following treatment with bupivacaine. Cleaved caspase 3, 8 and 9, and GSK-3β, pGSK-3β(tyr216) and pGSK-3β(ser9) expression were assessed by immunofluorescence. FAS ligand neutralization, caspase and GSK-3 inhibitors and GSK-3β siRNA were applied to further explore underlying mechanisms. Clinically relevant concentrations of bupivacaine reduced cell viability and inhibited cellular proliferation and migration in both cell lines. Caspase 8 and 9 inhibition generated partial cell death reversal in SKOV-3, whilst only caspase 9 was effective in PC-3. Bupivacaine increased the phosphorylation of GSK-3β(Tyr216) in SKOV-3 but without measurable effect in PC3. GSK-3β inhibition and siRNA gene knockdown decreased bupivacaine induced cell death in SKOV-3 but not in PC3. Our data suggests that bupivacaine has direct ‘anti-cancer’ properties through the activation of intrinsic and extrinsic apoptotic pathways in ovarian cancer but only the intrinsic pathway in prostate cancer
Do objects in working memory compete with objects in perception?
It is generally assumed that "perceptual object" is the basic unit for processing visual information and that only a small number of objects can be either perceptually selected or encoded in working memory (WM) at one time. This raises the question whether the same resource is used when objects are selected and tracked as when they are held in WM. In two experiments, we measured dual-task interference between a memory task and a Multiple Object Tracking task. The WM tasks involve explicit, implicit, or no spatial processing. Our results suggest there is no resource competition between working memory and perceptual selection except when the WM task requires encoding spatial properties
Analyst Coverage And The Diversification Discount
We use financial analyst coverage as a measure of information asymmetry to examine excess firm values associated with single- and multi-segment firms. We explicitly examine whether differences in analyst coverage can explain the diversification discount. We find that information asymmetry plays a major role in the valuation of companies and explains a large portion of the diversification discount. However, a significant diversification discount remains after controlling for the effects of analyst coverage
Managerial Incentives And Changes In Corporate Focus
We examine how Chief Executive Officer (CEO) equity ownership, CEO tenure, and the percentage of options in CEO annual compensation are related to decisions regarding changes in corporate focus. We document that the CEOs whose companies change their level of corporate focus have significant differences from CEOs whose firms do not change focus. However, we find no differences in the characteristics of CEOs who increase their firm’s level of diversification and the CEOs who decrease their firm’s level of diversification. Firm characteristics, such as size or whether the firm sells at a premium or discount to its peers, are better predictors of changes in corporate focus than CEO characteristics. Overall, we find no evidence that changes in diversification are related to self-serving managers attempting to maximize their own wealth
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