49,169 research outputs found
Automatic Extraction of Commonsense LocatedNear Knowledge
LocatedNear relation is a kind of commonsense knowledge describing two
physical objects that are typically found near each other in real life. In this
paper, we study how to automatically extract such relationship through a
sentence-level relation classifier and aggregating the scores of entity pairs
from a large corpus. Also, we release two benchmark datasets for evaluation and
future research.Comment: Accepted by ACL 2018. A preliminary version is presented on
AKBC@NIPS'1
Valley-dependent Brewster angles and Goos-Hanchen effect in strained graphene
We demonstrate theoretically how local strains in graphene can be tailored to
generate a valley polarized current. By suitable engineering of local strain
profiles, we find that electrons in opposite valleys (K or K') show different
Brewster-like angles and Goos-H\"anchen shifts, exhibiting a close analogy with
light propagating behavior. In a strain-induced waveguide, electrons in K and
K' valleys have different group velocities, which can be used to construct a
valley filter in graphene without the need for any external fields.Comment: 5 pages, 4 figure
SDF1 Gene Variation Is Associated with Circulating SDF1 alpha Level and Endothelial Progenitor Cell Number-The Bruneck Study
BACKGROUND: Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation. It would be interesting to assess the predictive value of SDF-1alpha level for EPC number, and to ascertain whether there is a relationship between SDF1 gene variation, plasma SDF-1alpha level, and the number and function of circulating EPCs. We also tested whether EPC number and function was related to CXCR4 gene variation.
METHODOLOGY AND PRINCIPAL FINDINGS: We genotyped a cohort of individuals who participated in the Bruneck Study for single nucleotide polymorphisms (SNPs) in the SDF1 and CXCR4 genes, and measured blood SDF1alpha level as well as EPC number and function. SDF1alpha levels were correlated with age, gender, alcohol consumption, circulating reticulocyte numbers, and concentrations of matrix metalloproteinase-9, C-reactive protein, cystatin C, fibrinogen and homocytein. In blood samples taken in 2005, EPC number was inversely associated with SDF1alpha level (p<0.001). EPC number in 2005 was also inversely associated with SDF1alpha level in 2000 (p = 0.009), suggesting a predictive value of plasma SDF1alpha level for EPC number. There was an association between the SDF1 gene rs2297630 SNP A/A genotype, increased SDF1alpha level (p = 0.002) and lower EPC number (p = 0.006).
CONCLUSIONS: Our data indicate that a SDF1 gene variation (rs2297630) has an influence on SDF1alpha level and circulating EPC number, and that plasma SDF1alpha level is a predictor of EPC number
Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study
BACKGROUND AND PURPOSE: Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis. In the current evaluation, we tested the hypothesis that sHSP60 levels are associated with the progression of carotid arteriosclerosis, prospectively. METHODS: The association of sHSP60 with early atherogenesis (5-year development and progression of nonstenotic carotid plaques) was investigated as part of the population-based prospective Bruneck Study. The current study focused on the follow-up period between 1995 and 2000 and, thus, included 684 subjects. RESULTS: sHSP60 levels measured in 1995 and 2000 were highly correlated (r=0.40; P<0.001), indicating consistency over a 5-year period. Circulating HSP60 levels were significantly correlated with antilipopolysaccharide and anti-HSP60 antibodies. It was also elevated in subjects with chronic infection (top quintile group of HSP60, among subjects with and without chronic infection: 23.8% versus 17.0%; P=0.003 after adjustment for age and sex). HSP60 levels were significantly associated with early atherogenesis, both in the entire population (multivariate odds ratio, for a comparison between quintile group V versus I+II: 2.0 [1.2 to 3.5] and the subgroup free of atherosclerosis at the 1995 baseline: 3.8 [1.6 to 8.9]). The risk of early atherogenesis was additionally amplified when high-sHSP60 and chronic infection were present together. CONCLUSIONS: Our study provides the first prospective data confirming an association between high levels of sHSP60 and early carotid atherosclerosis. This possibly indicates an involvement of sHSP60 in activating proinflammatory processes associated with early vessel pathology
Scaling property of ideal granitic sequences
Quantification of granite textures and structures using a mathematical model for characterization of granites has been a long-term attempt of mathematical geologists over the past four decades. It is usually difficult to determine the influence of magma properties on mineral crystallization forming fined-grained granites due to its irregular and fine-grained textures. The ideal granite model was originally developed for modeling mineral sequences from first and second-order Markov properties. This paper proposes a new model for quantifying scale invariance properties of mineral clusters and voids observed within mineral sequences. Sequences of the minerals plagioclase, quartz and orthoclase observed under the microscope for 104 aplite samples collected from the Meech Lake area, Gatineau Park, QuΓ©bec were used for validation of the model. The results show that the multi-scale approaches proposed in this paper may enable quantification of the nature of the randomness of mineral grain distributions. This, in turn, may be related to original properties of the magma
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