Three-dimensional numerical study of flow characteristic and membrane fouling evolution in an enzymatic membrane reactor

In order to enhance the understanding of membrane fouling mechanism, the hydrodynamics of granular flow in a stirred enzymatic membrane reactor was numerically investigated in the present study. A three-dimensional Euler-Euler model, coupled with k-e mixture turbulence model and drag function for interphase momentum exchange, was applied to simulate the two-phase (fluid-solid) turbulent flow. Numerical simulations of single- or two-phase turbulent flow under various stirring speed were implemented. The numerical results coincide very well with some published experimental data. Results for the distributions of velocity, shear stress and turbulent kinetic energy were provided. Our results show that the increase of stirring speed could not only enlarge the circulation loops in the reactor, but it can also increase the shear stress on the membrane surface and accelerate the mixing process of granular materials. The time evolution of volumetric function of granular materials on the membrane surface has qualitatively explained the evolution of membrane fouling.Comment: 10 panges, 8 figure

On Shapley Value in Data Assemblage Under Independent Utility

In many applications, an organization may want to acquire data from many data owners. Data marketplaces allow data owners to produce data assemblage needed by data buyers through coalition. To encourage coalitions to produce data, it is critical to allocate revenue to data owners in a fair manner according to their contributions. Although in literature Shapley fairness and alternatives have been well explored to facilitate revenue allocation in data assemblage, computing exact Shapley value for many data owners and large assembled data sets through coalition remains challenging due to the combinatoric nature of Shapley value. In this paper, we explore the decomposability of utility in data assemblage by formulating the independent utility assumption. We argue that independent utility enjoys many applications. Moreover, we identify interesting properties of independent utility and develop fast computation techniques for exact Shapley value under independent utility. Our experimental results on a series of benchmark data sets show that our new approach not only guarantees the exactness of Shapley value, but also achieves faster computation by orders of magnitudes.Comment: Accepted by VLDB 202

2-Chloro­methyl-2,3-dihydro­thieno[3,4-b][1,4]dioxine

In the mol­ecule of the title compound, C7H7ClO2S, the six-membered ring adopts a twisted conformation. In the crystal structure, weak inter­molecular C—H⋯O hydrogen bonds link the mol­ecules. There is also a weak C—H⋯π inter­action

To aggregate or not to aggregate high-dimensional classifiers

<p>Abstract</p> <p>Background</p> <p>High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually much smaller in the order of ten or hundred. This poses statistical challenges and calls for appropriate solutions for the analysis of this kind of data.</p> <p>Results</p> <p>Principal component discriminant analysis (PCDA), an adaptation of classical linear discriminant analysis (LDA) for high-dimensional data, has been selected as an example of a base learner. The multiple versions of PCDA models from repeated double cross-validation were aggregated, and the final classification was performed by majority voting. The performance of this approach was evaluated by simulation, genomics, proteomics and metabolomics data sets.</p> <p>Conclusions</p> <p>The aggregating PCDA learner can improve the prediction performance, provide more stable result, and help to know the variability of the models. The disadvantage and limitations of aggregating were also discussed.</p