774 research outputs found
Measuring Rural Poverty in China: a Case Study Approach
This paper measures rural poverty in Hubei Province and Inner Mongolia in China. The poverty lines we derived by Ravallion's method differ from the official Chinese poverty lines. The official pan-country poverty line underestimates rural poverty in Hubei Province and overestimates rural poverty in Inner Mongolia. Poverty determinants are estimated by Logit as well as Probit models. The study notes that factors such as living in a mountainous area, lack of better irrigation conditions, a large family size, few fixed assets, few land owned and sole dependence on agriculture as a livelihood source would make a rural household more vulnerable to poverty. On the other hand, a rural household whose members are either better educated or trained laborers would statistically be less poor. The growth-redistribution decomposition reveals that for all the three FGT indexes in Hubei province, income growth contributed much to the alleviation of poverty, while the redistribution or inequality effects counteracted the growth effects and worsened poverty. The poverty incidence decomposition results reveal that about one third of the growth effects had been counteracted by the redistribution effects. This implies that future anti-poverty programs should pay more attention to solving the inequality problem in China. Poverty dominance analysis also helps us better understand the poverty situation. It reveals that rural poverty in Inner Mongolia is more severe than that in Hubei, and that poverty incidence in Hubei has lessened from 1997 to 2003, which are the same findings as those drawn from deriving poverty lines.Rural Poverty Line, Poverty Determinants, Growth Redistribution Decomposition, Poverty Dominance, China
Energy Consumption per GDP in Various Regions of China and Its Mode
AbstractBased on the analysis of the changes of Energy consumption per GDP in various regions of China, we can summarize modes of Energy consumption per GDP in various regions of China. The modes are Conventional mode, Gradational mode Contemporary mode, Low-carbon mode. Then, analyse the energy consumption characteristics of each mode and give optimizational initiatives
Climate change and its influence on the Karst groundwater recharge in the Jinci Spring Region, Northern China
Due to climate change and human activities over the last fifty years, the spring flow
volume of karst groundwater has sharply diminished in China. Climate change is one of the critical
factors that initiates a series of karst hydrogeologic and water ecological environmental problems,
because the precipitation shows a decreasing trend while the temperature shows an increasing trend.
The Jinci Spring is one of the largest, most famous springs in northern China. This study employed
data from the Taiyuan Meteorological Station and ten precipitation stations in and around the Jinci
Spring region as well as the runoff data gathered from two hydrological monitoring stations during
1960-2012. The sliding average method and the Mann-Kendall test were used to analyze the variation
tendency of precipitation, temperature, and land evaporation in this area. Finally, the following
were calculated: the varying pattern of the karst groundwater recharge amount and the response
of the recharge amount to precipitation, land evaporation, and river runoff by quantitative analysis.
The results indicated that the precipitation and land evaporation amount decreased at first and then
subsequently increased. Likewise, the variation trend of the karst groundwater recharge amount
in the spring region was roughly consistent with the precipitation variation pattern. In contrast,
the temperature displayed an increasing trend. The climate change resulted in a reduction of the
karst groundwater recharge amount, and it had the greatest influence in the 1990s, which caused the
karst groundwater recharge amount to decrease 26.75 mm as compared to that of the 1960s (about
39.68% lower than that of the 1960s). The Jinci Spring had zero flow during this period. The reduction
in precipitation was one of main factors that caused the cutoff of the Jinci Spring.IS
An experimental study on monitoring of marine sediment transport by using a 3D sediment trap
The observation and analysis of sediment transport in oceans is an important means for the protection of the marine environment, resource development, construction engineering, and element cycling. However, traditional methods of observing sediment transport are either limited by the range of the instruments used or their own observational attributes, such that they cannot be used to accurately detect and analyze the process of transport of marine sediment. A 3D sediment trap has been proposed to compensate for the shortcomings of the various monitoring tools in our team, but no mature method for the analytical inversion of the data obtained from this device has been developed to date. In this paper, we developed analytical methods to invert sediment transport processes using corrected capture efficiency, sample inversion, and transport flux analysis. Through an annular flume test, we measured the turbidity, pressure, and particle size of the water stream and substituted them into the proposed analytical equations, thus verifying the applicability of the analytical methods. We used the slice experiment of the time series of the sediment samples, to determine the validity of the sample inversion, and establish the relationship between the particle size and concentration of the captured samples. We performed restoration tests on the process of sediment transport to establish a set of methods of flux analysis based on the velocity and turbidity of flow. And finally corrected for capture efficiency by particle size. The combination of analytical methods and 3D sediment trap could provide technological support for investigating the evolution of the sea, ecological cycle, and marine engineering
Aboveground dry matter and grain yield of summer maize under different varieties and densities in North China Plain
To increase summer maize grain yield in North China Plain, we conducted field experiments with three densities (3, 6, and 9 plants m-2) on two plant types (a flat type, LD981, and a compact type, LD818) during 2010 and 2011 summer maize growing seasons to study leaf area index (LAI), above ground dry matter accumulation, grain filling rate, and grain yield. The results indicated that with the density increased, the LAI in the both varieties enhanced; however, plant density at the rate of 9 plants m-2 significantly (LSD, P < 0.05) increased LAI in LD818. Increasing densities enhanced the above ground dry matter of LD818, but not of LD981. With the density increased, the grain filling rate in the both varieties declined, but during the later growing season, the grain filling rate in LD818 was higher than that in LD919. Irrespective of plant density at the rate of from 3 to 6 or 6 to 9 plants m-2, the grain No. per ear, 1,000-kernel weight, and ears No. per m2 in LD981 were all lower than those in LD818; this was the main reason why with the increased density, the population yield in LD981 was lower than that in LD818. These results indicate that in North China Plain, increasing plant density could enhance the grain yield of compact type summer maize
Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis
BACKGROUND: A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis. However, the RNA-editing activities in early human embryonic development have not been investigated. RESULTS: Here, we characterized genome-wide A-to-I RNA-editing activities during human early embryogenesis by profiling 68 single cells from 29 human embryos spanning from oocyte to morula stages. We demonstrate dynamic changes in genome-wide RNA-editing during early human embryogenesis in a stage-specific fashion. In parallel with ADAR expression level changes, the genome-wide A-to-I RNA-editing levels in cells remained relatively stable until 4-cell stage, but dramatically decreased at 8-cell stage, continually decreased at morula stage. We detected 37 non-synonymously RNA-edited genes, of which 5 were frequently found in cells of multiple embryonic stages. Moreover, we found that A-to-I editings in miRNA-targeted regions of a substantial number of genes preferably occurred in one or two sequential stages. CONCLUSIONS: Our single-cell analysis reveals dynamic changes in genome-wide RNA-editing during early human embryogenesis in a stage-specific fashion, and provides important insights into early human embryogenesis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-016-3115-2) contains supplementary material, which is available to authorized users
Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis
<p>Abstract</p> <p>Background</p> <p>Dll4/Notch and Ephrin-B2/EphB4 pathways play critical roles in tumor vessel development and maturation. This study evaluates the efficacy of the inhibition of both signaling pathways, alone and in combination, in reducing the growth of an autochthonous mouse tumor and assesses potential adverse effects.</p> <p>Methods</p> <p>We used the transgenic RIP1-Tag2 tumor model to study the effects of 1) inhibition of Dll4/Notch by either <it>Dll4 </it>allelic deletion or use of a soluble extracellular Dll4 (sDll4), 2) inhibition of Ephrin-B2/EphB4 signaling by a soluble extracellular EphB4 fused to albumin (sEphB4-Alb), and 3) inhibition of both pathways by sEphB4-Alb combined with either <it>Dll4 </it>allelic deletion or sDll4. To investigate adverse effects, we used inducible endothelial-specific <it>Dll4 </it>knock-out mice, treated with sEphB4-Alb, and carried out histopathological analysis.</p> <p>Results</p> <p><it>Dll4 </it>allele deletion or soluble Dll4 treatment resulted in increased tumor vessel density, reduced mural cell recruitment and vessel perfusion which resulted in reduced tumor size. The soluble EphB4 instead reduced vessel density and vessel perfusion, leading to reduction of tumor size. Greater efficacy was observed when sEphB4-Alb was combined with either <it>Dll4 </it>allele deletion or sDll4 in regards to tumor size, vessel perfusion and mural cell recruitment. Induced endothelial specific <it>Dll4 </it>loss-of-function caused hepatic vascular alterations, which were prevented by concomitant sEphB4-Alb treatment.</p> <p>Conclusion</p> <p>Combination targeting of Dll4/Notch and Ephrin-B2/EphB4 has potential for clinical investigation, providing cumulative efficacy and increased safety over Dll4/Notch inhibition alone.</p
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