Image Super-Resolution Based on Sparse Coding with Multi-Class Dictionaries

Sparse coding-based single image super-resolution has attracted much interest. In this paper, a super-resolution reconstruction algorithm based on sparse coding with multi-class dictionaries is put forward. We propose a novel method for image patch classification, using the phase congruency information. A sub-dictionary is learned from patches in each category. For a given image patch, the sub-dictionary that belongs to the same category is selected adaptively. Since the given patch has similar pattern with the selected sub-dictionary, it can be better represented. Finally, iterative back-projection is used to enforce global reconstruction constraint. Experiments demonstrate that our approach can produce comparable or even better super-resolution reconstruction results with some existing algorithms, in both subjective visual quality and numerical measures

A non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscle

The myogenic differentiation 1 (MyoD) gene is a master regulator of myogenesis. We previously reported that the expression of MyoD mRNA oscillates over 24 h in skeletal muscle and that the circadian clock transcription factors, BMAL1 (brain and muscle ARNT-like 1) and CLOCK (circadian locomotor output cycles kaput), were bound to the core enhancer (CE) of the MyoD gene in vivo. In this study, we provide in vivo and in vitro evidence that the CE is necessary for circadian expression of MyoD in adult muscle. Gel shift assays identified a conserved non-canonical E-box within the CE that is bound by CLOCK and BMAL1. Functional analysis revealed that this E-box was required for full activation by BMAL1/CLOCK and for in vitro circadian oscillation. Expression profiling of muscle of CEloxP/loxP mice found approximately 1300 genes mis-expressed relative to wild-type. Based on the informatics results, we analyzed the respiratory function of mitochondria isolated from wild-type and CEloxP/loxP mice. These assays determined that State 5 respiration was significantly reduced in CEloxP/loxP muscle. The results of this work identify a novel element in the MyoD enhancer that confers circadian regulation to MyoD in skeletal muscle and suggest that loss of circadian regulation leads to changes in myogenic expression and downstream mitochondrial function

Existence of positive solutions for singular fractional differential equations with integral boundary conditions

This article shows the existence of a positive solution for the singular fractional differential equation with integral boundary condition $$displaylines{ {}^C!D^p u(t)=lambda h(t)f(t, u(t)), quad tin(0, 1), cr u(0)-au(1)=int^1_0g_0(s)u(s),ds, cr u'(0)-b,{}^C!D^qu(1)=int^1_0g_1(s)u(s),ds, cr u''(0)=u'''(0)=dots =u^{(n-1)}(0)=0, }$$ where $lambda$ is a parameter and the nonlinear term is allowed to be singular at $t=0, 1$ and $u=0$. We obtain an explicit interval for $lambda$ such that for any $lambda$ in this interval, existence of at least one positive solution is guaranteed. Our approach is by a fixed point theory in cones combined with linear operator theory

Retracted Article: Research on Laser Dazzle Simulation Using ZEMAX Software and MATLAB

This article published in MATEC Web of Conferences has been formally retracted on ethical grounds because the article contains extensive and repeated instances of plagiarism

Retracted Article: Research on Laser Dazzle Simulation Using ZEMAX Software and MATLAB

This article published in MATEC Web of Conferences has been formally retracted on ethical grounds because the article contains extensive and repeated instances of plagiarism

RASSF10 is Epigenetically Inactivated and Suppresses Cell Proliferation and Induces Cell Apoptosis by Activating the p53 Signalling Pathway in Papillary Thyroid Carcinoma Cancer

Objectives: We aimed to confirm whether RASSF10 activated the p53 signalling pathway, thereby modulating cell proliferation, migration, invasion, and apoptosis in papillary thyroid carcinoma (PTC) cells. Methods: A total of 108 PTC tissue samples and normal adjacent tissues were obtained. RT-PCR and Western blotting analyses were performed to detect RASSF10 expression, and methylation levels of RASSF10 were estimated by methylation-specific PCR (MSP). We also detected the expression and methylation status of RASSF10 in both a human PTC cell line (K1) and a normal thyroid cell line (FRTL5). After transfection of cells with empty vector pcDNA3.1, pcDNA3.1-RASSF10, p53 siRNA and shRASSF10, Coulter counter, colony-formation, wound healing, Transwell and flow cytometry analyses were performed to examine the role of RASSF10 in cell proliferation, migration, invasion, and apoptosis. Finally, the expression of p53, p21, Bcl-2 and Bax were detected using Western Blotting analyses. Results: RASSF10 expression in PTC tissues was significantly lower and hyper-methylated compared to normal adjacent tissues. In addition, RASSF10 was significantly down-regulated and hyper-methylated in K1 cells compared to FRTL5 cells. In addition, suppressed proliferation and significantly induced apoptosis of K1 cells were observed after transfection with pcDNA3.1-RASSF10 (P < 0.05). Furthermore, RASSF10 activated the p53 signalling pathway and regulated the expression of p53, p21, Bcl-2 and Bax. Furthermore, p53 siRNA could antagonize the effects of RASSF10 in K1 cells. Conclusions: RASSF10 induces apoptosis in PTC cells by activating the p53 signalling pathway, indicating its role as a treatment target for PTC

Josephson radiation patterns in underdamped topological Josephson junctions

Josephson radiation is a useful signature for detecting Majorana zero modes in topological superconductors. We study the Josephson radiation of the underdamped topological Josephson junction within the quantum resistively and capacitively shunted junction model. We show that the quantum dynamics of the Majorana two-level system induce oscillatory patterns in the Josephson emission spectra. With the Floquet method, we obtain analytical results for these oscillatory patterns and find that they are well described by Bessel functions. We perform numerical simulations to verify the analytical results and demonstrate that these Bessel radiation patterns exist for a wide range of junction parameters.Comment: Accepted for publication as a Regular Article in Physical Review

Improvement of RNA In Situ Hybridisation for Grapevine Fruits and Ovules

The European grapevine (Vitis vinifera L.) is one of the world’s most widely cultivated and economically important fruit crops. Seedless fruits are particularly desired for table grapes, with seedlessness resulting from stenospermocarpy being an important goal for cultivar improvement. The establishment of an RNA in situ hybridisation (ISH) system for grape berries and ovules is, therefore, important for understanding the molecular mechanisms of ovule abortion in stenospermocarpic seedless cultivars. We improved RNA in situ hybridisation procedures for developing berries and ovules by targeting two transcription factor genes, VvHB63 and VvTAU, using two seeded varieties, ‘Red Globe’ and ‘Pinot Noir’, and two seedless cultivars, ‘Flame Seedless’ and ‘Thompson Seedless’. Optimisation focused on the time of proteinase K treatment, probe length, probe concentration, hybridisation temperature and post-hybridisation washing conditions. The objectives were to maximise hybridisation signals and minimise background interference, while still preserving tissue integrity. For the target genes and samples tested, the best results were obtained with a pre-hybridisation proteinase K treatment of 30 min, probe length of 150 bp and concentration of 100 ng/mL, hybridisation temperature of 50 °C, three washes with 0.2× saline sodium citrate (SSC) solution and blocking with 1% blocking reagent for 45 min during the subsequent hybridisation. The improved ISH system was used to study the spatiotemporal expression patterns of genes related to ovule development at a microscopic level