Relation between vitamin D concentrations and (a) HOMA-IR, and (b) TC/HDL ratio.

<p>Relation between vitamin D concentrations and (a) HOMA-IR, and (b) TC/HDL ratio.</p

Additional file 1: of Correlation of adiposity indices with cardiovascular disease risk factors in healthy adults of Singapore: a cross-sectional study

Supporting information. Table S1. Correlation coefficients of anthropometric measurements and PBF with cardiovascular risk factors for all participants. Figure S1. Correlation coefficients between different anthropometric measurements and CVD risk factors in female participants. Figure S2. Correlation coefficients between different anthropometric measurements and CVD risk factors in male participants. (DOCX 25 kb

Gene Detection in Complex Biological Media Using Semiconductor Nanorods within an Integrated Microfluidic Device

The salient optical properties of highly luminescent semiconductor nanocrystals render them ideal fluorophores for clinical diagnostics, therapeutics, and highly sensitive biochip applications. Microfluidic systems allow miniaturization and integration of multiple biochemical processes in a single device and do not require sophisticated diagnostic tools. Herein, we describe a microfluidic system that integrates RNA extraction, reverse transcription to cDNA, amplification and detection within one integrated device to detect histidine decarboxylase (HDC) gene directly from human white blood cells samples. When anisotropic semiconductor nanorods (NRs) were used as the fluorescent probes, the detection limit was found to be 0.4 ng of total RNA, which was much lower than that obtained using spherical quantum dots (QDs) or organic dyes. This was attributed to the large action cross-section of NRs and their high probability of target capture in a pull-down detection scheme. The combination of large scale integrated microfluidics with highly fluorescent semiconductor NRs may find widespread utility in point-of-care devices and multitarget diagnostics