The Role of Personal Therapy for Chinese-Speaking Music Therapy Students: A Survey

The purpose of this study is to understand the perceptions of Chinese-speaking music therapy students on cultural transition and personal therapy and to determine what impact these have on their learning process. An online questionnaire surveyed 13 Chinese-speaking music therapy students. Nine completed responses were analyzed by using both quantitative and qualitative methods. The questions focused on their demographic information, their attitudes toward personal therapy, and their attitudes toward the cultural transition process. The study found that 78% of participants sought any type of therapy and 55% of participants believe that personal therapy is extremely important for music therapy students. No one stated feeling stigmatized for receiving personal therapy. In addition, 89% of participants reported they had talked about their cultural transition process with others and believe personal therapy can help them adjust culturally in the United States. This study may provide valuable insights for school instructors, clinical supervisors, and personal therapists to improve their understanding and awareness about the struggles of Chinese-speaking music therapy students and the cultural transition process. This may also have positive effects on personal and professional growth for Chinese-speaking music therapy students

Автономная система для низкочастотной импульсной магнитотерапии

Терапевтическое свойства магнитного поля получили широкое распространение в клинической практике. В работе представлена автономная система для низкочастотной импульсной магнитотерапии, отвечающая современным требованиям медицины. Пр ведены схемотехнические особенности устройства. Критериями при разработке аппарата являются: автономность, информативность, простота в управлении. Режим работы устройства задается при помощи микропроцессорной системы управления. Для обмена данными с персональным компьютером используется модуль беспроводной связи. Индуктор выполнен на основе двухобмоточного воздушного дросселя для формирования магнитного потока в двух направлениях. Для удаленного задания режима работы системы с персонального компьютера разработан интерфейс пользователя, позволяющий задать время терапии и интенсивность воздействия магнитным полем на организм. Информация о текущем режиме работы отображается как на мониторе компьютера, так и на сенсорном дисплее аппарата

Quinolinone inhibits proliferation of gastric cancer cells and induces their apoptosis via down-regulation of the expression of pro-oncogene c-Myc

Purpose: To determine the anti-proliferative potential of quinolinone against gastric cancer cells, and the underlying mechanism of action.Methods: Quinolinone-mediated proliferative changes were measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, while its effect on apoptosis was determined by flow cytometry. Transwell and wound healing assays were used for the determination of the effect of quinolinone on cell invasion and migration. The effect of quinolinone on protein expression levels were assayed with western blotting.Results: Quinolinone caused reduction in gastric cancer cell viability, but it had no effect on normal (GES-1) cells. Treatment with 8 μM quinolinone reduced the viability of SNU-5 and SGC-7901 cells to 32 and 27 %, respectively. Moreover, 8 μM quinolinone induced 67.90 and 71.54 % apoptosis in SNU-5 and SGC-7901 cells, respectively. Quinolinone significantly increased the population of cells in G1 phase, and suppressed migration potential (p < 0.05). Furthermore, in quinolinone-treated cells, the expression levels of p-PI3K, c-Myc and p-AKT were much lower than those in untreated cells (p < 0.05). Quinolinone also downregulated the expressions of MMP-2 and MMP-9, while it upregulated p21 expression in SNU-5 and SGC-7901 cells.Conclusion: Quinolinone suppresses the growth of SNU-5 and SGC-7901 gastric cancer cells via cell cycle arrest, induction of apoptosis and downregulation of the expressions of c-Myc and metalloproteinases. Thus, quinolinone may be developed as a potential drug candidate for the treatment of gastric cancer. Keywords: Gastric cancer, Apoptosis, Metalloproteinases, Phosphorylatio

Paradoxical constitutive law between donor O-H bond length and its stretching frequency in water dimer

The constitutive laws of hydrogen bonds (H-bonds) are central to understanding microphysical processes not precisely observed, especially in terms of structural properties. Previous experiences in water H-bonding revealed that as the intermolecular O...O distance shortens, the O-H stretching frequency redshifts; thus, an elongated O-H bond length can be empirically inferred, which is described as the constitutive law under the cooperative effect. Here, using the high-precision CCSD(T) method, we report a violation of the conventional constitutive law in water dimer. That is, when the variation in the O...O distance changes from stretching by 0.06 to contracting by -0.15 angstrom compared to the equilibrium position, the donor O-H bond length decreases from 0.9724 to 0.9717 angstrom, and the O-H stretching frequency redshifts from 3715 to 3708 cm-1. Our work highlights that the O-H bond length decreases simultaneously with its stretching frequency, which is clearly inconsistent with the previously recognized constitutive law.Comment: 10 pages, 2 figure

KNOWLEDGE TRANSFERRING PATH BASED ON KNOWLEDGE LINK——THE KNOWLEDGE TRANSFER OF SCIENTIFIC AND TECHNOLOGICAL ACHIVEMENTS AS AN EXAMPLE

Scientific and technological achievements which are used in the life become more and more prominent, and gradually change the people live way. In order to meet the needs of society, it is important do scientific achievements better, knowledge transfer should be the focus of the current knowledge management. This paper first clarifies the related concepts of knowledge chain, knowledge transfer, key path, and then shows the basic connotation of knowledge transfer of scientific and technological achievements, analyzes how scientific and technological achievements are transformed, and finally establishes the knowledge transfer path model of scientific and technological achievements. This paper validates the superiority of the model to solve the real problem, and provides the theoretical basis for the determination of the scientific and technological achievements into the key path of the real product, and has certain practical significance