Arithmetics of Uncertainty Distributions for Some Functions of Uncertain Variables with Experiential Uncertainty Distributions

Uncertainty distributions for functions of uncertain variables in uncertainty theory play a significant rote. The paper provides the arithmetics of uncertainty distributions for sum, difference, maxi- mum and minimum of uncertain variables with experiential uncertainty distributions, and shows the efficiency of these arithmetics by examples

The Analysis and Calculation Method of Urban Rail Transit Carrying Capacity Based on Express-Slow Mode

Urban railway transport that connects suburbs and city areas is characterized by uneven temporal and spatial distribution in terms of passenger flow and underutilized carrying capacity. This paper aims to develop methodologies to measure the carrying capacity of the urban railway by introducing a concept of the express-slow mode. We first explore factors influencing the carrying capacity under the express-slow mode and the interactive relationships among these factors. Then we establish seven different scenarios to measure the carrying capacity by considering the ratio of the number of the express trains and the slow trains, the station where overtaking takes place, and the number of overtaking maneuvers. Taking Shanghai Metro Line 16 as an empirical study, the proposed methods to measure the carrying capacity under different express-slow mode are proved to be valid. This paper contributes to the literature by remodifying the traditional methods to measure the carrying capacity when different express-slow modes are applied to improve the carrying capacity of the suburban railway

Self-doping effect in confined copper selenide semiconducting quantum dots for efficient photoelectrocatalytic oxygen evolution

Self-doping can not only suppress the photogenerated charge recombination of semiconducting quantum dots by self-introducing trapping states within the bandgap, but also provide high-density catalytic active sites as the consequence of abundant non-saturated bonds associated with the defects. Here, we successfully prepared semiconducting copper selenide (CuSe) confined quantum dots with abundant vacancies and systematically investigated their photoelectrochemical characteristics. Photoluminescence characterizations reveal that the presence of vacancies reduces the emission intensity dramatically, indicating a low recombination rate of photogenerated charge carriers due to the self-introduced trapping states within the bandgap. In addition, the ultra-low charge transfer resistance measured by electrochemical impedance spectroscopy implies the efficient charge transfer of CuSe semiconducting quantum dots-based photoelectrocatalysts, which is guaranteed by the high conductivity of their confined structure as revealed by room-temperature electrical transport measurements. Such high conductivity and low photogenerated charge carriers recombination rate, combined with high-density active sites and confined structure, guaranteeing the remarkable photoelectrocatalytic performance and stability as manifested by photoelectrocatalysis characterizations. This work promotes the development of semiconducting quantum dots-based photoelectrocatalysis and demonstrates CuSe semiconducting quantum confined catalysts as an advanced photoelectrocatalysts for oxygen evolution reaction

Cluster-Like Headache Secondary to Anamnesis of Sphenoid Ridge Meningioma: A Case Report and Literature Review

Cluster headache is generally considered to be a primary headache; secondary cluster-like headache is quite rare, while cluster-like headache secondary to meningioma is even rarer. Here, we describe an unusual case with cluster-like headache 2.5 years after sphenoid ridge meningioma surgery. The cluster-like headache and meningioma were on the same side, and even at the same position. Furthermore, the cluster-like headache lasted for 6 months. In addition, the patient did not respond well to conventional treatments for cluster headache, such as oxygen inhalation, carbamazepine, and tramadol. Brain magnetic resonance imaging demonstrated a softening lesion, glial hyperplasia, and localized thickening and enhancement of the dura in the left frontal-temporal lobe. However, positron-emission computed tomography showed reduced metabolism in the left frontal-temporal lobe. Although the possibility of a primary headache cannot be completely eliminated, the association between cluster-like headache and probable tumor recurrence or postoperative changes should be considered

In vitro and in vivo mRNA delivery using lipid-enveloped pHresponsive polymer nanoparticles

Biodegradable core−shell structured nanoparticles with a poly(β-amino ester) (PBAE) core enveloped by a phospholipid bilayer shell were developed for in vivo mRNA delivery with a view toward delivery of mRNA-based vaccines. The pH-responsive PBAE component was chosen to promote endosome disruption, while the lipid surface layer was selected to minimize toxicity of the polycation core. Messenger RNA was efficiently adsorbed via electrostatic interactions onto the surface of these net positively charged nanoparticles. In vitro, mRNA-loaded particle uptake by dendritic cells led to mRNA delivery into the cytosol with low cytotoxicity, followed by translation of the encoded protein in these difficult-to-transfect cells at a frequency of 30%. Particles loaded with mRNA administered intranasally (i.n.) in mice led to the expression of the reporter protein luciferase in vivo as soon as 6 h after administration, a time point when naked mRNA given i.n. showed no expression. At later time points, luciferase expression was detected in naked mRNA-treated mice, but this group showed a wide variation in levels of transfection, compared to particle-treated mice. This system may thus be promising for noninvasive delivery of mRNA-based vaccines.United States. Dept. of Defense (Institute for Soldier Nanotechnology, contract W911NF-07-D-0004)Ragon Institute of MGH, MIT and HarvardSingapore. Agency for Science, Technology and ResearchHoward Hughes Medical Institute (Investigator

Values of Magnetic Resonance Imaging and Computed Tomography in the Diagnosis of Patients with Syndromes of Subacromial Impingement

Subacromial impingement syndrome (SIS) is defined as pressurization and impingement between the acromion, the bursa under the acromion, and the rotator cuff during the abduction and elevation of the shoulder joint, resulting in pain and a functional disturbance of elevation. It is the most common disorder of the shoulder, accounting for 44-65% of all complaints of shoulder pain during a physician’s office visit. The study was performed with the aim of valuing the magnetic resonance imaging (MRI) and computed tomography (CT) in diagnosing patients with SIS. A total of 68 patients with SIS were selected as study subjects and subjected to MRI and CT examinations. The diagnostic accuracy and sensitivity of MRI and CT were, respectively, 97.06 and 70.59% (P0.05). In conclusion, the diagnostic accuracy, sensitivity, and detection rate of acromion of MRI were higher compared with those of CT examination, and MRI is more suitable in the clinical diagnosis of SIS

Preparation of mesoporous titania film using nonionic triblock copolymer as surfactant template

International audienc

Open Tubular Column Immobilized with Covalent Organic Frameworks for Rapid Separation of Small Molecular Compounds by Capillary Electrochromatography

Preparation of a novel TpBD (synthesized from phloroglucinol and benzidine) covalent organic framework (COF) immobilized open-tubular (OT) capillary is described by in situ growth strategy. The stationary phase in the column was characterized by Fourier transform infrared (FTIR) spectra, X-ray diffraction (XRD), thermogravimetric analysis (TGA), nitrogen adsorption–desorption isotherms, scanning electron microscope (SEM), transmission electron microscopy (TEM) and energy-dispersive X-ray spectrum (EDS). Several families of compounds with different properties (alkylbenzenes, parabens, sulfonamides and benzoic acids) were selected to evaluate the performance of the TpBD COF immobilized capillary. The results showed that the stationary phase was uniform with about 6.0 μm thickness under the optimal preparation conditions, and the relative standard deviations (RSDs) were no more than 3.13% of alkylbenzenes on the TpBD COF immobilized capillary for 11 consecutive runs, which exhibited its excellent reproducibility and stability. A rapid baseline separation of each family of the analytes (neutral parabens, amphoteric sulfonamides and acidic benzoic acids) was obtained in less than 6 min with a resolution (Rs) of 2.79~9.30, which sufficiently verified the rapid separation, high resolution and wide application range of the TpBD COF immobilized capillary, and further revealed this strategy of fabricating COF to capillary column to show great promise in capillary electrochromatography