5,871 research outputs found

    Characterization of spatio-temporal epidural event-related potentials for mouse models of psychiatric disorders.

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    Distinctive features in sensory event-related potentials (ERPs) are endophenotypic biomarkers of psychiatric disorders, widely studied using electroencephalographic (EEG) methods in humans and model animals. Despite the popularity and unique significance of the mouse as a model species in basic research, existing EEG methods applicable to mice are far less powerful than those available for humans and large animals. We developed a new method for multi-channel epidural ERP characterization in behaving mice with high precision, reliability and convenience and report an application to time-domain ERP feature characterization of the Sp4 hypomorphic mouse model for schizophrenia. Compared to previous methods, our spatio-temporal ERP measurement robustly improved the resolving power of key signatures characteristic of the disease model. The high performance and low cost of this technique makes it suitable for high-throughput behavioral and pharmacological studies

    Casimir effect with a helix torus boundary condition

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    We use the generalized Chowla-Selberg formula to consider the Casimir effect of a scalar field with a helix torus boundary condition in the flat (D+1D+1)-dimensional spacetime. We obtain the exact results of the Casimir energy density and pressure for any DD for both massless and massive scalar fields. The numerical calculation indicates that once the topology of spacetime is fixed, the ratio of the sizes of the helix will be a decisive factor. There is a critical value rcritr_{crit} of the ratio rr of the lengths at which the pressure vanishes. The pressure changes from negative to positive as the ratio rr passes through rcritr_{crit} increasingly. In the massive case, we find the pressure tends to the result of massless field when the mass approaches zero. Furthermore, there is another critical ratio of the lengths rcrit′r_{crit}^{\prime} and the pressure is independent of the mass at r=rcrit′r=r_{crit}^{\prime} in the D=3 case.Comment: 11 pages, 3 figures, to be published in Mod. Phys. Lett.

    Doping dependance of the spin resonance peak in bilayer high-TcT_c superconductors

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    Motivated by a recent experiment on the bilayer Y1−x_{1-x}Cax_{x}Ba2_2Cu3_3Oy_y superconductor and based on a bilayer t−Jt-J model, we calculate the spin susceptibility at different doping densities in the even and odd channels in a bilayer system. It is found that the intensity of the resonance peak in the even channel is much weaker than that in the odd one, with the resonance position being at a higher frequency. While this difference decreases as the doping increases, and both the position and amplitude of the resonance peaks in the two channels are very similar in the deeply overdoped sample. Moreover, the resonance frequency in the odd channel is found to be linear with the critical temperature TcT_c, while the resonance frequency increases as doping decreases in the even channel and tends to saturate at the underdoped sample. We elaborate the results based on the Fermi surface topology and the d-wave superconductivity.Comment: 6 pages, 5 figure

    Preventing eternality in phantom inflation

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    We have investigated the necessary conditions that prevent phantom inflation from being eternal. Allowing additionally for a nonminimal coupling between the phantom field and gravity, we present the slow-climb requirements, perform an analysis of the fluctuations, and finally we extract the overall conditions that are necessary in order to prevent eternality. Furthermore, we verify our results by solving explicitly the cosmological equations in a simple example of an exponential potential, formulating the classical motion plus the stochastic effect of the fluctuations through Langevin equations. Our analysis shows that phantom inflation can be finite without the need of additional exotic mechanisms.Comment: 8 pages, V2 references added. V3 version published in Phys. Rev.

    Latest Observational Constraints to the Ghost Dark Energy Model by Using Markov Chain Monte Carlo Approach

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    Recently, the vacuum energy of the QCD ghost in a time-dependent background is proposed as a kind of dark energy candidate to explain the acceleration of the universe. In this model, the energy density of the dark energy is proportional to the Hubble parameter HH, which is the Hawking temperature on the Hubble horizon of the Friedmann-Robertson-Walker (FRW) universe. In this paper, we perform a constraint on the ghost dark energy model with and without bulk viscosity, by using the Markov Chain Monte Carlo (MCMC) method and the combined latest observational data from the type Ia supernova compilations including Union2.1(580) and Union2(557), cosmic microwave background, baryon acoustic oscillation, and the observational Hubble parameter data.Comment: 12 pages, 4 figure

    Magnetic transitions and magnetodielectric effect in the antiferromagnet SrNdFeO4_4

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    We investigated the magnetic phase diagram of single crystals of SrNdFeO4_{4} by measuring the magnetic properties, the specific heat and the dielectric permittivity. The system has two magnetically active ions, Fe3+^{3+} and Nd3+^{3+}. The Fe3+^{3+} spins are antiferromagnetically ordered below 360 K with the moments lying in the ab-plane, and undergo a reorientation transition at about 35-37 K to an antiferromagnetic order with the moments along the c-axis. A short-range, antiferromagnetic ordering of Nd3+^{3+} along the c-axis was attributed to the reorientation of Fe3+^{3+} followed by a long-range ordering at lower temperature [S. Oyama {\it et al.} J. Phys.: Condens. Matter. {\bf 16}, 1823 (2004)]. At low temperatures and magnetic fields above 8 T, the Nd3+^{3+} moments are completely spin-polarized. The dielectric permittivity also shows anomalies associated with spin configuration changes, indicating that this compound has considerable coupling between spin and lattice. A possible magnetic structure is proposed to explain the results.Comment: 8 pages, 10 figures, submitted to PR

    Geographical effects on epidemic spreading in scale-free networks

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    Many real networks are embedded in a metric space: the interactions among individuals depend on their spatial distances and usually take place among their nearest neighbors. In this paper, we introduce a modified susceptible-infected-susceptible (SIS) model to study geographical effects on the spread of diseases by assuming that the probability of a healthy individual infected by an infectious one is inversely proportional to the Euclidean distance between them. It is found that geography plays a more important role than hubs in disease spreading: the more geographically constrained the network is, the more highly the epidemic prevails.Comment: 4 pages, 5 figure
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