30 research outputs found

    Why People Are Willing to Share More Knowledge than Required

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    Knowledge sharing is critical for modern organizations. Besides in-role knowledge sharing, there exists knowledge sharing beyond one’s role, which is called extra-role knowledge sharing. This study investigates the antecedents of the extra-role knowledge sharing from the perspective of organizational citizenship behavior (OCB). Previous studies on OCB and works on knowledge sharing were reviewed to develop a model explaining the factors behind extra- role knowledge sharing. Willingness to help that is hypothesized to be influenced by procedural justice, job satisfaction, and employee personality (extraversion and agreeableness) is believed to influence extra- role knowledge sharing. Empirical data confirmed most of the hypotheses of this study

    Altered intestinal microbiota enhances adenoid hypertrophy by disrupting the immune balance

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    IntroductionAdenoid hypertrophy (AH) is a common upper respiratory disorder in children. Disturbances of gut microbiota have been implicated in AH. However, the interplay of alteration of gut microbiome and enlarged adenoids remains elusive.Methods119 AH children and 100 healthy controls were recruited, and microbiome profiling of fecal samples in participants was performed using 16S rRNA gene sequencing. Fecal microbiome transplantation (FMT) was conducted to verify the effects of gut microbiota on immune response in mice.ResultsIn AH individuals, only a slight decrease of diversity in bacterial community was found, while significant changes of microbial composition were observed between these two groups. Compared with HCs, decreased abundances of Akkermansia, Oscillospiraceae and Eubacterium coprostanoligenes genera and increased abundances of Bacteroides, Faecalibacterium, Ruminococcus gnavus genera were revealed in AH patients. The abundance of Bacteroides remained stable with age in AH children. Notably, a microbial marker panel of 8 OTUs were identified, which discriminated AH from HC individuals with an area under the curve (AUC) of 0.9851 in the discovery set, and verified in the geographically different validation set, achieving an AUC of 0.9782. Furthermore, transfer of mice with fecal microbiota from AH patients dramatically reduced the proportion of Treg subsets within peripheral blood and nasal-associated lymphoid tissue (NALT) and promoted the expansion of Th2 cells in NALT.ConclusionThese findings highlight the effect of the altered gut microbiota in the AH pathogenesis

    Acoustic Emission <i>b</i> Value Characteristics of Granite under True Triaxial Stress

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    The acoustic emission b value is an important and widely used parameter for the early prediction of rock fractures. In this study, five groups of true triaxial compression tests were conducted on granite specimens to analyze changes in b value during the process of rock failure, and to investigate the b value characteristics of acoustic emission events. First, the acoustic emission events that simultaneously triggered at least four sensors were located using P-wave arrivals and sensor coordinates. Then, considering various intervals of acoustic emission event counts, stress magnitude, and stress proportion, b values were calculated using the values of the maximum amplitude, average amplitude, maximum absolute energy, and average absolute energy of the acoustic emission events. In addition, the goodness of the fitting curves was used to evaluate the fitting reliability of the b values. The results indicated higher accuracy of b value when calculated using the average amplitude setting for intervals of acoustic emission event counts of 200 or greater, stress magnitude of 20 MPa or greater, and stress proportion of 10% or greater. Moreover, the interval of event counts of 200 is suggested as a window parameter for b value calculations, and the b values are observed to exhibit a decreasing trend before fracture for more than 80% of the specimens. Furthermore, the b value tends to decrease with an increase in confining pressure. Thus, the b value can be used as an indicator for validating the stress concentration area, including magnitudes and accumulative probability density distribution of events, which is a beneficial complement to clarifying precursor information of rock mass instability

    Photofragment translational spectroscopy of ICl near 304 and 280 nm: Observation of an intense hot band effect

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    The photodissociation dynamics of ICl has been studied near 304 and 280 nm on a simple miniature time of flight (mini-TOF) photofragment translational spectrometer with a short pulse of a weak acceleration field. An intense hot band effect was observed. Many small peaks were resolved in each photofragment translational spectrum (PTS). Based on simulations, the principal peaks were assigned not only to the different photodissociation channels (1) I + Cl, (2) I + Cl*, (3) I* + Cl, or (4) I* + Cl*, but also to the different chlorine isotopes (Cl-35 and Cl-37). Moreover, some extra peaks showed the existence of an intense hot band effect from vibrationally excited ICl molecules, though only a few percent of ICl molecules remained in the vibrationally excited states in our supersonic molecular beam. Based on the spectra near 304 nm, the quantum yield I broken vertical bar of each channel, the curve crossing, and the branching fraction sigma from each transition state were determined

    Vibrational state distributions following the photodissociation of CF3I near 304 nm

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    The photodissociation of CF3I has been studied near 304 nm. The partially resolved vibrational peaks in the I* and I channels reveal that the nu(2) umbrella mode of CF3 is preferentially excited. Besides, in the I* channel, the extra vibrational peaks assigned to the umbrella mode of CF3 from the hot band nu(3)' 1, 2 states of CF3I are also partially resolved. The E-int/E-avl shows a gradual increase as the state of CF3I changes from nu(3)' = 0 to nu(3)' = 2. The anisotropy parameter is also obtained and discussed with the interrelation of the (3)Q(1), (3)Q(0), and (1)Q(1) potential energy surfaces. (C) 2010 Elsevier B. V. All rights reserved

    Time Course Transcriptome Changes in <i>Shewanella algae</i> in Response to Salt Stress

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    <div><p><i>Shewanella algae</i>, which produces tetrodotoxin and exists in various seafoods, can cause human diseases, such as spondylodiscitis and bloody diarrhea. In the present study, we focused on the temporal, dynamic process in salt-stressed <i>S. algae</i> by monitoring the gene transcript levels at different time points after high salt exposure. Transcript changes in amino acid metabolism, carbohydrate metabolism, energy metabolism, membrane transport, regulatory functions, and cellular signaling were found to be important for the high salt response in <i>S. alga</i>e. The most common strategies used by bacteria to survive and grow in high salt environments, such as Na<sup>+</sup> efflux, K<sup>+</sup> uptake, glutamate transport and biosynthesis, and the accumulation of compatible solutes, were also observed in <i>S. algae.</i> In particular, genes involved in peptidoglycan biosynthesis and DNA repair were highly and steadily up-regulated, accompanied by rapid and instantaneous enhancement of the transcription of large- and small-ribosome subunits, which suggested that the structural changes in the cell wall and some stressful responses occurred in <i>S. algae</i>. Furthermore, the transcription of genes involved in the tricarboxylic acid (TCA) cycle and the glycolytic pathway was decreased, whereas the transcription of genes involved in anaerobic respiration was increased. These results, demonstrating the multi-pathway reactions of <i>S. algae</i> in response to salt stress, increase our understanding of the microbial stress response mechanisms.</p></div

    Photofragment Translational Spectroscopy of n

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    Photofragment translational spectroscopy of n-C3H7I and i-C3H7I near 280 and 304 nm

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    The photodissociation dynamics of propyl iodides n-C3H7I and i-C3H7I near 280 and 304 nm has been investigated with our mini-TOF photofragment translational spectrometer. When a single laser is applied for both the photodissociation of parent molecules and the REMPI of I atom photofragments, the TOF spectra of photofragments I*('P-1/2) and I (P-2(3/2)) are obtained at four different wavelengths for these two iodides. For n-C3H7I, some small vibrational peaks are partially resolved (with separation of similar to 522 cm(-1), corresponding to the RCH2 deformation frequency of the fragment n-C3H7) at 281.73, 279.71, and 304.67 nm. These results show that the RCH2 deformation is mostly excited. For i-C3H7I, we obtain some partially resolved vibrational peaks (with separation of similar to 352 cm(-1), corresponding to the HC(CH3)(2) out-of-plane bending frequency of the fragment i-C3H7) at 281.73 nm only. For n-C3H7I, the partitioning values of the available energy (E) over bar (int)/E-avl are 0.48 at 281.73 nm and 0.49 at 304.02 nm for the I* channel, and 0.52 at both 279.71 and 304.67 nm for the I channel. These energy partitioning values are comparable with the previous results at different wavelengths in the literature. For i-C3H7I, the (E) over bar (int)/E-avl values are 0.61 at 281.73 nm, 0.65 at 304.02 nm for the I* channel, and 0.62 at 279.71 nm, 0.49 at 304.67 nm for the I channel. The potential-energy-surface crossing and the beta values have also been discussed

    Protective Effects of Elaeagnus angustifolia Leaf Extract against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart

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    The purpose of this study is to clarify the cardioprotective property of the aqueous extract of Elaeagnus angustifolia L. leaf (EA) against myocardial ischemia/reperfusion injury in isolated rat heart. The myocardial ischemia/reperfusion (I/R) injury model of isolated rat heart was set up by the use of improved Langendorff retrograde perfusion technology. Compared with the ischemia/reperfusion (I/R) group, the aqueous extract of Elaeagnus angustifolia L. leaf (0.5 mg/mL, 1.0 mg/mL) pretreatment markedly improved the coronary flow (CF) and raised left ventricular developed pressure (LVDP) and maximum rise/down velocity (±dp/dtmax). The infarct size of the EA-treated hearts was smaller than that of I/R group. After treatment with EA, the superoxide dismutase (SOD) activity increased; malondialdehyde (MDA) and protein carbonyl content reduced more obviously (P<0.01) than that of I/R injury myocardial tissue. Conclusion. Results from the present study showed that the aqueous extract of Elaeagnus angustifolia L. leaf has obvious protective effects on myocardial I/R injury, which may be related to the improvement of myocardial oxidative stress states
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