Spin-current Seebeck effect in quantum dot systems

We first bring up the concept of spin-current Seebeck effect based on a recent experiment [Nat. Phys. {\bf 8}, 313 (2012)], and investigate the spin-current Seebeck effect in quantum dot (QD) systems. Our results show that the spin-current Seebeck coefficient $S$ is sensitive to different polarization states of QD, and therefore can be used to detect the polarization state of QD and monitor the transitions between different polarization states of QD. The intradot Coulomb interaction can greatly enhance the $S$ due to the stronger polarization of QD. By using the parameters for a typical QD, we demonstrate that the maximum $S$ can be enhanced by a factor of 80. On the other hand, for a QD whose Coulomb interaction is negligible, we show that one can still obtain a large $S$ by applying an external magnetic field.Comment: 6 pages, 8 figure

Management of intractable epistaxis in patients who received radiation therapy for nasopharyngeal carcinoma

To report clinical manifestations, bleeding point localization, and outcomes of management in 16 patients with 16 instances of intractable epistaxis after radiation therapy for nasopharyngeal carcinoma. Retrospective chart review of 16 patients with nasopharyngeal carcinoma (mean age 52.06 ± 14.37 years) with 16 instances of intractable epistaxis during the past 5 years, whose diagnosis was confirmed by angiography (n = 10) or MRI/CT imaging studies and clinical manifestations (n = 6). The mean radiation dose to the affected carotid artery was 101.37 ± 34.85 Gy. Bleeding points were detected in the internal carotid artery (n = 8) or external carotid artery (n = 8). Detachable balloons were used in one affected artery for vascular occlusion; six were treated using an absorbable gelatin sponge (n = 4) or microcoils (diameter 1 mm) (n = 2). Endovascular embolization was successful in seven radiation carotid blowout syndromes with cessation of hemorrhage. One patient underwent external carotid artery ligation and one patient recovered without treatment. The clinical follow-up was 3 months. Therapeutic endovascular embolization of intractable epistaxis is both efficient and safe. It should be considered as the primary treatment modality in intractable epistaxis of nasopharyngeal carcinoma

Topological insulator: a new quantized spin Hall resistance robust to dephasing

The influence of dephasing on the quantum spin Hall effect (QSHE) is studied. In the absence of dephasing, the longitudinal resistance in a QSHE system exhibits the quantum plateaus. We find that these quantum plateaus are robust against the normal dephasing but fragile with the spin dephasing. Thus, these quantum plateaus only survive in mesoscopic samples. Moreover, the longitudinal resistance increases linearly with the sample length but is insensitive to the sample width. These characters are in excellent agreement with the recent experimental results [science {\bf 318}, 766 (2007)]. In addition, we define a new spin Hall resistance that also exhibits quantum plateaus. In particular, these plateaus are robust against any type of dephasing and therefore, survive in macroscopic samples and better reflect the topological nature of QSHE.Comment: 4 pages, 5 figure

Research And Implementation Of Drug Target Interaction Confidence Measurement Method Based On Causal Intervention

The identification and discovery of drug-target Interaction (DTI) is an important step in the field of Drug research and development, which can help scientists discover new drugs and accelerate the development process. KnowledgeGraph and the related knowledge graph Embedding (KGE) model develop rapidly and show good performance in the field of drug discovery in recent years. In the task of drug target identification, the lack of authenticity and accuracy of the model will lead to the increase of misjudgment rate and the low efficiency of drug development. To solve the above problems, this study focused on the problem of drug target link prediction with knowledge mapping as the core technology, and adopted the confidence measurement method based on causal intervention to measure the triplet score, so as to improve the accuracy of drug target interaction prediction model. By comparing with the traditional Softmax and Sigmod confidence measurement methods on different KGE models, the results show that the confidence measurement method based on causal intervention can effectively improve the accuracy of DTI link prediction, especially for high-precision models. The predicted results are more conducive to guiding the design and development of followup experiments of drug development, so as to improve the efficiency of drug development.Comment: 8 pages,11 figure