Mutation pattern is an influential factor on functional mutation rates in cancer

Additional file 1. Supplementary figures

Overview of Academic Studies on Smart Care for the Elderly and Comprehensive Solution Design

Due to historical reasons and urbanization progress, demographic development change has promoted China to enter an aging society and the elders’ demand for medical care and health care has increased rapidly. Meanwhile, the rapid development of information technology is driving the “Smart Care for the Elderly” model which is based on the Internet and regards the internet of things as the medium which has gradually developed into a complete a system, and a series of solutions have been formed. This paper started with the analysis of China’s elderly population status quo, combed academic studies on domestic and foreign “Smart Care for the Elderly” and applications in recent fifteen years and explored how to build a comprehensive “Smart Care for Elderly” solution with improved functions which incorporates such key elements as information technology and social sciences

A Comprehensive Empirical Investigation on Failure Clustering in Parallel Debugging

The clustering technique has attracted a lot of attention as a promising strategy for parallel debugging in multi-fault scenarios, this heuristic approach (i.e., failure indexing or fault isolation) enables developers to perform multiple debugging tasks simultaneously through dividing failed test cases into several disjoint groups. When using statement ranking representation to model failures for better clustering, several factors influence clustering effectiveness, including the risk evaluation formula (REF), the number of faults (NOF), the fault type (FT), and the number of successful test cases paired with one individual failed test case (NSP1F). In this paper, we present the first comprehensive empirical study of how these four factors influence clustering effectiveness. We conduct extensive controlled experiments on 1060 faulty versions of 228 simulated faults and 141 real faults, and the results reveal that: 1) GP19 is highly competitive across all REFs, 2) clustering effectiveness decreases as NOF increases, 3) higher clustering effectiveness is easier to achieve when a program contains only predicate faults, and 4) clustering effectiveness remains when the scale of NSP1F is reduced to 20%