1 research outputs found
Facile Preparation of Mussel-Inspired Polyurethane Hydrogel and Its Rapid Curing Behavior
A facile
method was found to incorporate a mussel-inspired adhesive
moiety into synthetic polymers, and mussel mimetic polyurethanes were
developed as adhesive hydrogels. In these polymers, a urethane backbone
was substituted for the polyamide chain of mussel adhesive proteins,
and dopamine was appended to mimic the adhesive moiety of adhesive
proteins. A series of mussel mimetic polyurethanes were created through
a step-growth polymerization based on hexamethylene diisocyanate as
a hard segment, PEG having different molecular weights as a soft segment,
and lysine-dopamine as a chain extender. Upon a treatment with Fe<sup>3+</sup>, the aqueous mussel mimetic polyurethane solutions can be
triggered by pH adjustment to form adhesive hydrogels instantaneously;
these materials can be used as injectable adhesive hydrogels. Upon
a treatment with NaIO<sub>4</sub>, the mussel mimetic polyurethane
solutions can be cured in a controllable period of time. The successful
combination of the unique mussel-inspired adhesive moiety with a tunable
polyurethane structure can result in a new kind of mussel-inspired
adhesive polymers