86 research outputs found
NSOTree: Neural Survival Oblique Tree
Survival analysis is a statistical method employed to scrutinize the duration
until a specific event of interest transpires, known as time-to-event
information characterized by censorship. Recently, deep learning-based methods
have dominated this field due to their representational capacity and
state-of-the-art performance. However, the black-box nature of the deep neural
network hinders its interpretability, which is desired in real-world survival
applications but has been largely neglected by previous works. In contrast,
conventional tree-based methods are advantageous with respect to
interpretability, while consistently grappling with an inability to approximate
the global optima due to greedy expansion. In this paper, we leverage the
strengths of both neural networks and tree-based methods, capitalizing on their
ability to approximate intricate functions while maintaining interpretability.
To this end, we propose a Neural Survival Oblique Tree (NSOTree) for survival
analysis. Specifically, the NSOTree was derived from the ReLU network and can
be easily incorporated into existing survival models in a plug-and-play
fashion. Evaluations on both simulated and real survival datasets demonstrated
the effectiveness of the proposed method in terms of performance and
interpretability.Comment: 12 page
Reduction of Transmitted Information Using Similarities between Range Blocks in Fractal Image Coding
Fractal image coding uses the similarities between the best matching domain blocks and range blocks to reconstruct image. In the transmitted information, the information about the best matching domain blocks occupies a large percentage, so the reduction of information about the best matching domain blocks is the most effective method to reduce the quality of transmitted information. On the other hand, there are similarities between range blocks from each other. So, when range blocks are similar enough, we can reconstruct a range block by its similar range block, in other words, we can use the same domain block as their best matching domain block between similar range blocks. In this paper, we propose a method using similarities between the range blocks to reduce the position and affine information of the best matching domain blocks by sharing the same best matching domain block between similar range blocks.Fourth International Conference on Image and Graphics (ICIG 2007), Chengdu 22.-24.8.200
Do radioiodine-avid lymph nodes from differentiated thyroid cancer on the initial posttherapy scan need repeated 131I therapy?
BackgroundResidual/recurrent lymph node metastase (LNM) is often found after differentiated thyroid cancer (DTC) surgery. This study aimed to investigate whether patients complicated with radioiodine-avid (131I+) lymph nodes from DTC on the initial posttherapy scan (PTS) need repeated 131I therapy.MethodsFrom June 2013 to August 2022, DTC patients with 131I+ lymph nodes on the initial PTS who received at least two cycles of 131I therapy were retrospectively enrolled. They were divided into a complete response (CR) group and an incomplete response (IR) group according to their response to the initial 131I therapy based on the 2015 American Thyroid Association (ATA) guidelines.ResultsA total of 170 DTC patients with 131I+ lymph nodes on the initial PTS were included; 42/170 (24.7%) patients were classified into the CR group and 128/170 (75.9%) were classified into the IR group according to their response to the initial 131I therapy. None of the 42 CR patients had disease progression at the subsequent follow-up, and 37/170 (21.8%) IR patients improved after repeated therapy. Univariate analysis showed that N stage (P=0.002), stimulated thyroglobulin (sTg) level before initial 131I therapy (P<0.001), LNM size (P<0.001), number of total residual/recurrent LNM (P=0.021), radioiodine-nonavid (131I-) LNM (P=0.002) and ultrasound features (P<0.001) were related to the initial treatment response. On multivariate analysis, sTg level (OR=1.186, P<0.001) and LNM size (OR=1.533, P=0.004) were independent risk factors for IR after initial 131I therapy. The optimal sTg level and LNM size cutoff value for predicting the treatment response after initial 131I therapy were 18.2 µg/l and 5mm.ConclusionThis study suggested that approximately one-quarter of patients with 131I+ lymph nodes on initial PTS, especially those with N0 or N1a stage, lower sTg level, smaller LNM size, ≤2 residual/recurrent LNMs, negative ultrasound features and no 131I- LNM, remain stable after one cycle of 131I therapy and do not need repeated therapy
AhNRAMP1 Enhances Manganese and Zinc Uptake in Plants
Manganese (Mn) and zinc (Zn) play essential roles in plants. Members of the natural resistance-associated macrophage protein (NRAMP) family transport divalent metal ions. In this research, the function of peanut (Arachis hypogaea L.) AhNRAMP1 in transporting Mn and Zn, as well as its potential for iron(Fe) and Zn biofortification was examined. AhNRAMP1 transcription was strongly induced by Mn- or Zn-deficiency in roots and stems of peanut. Yeast complementation assays suggested that AhNRAMP1 encoded a functional Mn and Zn transporter. Exogenous expression of AhNRAMP1 in tobacco and rice enhanced Mn or Zn concentrations, improving tolerance to Mn or Zn deficiency. With higher Mn concentration, transgenic plants exhibited inhibited growth under Mn excess condition; similar results were obtained under excessive Zn treatment. AhNRAMP1 expression increased biomass in transgenic tobacco and rice, as well as yield in transgenic rice grown on calcareous soil. Compared with non-transformed (NT) plants, Fe and Zn concentrations were elevated whereas concentrations of Mn, copper (Cu), and cadmium (Cd) were not enhanced. These results revealed that AhNRAMP1 contributes to Mn and Zn transport in plants and may be a candidate gene for Fe and Zn biofortification
One-Loop Factorization of the Nucleon g_2-Structure Function in the Non-Singlet Case
We consider the one-loop factorization of the simplest twist-three process:
inclusive deep-inelastic scattering of longitudinally-polarized leptons on a
transversely-polarized nucleon target. By studying the Compton amplitudes for
certain quark and gluon states at one loop, we find the coefficient functions
for the non-singlet twist-three distributions in the factorization formula of
g_2(x_B,Q^2). The result marks the first step towards a next-to-leading order
(NLO) formalism for this transverse-spin-dependent structure function of the
nucleon.Comment: 14 pages, revtex4, four figures included, minor change
Chemotherapy combined with radiotherapy can benefit more unresectable HCC patients with portal and/or hepatic vein invasion: a retrospective analysis of the SEER database
BackgroundThe purpose of this study is to evaluate the effects of chemotherapy and radiotherapy on the prognosis of unresectable HCC patients with portal and/or hepatic vein invasion.MethodsA retrospective analysis of unresectable HCC patients with portal and/or hepatic vein invasion registered in the Surveillance, Epidemiology, End Results (SEER) database was performed. The propensity score-matching (PSM) method was used to balance differences between groups. Overall survival (OS) and cancer-specific survival (CSS) were the interesting endpoints. OS was calculated from the date of diagnosis to the date of death caused by any cause or the last follow-up. CSS was defined as the interval between the date of diagnosis and date of death due only to HCC or last follow-up. OS and CSS were analyzed by using Kaplan-Meier analysis, Cox proportional hazards model, and Fine-Gray competing-risk model.ResultsA total of 2,614 patients were included. 50.2% patients received chemotherapy or radiotherapy and 7.5% patients received both chemotherapy and radiotherapy. Compared to the untreated group, chemotherapy or radiotherapy (COR) (HR = 0.538, 95% CI 0.495-0.585, p < 0.001) and chemotherapy and radiotherapy (CAR) (HR = 0.371, 95% CI 0.316-0.436, p < 0.001) showed better OS. In the COR group, Cox analysis results showed AFP, tumor size, N stage and M stage were independent risk factor of OS. Competing-risk analysis results showed AFP, tumor size and M stage were independent risk factor of CSS. In the CAR group, AFP and M stage were independent risk factors of OS. Competing-risk analysis results showed M stage were independent risk factor of CSS. Kaplan Meier analysis showed chemotherapy combined with radiotherapy significantly improves OS (10.0 vs. 5.0 months, p < 0.001) and CSS (10.0 vs. 6.0 months, p = 0.006) than monotherapy.ConclusionAFP positive and distant metastasis are the main risk factors affecting OS and CSS of unresectable HCC patients with portal and/or hepatic vein invasion. Chemotherapy combined with radiotherapy significantly improves OS and CSS of unresectable HCC patients with portal and/or hepatic vein invasion
CatNorth: An Improved Gaia DR3 Quasar Candidate Catalog with Pan-STARRS1 and CatWISE
A complete and pure sample of quasars with accurate redshifts is crucial for
quasar studies and cosmology. In this paper, we present CatNorth, an improved
Gaia DR3 quasar candidate catalog with more than 1.5 million sources in the
3 sky built with data from Gaia, Pan-STARRS1, and CatWISE2020. The XGBoost
algorithm is used to reclassify the original Gaia DR3 quasar candidates as
stars, galaxies, and quasars. To construct training/validation datasets for the
classification, we carefully built two different master stellar samples in
addition to the spectroscopic galaxy and quasar samples. An ensemble
classification model is obtained by averaging two XGBoost classifiers trained
with different master stellar samples. Using a probability threshold of
in our ensemble classification model and an
additional cut on the logarithmic probability density of zero proper motion, we
retrieved 1,545,514 reliable quasar candidates from the parent Gaia DR3 quasar
candidate catalog. We provide photometric redshifts for all candidates with an
ensemble regression model. For a subset of 89,100 candidates, accurate
spectroscopic redshifts are estimated with the Convolutional Neural Network
from the Gaia BP/RP spectra. The CatNorth catalog has a high purity of > 90%
while maintaining high completeness, which is an ideal sample to understand the
quasar population and its statistical properties. The CatNorth catalog is used
as the main source of input catalog for the LAMOST phase III quasar survey,
which is expected to build a highly complete sample of bright quasars with .Comment: 24 pages, 13 figures, submitted to AAS journals. Table 4 (The
CatNorth quasar candidate catalog) is available at
https://nadc.china-vo.org/res/r101313
The 30–50-Day Intraseasonal Oscillation of SST and Precipitation in the South Tropical Indian Ocean
The Sea Surface Temperature (SST) in the South Tropical Indian Ocean (STIO) displays significant intraseasonal oscillation (ISO) in two regions. A striking 30–50-day ISO found over the east of thermocline ridge (Region A, 80–90° E, 6–12° S), as identified by the Empirical Mode Decomposition (EMD) method, is distinguished from the SST signature over the thermocline ridge (Region B, 52.5–65° E, 6–13° S). The 30–50-day ISO of SST in the Region A is active in March–May (MAM) and suppressed in September–November (SON). Meanwhile, a 30–50-day ISO of precipitation correlates with the SST over the Region A. SST leads precipitation by 10 days, implying a pronounced ocean–atmosphere interaction at the intraseasonal timescale, especially the oceanic feedback to the atmosphere during Madden–Julian Oscillation (MJO) events. Analysis on mechanism of the ISO manifests heat fluxes are critical to the development of the intraseasonal SST variability. The local thermocline in Region A, as the shallowest in MAM and the thickest in SON, is likely to modulate the strength of ISO and contribute to its sustainability. It suggests that thermocline plays a more important role in Region A than in Region B, leading to the difference between the two regions
Unregulated Emissions from Natural Gas Taxi Based on IVE Model
Emissions from motor vehicles have gained the attention of government agencies. To alleviate air pollution and reduce the petroleum demand from vehicles in China, the policy of “oil to gas” was vigorously carried out. Qingdao began to promote the use of natural gas vehicles (NGVs) in 2003. By the end of 2016, there were 9460 natural gas (NG) taxis in Qingdao, which accounted for 80% of the total taxis. An understanding of policy implementation for emission reductions is required. Experiments to obtain the taxi driving conditions and local parameters were investigated and an international vehicle emissions (IVE) localization model was established. Combined with vehicle mass analysis system (VMAS) experiments, the IVE localization model was amended and included the taxi pollutant emission factors. The result indicates that annual total carbon monoxide (CO) emissions from actual taxis are 6411.87 t, carbureted hydrogen (HC) emissions are 124.85 t, nitrogen oxide (NOx) emissions are 1397.44 t and particulate matter (PM) emissions are 8.9 t. When the taxis are running on pure natural gas, the annual emissions of CO, HC, NOx and PM are 4942.3 t, 48.15 t, 1496.01 t and 5.13 t, respectively. Unregulated emissions of annual total formaldehydes, benzene, acetaldehyde, 1,3-butadience emissions from an actual taxi are 65.99 t, 4.68 t, 1.04 t and 8.83 t. When the taxi is running on pure natural gas, the above unregulated emissions are 12.11 t, 1.27 t, 1.5 t and 0.02 t, respectively
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