MDS-MSC reduce IL-12 secretion of monocyte-derived DCs.

<p>DCs <b>(1×10⁶)</b> obtained from monocytes after 7 days of induction with GM-CSF plus IL-4 were stimulated by LPS for an additional 48 hours with or without MSC coculture, and then cell-free supernatants were collected and quantified by ELISA for IL-12 production. Results are expressed as mean±SD of triplicates of 5 separate experiments. *P≤0.05.</p

MDS-MSC inhibit the capability of inducing T-cell response in MLR of monocyte-derived DCs.

<p>mDCs <b>(1×10⁵)</b> were irradiated and used to induce allogeneic T cells (10⁶ responder cells/well) with or without MSC <b>(1×10⁵)</b> in the MLR culture. After culture for 5 days, T-cell proliferation was evaluated by adding 3H-thymidine to each well 18 h before the cultures were terminated. Results are expressed as mean±SD of triplicates of 5 separate experiments. *P≤0.05.</p

Additional file 2: Table S1. of Chidamide in relapsed or refractory peripheral T cell lymphoma: a multicenter real-world study in China

Patients’ baseline characteristics (DOCX 16 kb

Additional file 1: of Chidamide in relapsed or refractory peripheral T cell lymphoma: a multicenter real-world study in China

Methods (DOCX 16 kb