1 research outputs found
Asymmetric Synthesis and Absolute Configuration of Streptophenazine G
The asymmetric synthesis of the antibacterial natural
product,
streptophenazine G, has been achieved by employing asymmetric alkylation
and asymmetric aldol reactions using chiral oxazolidinones as the
key steps. The originally proposed structure for streptophenazine
G has been revised, and its absolute configuration has been determined
to be 1′<i>S</i>,2′<i>R</i>,6′<i>S</i>. The asymmetric total synthesis of 6′-<i>epi</i>-streptophenazine G is also described