1 research outputs found
MolProphet: A One-Stop, General Purpose, and AI-Based Platform for the Early Stages of Drug Discovery
Artificial intelligence
(AI) is an effective tool to
accelerate
drug discovery and cut costs in discovery processes. Many successful
AI applications are reported in the early stages of small molecule
drug discovery. However, most of those applications require a deep
understanding of software and hardware, and focus on a single field
that implies data normalization and transfer between those applications
is still a challenge for normal users. It usually limits the application
of AI in drug discovery. Here, based on a series of robust models,
we formed a one-stop, general purpose, and AI-based drug discovery
platform, MolProphet, to provide complete functionalities in the early
stages of small molecule drug discovery, including AI-based target
pocket prediction, hit discovery and lead optimization, and compound
targeting, as well as abundant analyzing tools to check the results.
MolProphet is an accessible and user-friendly web-based platform that
is fully designed according to the practices in the drug discovery
industry. The molecule screened, generated, or optimized by the MolProphet
is purchasable and synthesizable at low cost but with good drug-likeness.
More than 400 users from industry and academia have used MolProphet
in their work. We hope this platform can provide a powerful solution
to assist each normal researcher in drug design and related research
areas. It is available for everyone at https://www.molprophet.com/