Jadad Scale for Randomized Controlled Trials (RCTs).

<p>Jadad Scale for Randomized Controlled Trials (RCTs).</p

Forest plot showing the mean difference (MD) in tear film osmolarity (TFO) comparing small incision lenticule extraction (SMILE) with femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) at (A) one month and (B) six months postoperatively.

<p>CI = confidence interval; SD = standard deviation.</p

Dry Eye after Small Incision Lenticule Extraction (SMILE) versus Femtosecond Laser-Assisted in Situ Keratomileusis (FS-LASIK) for Myopia: A Meta-Analysis

<div><p>Purpose</p><p>To compare dry eye after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK (FS-LASIK) for correcting myopia.</p><p>Methods</p><p>CENTRAL, Embase and PubMed were searched in November 2016. All randomized controlled trials (RCTs) and prospective cohorts that compared dry eye after SMILE with FS-LASIK were selected.</p><p>Results</p><p>Five cohorts and one RCT were identified for comparing dry eye after SMILE (291 eyes) and FS-LASIK (277 eyes). The pooled results revealed that the SMILE and FS-LASIK groups did not differ significantly in terms of Schirmer’s I test (SIT) and tear film osmolarity (TFO) at any postoperative visits. By contrast, tear break up time (TBUT; <i>p</i> = 0.04 for one month, <i>p</i> < 0.001 for three months, and <i>p</i> = 0.02 for six months) and ocular surface disease index (OSDI; <i>p</i> < 0.001 for one month and three months, and <i>p</i> = 0.006 for six months) were significantly worse in the FS-LASIK group than in the SMILE group at follow-up. At six months postoperatively, TBUT and TFO values in both the SMILE and FS-LASIK groups and OSDI scores in the SMILE group returned to preoperative levels, but SIT values in both groups (<i>p</i> = 0.02 for the SMILE group and <i>p</i> < 0.001 for the FS-LASIK group) and OSDI in the FS-LASIK group (<i>p</i> < 0.001) were still statistically impaired.</p><p>Conclusion</p><p>Dry eye after both SMILE and FS-LASIK usually occurs transiently. SMILE does not show obvious superiority over FS-LASIK by exhibiting similar and acceptable objective parameters, and SMILE may have milder subjective symptoms.</p></div

Two New (3,6)-Connected MOFs with <i>eea</i> Topology and High CH₄ Uptake

Two new (3,6)-connected and <i>eea</i> topological MOFs without open metal sites, NJU-Bai30 and NJU-Bai31, from Cu-paddelwheel units and 5-[4′-(pyridin-4-yl)­phenyl]­isophthalic acid (L₁) and 5-[3′-amino-4′-(pyridin-4-yl)­phenyl]­isophthalic acid (L₂) have been synthesized, and interestingly, they exhibit relatively high surface area and large CH₄ adsorption uptake

Forest plot showing the mean difference (MD) of tear breakup time (TBUT) comparing small incision lenticule extraction (SMILE) with femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) (A) preoperatively and in postoperative visits at (B) one week, (C) one month, (D) three months and (E) six months. Forest plot showing the MD of TBUT in the (F) SMILE and (G) FS-LASIK groups at six months postoperatively compared with preoperatively.

<p>CI = confidence interval; SD = standard deviation.</p

Forest plot showing the mean difference (MD) in ocular surface disease index (OSDI) comparing small incision lenticule extraction (SMILE) with femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) (A) preoperatively and in postoperative visits at (B) one month, (C) three months and (D) six months. Forest plot showing the MD of OSDI in the (E) SMILE and (F) FS-LASIK groups at six months postoperatively compared with preoperatively.

<p>CI = confidence interval; SD = standard deviation.</p

Flow chart showing literature search strategy.

<p>LASIK = laser in situ keratomileusis; SMILE = small incision lenticule extraction; FLEx = femtosecond lenticule extraction; RCTs = randomized controlled trials. <i>From</i>: Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009). <i>P</i>referred <i>R</i>eporting <i>I</i>tems for <i>S</i>ystematic Reviews and <i>M</i>eta-<i>A</i>nalyses: The PRISMA Statement. PloS Med 6(7): e1000097. doi: <a href="http://dx.doi.org/10.1371/journal.pmed1000097" target="_blank">10.1371/journal.pmed1000097</a>.</p

Results of the examination of the forest plots (<i>p</i> value).

<p>Results of the examination of the forest plots (<i>p</i> value).</p

Newcastle–Ottawa Scale for Observational Studies (cohorts).

<p>Newcastle–Ottawa Scale for Observational Studies (cohorts).</p

Characteristics of Studies Included in the Meta-Analysis Comparing the Small Incision Lenticule Extraction (SMILE) and Femtosecond Laser-Assisted Laser in Situ Keratomileusis (FS-LASIK).

<p>Characteristics of Studies Included in the Meta-Analysis Comparing the Small Incision Lenticule Extraction (SMILE) and Femtosecond Laser-Assisted Laser in Situ Keratomileusis (FS-LASIK).</p