2,726 research outputs found

    Cyber security investigation for Raspberry Pi devices

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    Big Data on Cloud application is growing rapidly. When the cloud is attacked, the investigation relies on digital forensics evidence. This paper proposed the data collection via Raspberry Pi devices, in a healthcare situation. The significance of this work is that could be expanded into a digital device array that takes big data security issues into account. There are many potential impacts in health area. The field of Digital Forensics Science has been tagged as a reactive science by some who believe research and study in the field often arise as a result of the need to respond to event which brought about the needs for investigation; this work was carried as a proactive research that will add knowledge to the field of Digital Forensic Science. The Raspberry Pi is a cost-effective, pocket sized computer that has gained global recognition since its development in 2008; with the wide spread usage of the device for different computing purposes. Raspberry Pi can potentially be a cyber security device, which can relate with forensics investigation in the near future. This work has used a systematic approach to study the structure and operation of the device and has established security issues that the widespread usage of the device can pose, such as health or smart city. Furthermore, its evidential information applied in security will be useful in the event that the device becomes a subject of digital forensic investigation in the foreseeable future. In healthcare system, PII (personal identifiable information) is a very important issue. When Raspberry Pi plays a processor role, its security is vital; consequently, digital forensics investigation on the Raspberry Pies becomes necessary

    Anion-Peptide Adduct Formation and Decomposition As Studied by Fourier Transform Ion Cyclotron Resonance (FT-ICR) Mass Spectrometry

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    A new “best match” match model has been developed to account for adduct formation on multiply charged peptides observed in negative ion electrospray mass spectrometry. To obtain a stable adduct, the model necessitates an approximate matching of apparent gas-phase basicity (GBapp) of a given proton bearing site on the peptide with the gas-phase basicity (GB) of the anion attaching at that site. Evidence supporting the model is derived from the fact that singly charged adducts were only observed for lower GB anions: HSO4-, I-, CF3COO-. Ions that have medium GBs (NO3-, Br-, H2PO4-) only form adducts having -2 charge states, whereas Cl- (higher GB) can form adducts having -3 charge states. Hydrogen bonds are the main interactions pertinent to the “Best Match” model, however, ion-ion interactions formed between peptides ([Glu]Fibrinopeptide B, Angiotensin I or [Asn1,Val5]-Angiotensin II) and low GB anions (ClO4- or HSO4-) have been established by CID-MS/MS. Evidence for ion-ion interactions comes especially from product ions formed during the first dissociation step, where, in addition to the expected loss of the anion or neutral acid, other product ions that require covalent bond cleavage (i.e., H2O or NH3 loss) are also observed. In this study, the “Best Match” model is further supported by the decomposition behavior of adducts formed when Na+/H+ exchange has occurred on peptides. Na+/H+ exchanges were found to occur preferentially at higher acidity sites. Without any Na+/H+ exchange, F- and CH3COO- can hardly form observable adducts with [Glu]Fibrinopeptide B. However, after multiple Na+/H+ exchanges, F- and CH3COO- do form stable adducts. This phenomenon can be rationalized by considering that Na+ cations serve to “block” the highly acidic sites, thereby forcing them to remain overall neutral. This leaves the less acidic protons available to match with higher GB anions. According to the best match model, high GB anions will match with high GBapp sites on the peptide, whereas low GB anions will match with low GBapp peptide sites. High charge states readily augment GBapp of the peptide (through-space effect). Na+/H+ exchanges substantially decrease GBapp by neutralizing charged sites, while slightly increasing intrinsic GBs by the inductive effect

    Chunk-Based Bi-Scale Decoder for Neural Machine Translation

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    In typical neural machine translation~(NMT), the decoder generates a sentence word by word, packing all linguistic granularities in the same time-scale of RNN. In this paper, we propose a new type of decoder for NMT, which splits the decode state into two parts and updates them in two different time-scales. Specifically, we first predict a chunk time-scale state for phrasal modeling, on top of which multiple word time-scale states are generated. In this way, the target sentence is translated hierarchically from chunks to words, with information in different granularities being leveraged. Experiments show that our proposed model significantly improves the translation performance over the state-of-the-art NMT model.Comment: Accepted as a short paper by ACL 201

    Accurate Multi-physics Numerical Analysis of Particle Preconcentration Based on Ion Concentration Polarization

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    This paper studies mechanism of preconcentration of charged particles in a straight micro-channel embedded with permselective membranes, by numerically solving coupled transport equations of ions, charged particles and solvent fluid without any simplifying assumptions. It is demonstrated that trapping and preconcentration of charged particles are determined by the interplay between drag force from the electroosmotic fluid flow and the electrophoretic force applied trough the electric field. Several insightful characteristics are revealed, including the diverse dynamics of co-ions and counter ions, replacement of co-ions by focused particles, lowered ion concentrations in particle enriched zone, and enhanced electroosmotic pumping effect etc. Conditions for particles that may be concentrated are identified in terms of charges, sizes and electrophoretic mobilities of particles and co-ions. Dependences of enrichment factor on cross-membrane voltage, initial particle concentration and buffer ion concentrations are analyzed and the underlying reasons are elaborated. Finally, post priori a condition for validity of decoupled simulation model is given based on charges carried by focused charge particles and that by buffer co-ions. These results provide important guidance in the design and optimization of nanofluidic preconcentration and other related devices.Comment: 18 pages, 11 firgure
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