24 research outputs found
Summer seasonal amplitude of pulmonary TB cases in Wuhan, 2004–2013.
<p>Abbreviation:SE,standard error;CI,confidence interval.</p>§<p>Two-tailed two dependent samples Student's <i>t</i>-test for difference in seasonal amplitudes.</p>¶<p>Kruskal-Wallis test for all pairwise multiple comparison among seasonal amplitudes.</p><p>Summer seasonal amplitude of pulmonary TB cases in Wuhan, 2004–2013.</p
Pulmonary TB cases in Wuhan, 2004–2013.
<p>Pulmonary TB cases in Wuhan, 2004–2013.</p
Spring seasonal amplitude of pulmonary TB cases in Wuhan, 2004–2013.
<p>Abbreviation:SE,standard error; CI,confidence interval.</p>§<p>Two-tailed two dependent samples Student's <i>t</i>-test for difference in seasonal amplitudes.</p>¶<p>Kruskal-Wallis test for all pairwise multiple comparison among seasonal amplitudes.</p><p>Spring seasonal amplitude of pulmonary TB cases in Wuhan, 2004–2013.</p
The original time series of pulmonary TB cases.
<p>The original time series of pulmonary TB cases.</p
Synthesis of C<sub>60</sub>(O)<sub>3</sub>: An Open-Cage Fullerene with a Ketolactone Moiety on the Orifice
Four isomers are currently known for the trioxygenated
fullerene
derivative C<sub>60</sub>(O)<sub>3</sub>, three regioisomers with
all of the oxygen addends as epoxy groups and the unstable ozonide
isomer with a 1,2,3-trioxlane ring. Here we report the synthesis of
an open-cage isomer for C<sub>60</sub>(O)<sub>3</sub> with a ketolactone
moiety embedded into the fullerene skeleton through a three-step procedure
mediated by fullerene peroxide chemistry. Two fullerene skeleton carbon–carbon
bonds are cleaved in the process. The open-cage derivative C<sub>60</sub>(O)<sub>3</sub> can be converted back to C<sub>60</sub> through deoxygenation
with PPh<sub>3</sub>. Single crystal X-ray structure confirmed the
open-cage structure
Curculio incanus
Four isomers are currently known for the trioxygenated
fullerene
derivative C<sub>60</sub>(O)<sub>3</sub>, three regioisomers with
all of the oxygen addends as epoxy groups and the unstable ozonide
isomer with a 1,2,3-trioxlane ring. Here we report the synthesis of
an open-cage isomer for C<sub>60</sub>(O)<sub>3</sub> with a ketolactone
moiety embedded into the fullerene skeleton through a three-step procedure
mediated by fullerene peroxide chemistry. Two fullerene skeleton carbon–carbon
bonds are cleaved in the process. The open-cage derivative C<sub>60</sub>(O)<sub>3</sub> can be converted back to C<sub>60</sub> through deoxygenation
with PPh<sub>3</sub>. Single crystal X-ray structure confirmed the
open-cage structure
Global Transcriptomic Analysis of the Response of <i>Corynebacterium glutamicum</i> to Vanillin
<div><p>Lignocellulosic biomass is an abundant and renewable resource for biofuels and bio-based chemicals. Vanillin is one of the major phenolic inhibitors in biomass production using lignocellulose. To assess the response of <i>Corynebacterium glutamicum</i> to vanillin stress, we performed a global transcriptional response analysis. The transcriptional data showed that the vanillin stress not only affected the genes involved in degradation of vanillin, but also differentially regulated several genes related to the stress response, ribosome/translation, protein secretion, and the cell envelope. Moreover, deletion of the <i>sigH</i> or <i>msrA</i> gene in <i>C</i>. <i>glutamicum</i> resulted in a decrease in cell viability under vanillin stress. These insights will promote further engineering of model industrial strains, with enhanced tolerance or degradation ability to vanillin to enable suitable production of biofuels and bio-based chemicals from lignocellulosic biomass.</p></div
Response of <i>C</i>. <i>glutamicum</i> to vanillin.
<p>Schematic diagram of the genes involved in the response of <i>C</i>. <i>glutamicum</i> to vanillin stress.</p