Fibre-meshed Textile Electromagnetic Structures

This thesis investigated novel textile electromagnetic structures fabricated by a commercial computerized knitting machine. Different electronics such as elliptical waveguides, slotted waveguide antennas (SWA) and frequency selective surfaces (FSS) working at microwave band had been realized with fully textile materials. Knitted polyester was used as a dielectric and silver embedded yarn was knitted to create conducting patterns. Most of the textile electromagnetic structures in this thesis were the first time proposed to the public. Their performances were studied in both simulation and measurement

Metabolite profiles of ginsenosides Rk1 and Rg5 in zebrafish using ultraperformance liquid chromatography/quadrupole–time-of-flight MS

AbstractBackgroundIn the present study, metabolite profiles of ginsenosides Rk1 and Rg5 from red ginseng or red notoginseng in zebrafish were qualitatively analyzed with ultraperformance liquid chromatography/quadrupole–time-of-flight MS, and the possible metabolic were pathways proposed.MethodsAfter exposing to zebrafish for 24 h, we determined the metabolites of ginsenosides Rk1 and Rg5. The chromatography was accomplished on UPLC BEH C18 column using a binary gradient elution of 0.1% formic acetonitrile–0.1% formic acid water. The quasimolecular ions of compounds were analyzed in the negative mode. With reference to quasimolecular ions and MS2 spectra, by comparing with reference standards and matching the empirical molecular formula with that of known published compounds, and then the potential structures of metabolites of ginsenosides Rk1 and Rg5 were acquired.ResultsFour and seven metabolites of ginsenoside Rk1 and ginsenoside Rg5, respectively, were identified in zebrafish. The mechanisms involved were further deduced to be desugarization, glucuronidation, sulfation, and dehydroxymethylation pathways. Dehydroxylation and loss of C-17 residue were also metabolic pathways of ginsenoside Rg5 in zebrafish.ConclusionLoss of glucose at position C-3 and glucuronidation at position C-12 in zebrafish were regarded as the primary physiological processes of ginsenosides Rk1 and Rg5

The Attenuation of Moutan Cortex on Oxidative Stress for Renal Injury in AGEs-Induced Mesangial Cell Dysfunction and Streptozotocin-Induced Diabetic Nephropathy Rats

Oxidative stress (OS) has been regarded as one of the major pathogeneses of diabetic nephropathy (DN) through damaging kidney which is associated with renal cells dysfunction. The aim of this study was to investigate whether Moutan Cortex (MC) could protect kidney function against oxidative stress in vitro or in vivo. The compounds in MC extract were analyzed by HPLC-ESI-MS. High-glucose-fat diet and STZ (30 mg kg−1) were used to induce DN rats model, while 200 μg mL−1 AGEs were for HBZY-1 mesangial cell damage. The treatment with MC could significantly increase the activity of SOD, glutathione peroxidase (GSH-PX), and catalase (CAT). However, lipid peroxidation malondialdehyde (MDA) was reduced markedly in vitro or in vivo. Furthermore, MC decreased markedly the levels of blood glucose, serum creatinine, and urine protein in DN rats. Immunohistochemical assay showed that MC downregulated significantly transforming growth factor beta 2 (TGF-β2) protein expression in renal tissue. Our data provided evidence to support this fact that MC attenuated OS in AGEs-induced mesangial cell dysfunction and also in high-glucose-fat diet and STZ-induced DN rats

Magnetic phase transitions in the triangular-lattice spin-1 dimer compound K2Ni2(SeO3)3

In our study, we conduct magnetization and heat capacity measurements to investigate field-induced magnetic phase transitions within the newly synthesized compound K2Ni2(SeO3)3, a spin-1 dimer system arranged on a triangular lattice. The Ni-Ni dimers exhibit a ferromagnetic intra-dimer interaction, effectively behaving as an ensemble with a total spin of S=2. In contrast, antiferromagnetic interactions manifest between these dimers on the triangular lattice. The trigonal distortion of the NiO6 octahedra introduces easy-axis magnetic anisotropy, accounting for the distinct magnetic phase diagrams observed when applying c-axis directional and in-plnae magnetic fields. Notably, our investigation unveils a two-step phase transition with the magnetic field aligned with the c direction. We propose that the system at the first transition is from a paramagnetic state to an up-up-down state, characterized by the Z3 lattice-symmetry breaking. Subsequently, a Berezinskii-Kosterlitz-Thouless transition, involving the breaking of the c-axis spin-rotation symmetry, leads to the formation of the "Y state" at low temperatures. These findings yield valuable insights into the magnetic phase transitions inherent to geometrically frustrated magnetic systems featuring dimer structures.Comment: 10 pages, 11 figure

Characteristics of Cancer Epidemiology among 0-14 years old Chinese Children，2005—2015

BackgroundCancer has become a leading cause of death for Chinese children, imposing a great economic burden on society and families. Therefore, it is extremely important to understand the epidemicsizes and trends of childhood malignancies.ObjectiveTo analyze the epidemiological characteristics of childhood cancer in China from 2005 to 2015, so as to provide evidence for the formulation of prevention and control strategies and rational allocation of health resources concerning childhood cancer in China.MethodsData regarding cancer incidence and mortality in Chinese 0-14 years old children during 2008 to 2018 were collected from the Chinese Cancer Registry Annual Report. Age-standardized incidence and mortality rates were computed by dividing the number of child deaths caused by cancer by the fifth national population census (2010) and multiplying by 100 000. Joinpoint Regression Program was used to compute the annual percentage change (APC) to analyze the temporal trends of annual child cancer incidence and mortality rates.Results(1) During the period of 2005 to 2015, the median crude incidence rate and median crude mortality rate of cancer in 0-14 years old were 9.35/100 000, and 3.91/100 000, respectively. The median crude incidence and median crude mortality rate of 0-4 years old group were higher than those of 5-9 years old group and 10-14 years old group (P<0.05) . (2) The median crude incidence rate (10.21/100 000 vs 8.91/100 000) and median crude mortality rate (4.18/100 000 vs 3.47/100 000) of cancer in male children aged 0-14 years old were higher than those of female children of the same age (P<0.05) . (3) The median crude incidence rate (10.87/100 000 vs 7.20/100 000) and median crude mortalityrate (4.08/100 000 vs 3.54 /100 000) of cancer in urban children aged 0-14 years old were higher than those of rural children of the same age (P<0.05) . (4) The median crude mortality rate of cancer showed an upward trend in 0-14 years old in the period of 2005 to 2015 (APC=1.01%, P<0.05) ; amomg them, the median crude mortality rate in the 0-4 years old group showed an decreased trend (APC=-1.19%, P<0.05) ; the median crude mortality rate in the 5-9 years old group showed an increased trend (APC=2.50%, P<0.05) ; the median crude mortality rate in the 10-14 years old group was stable over time. (5) The median crude incidence rate and median crude mortality rate of cancer in rural 0-14 years old in rural areas presented an upward trend over the period 2005 to 2015 (APC=7.73%, 2.22%, P<0.05) . (6) The top six cancers among children aged 0-14 years old in this period were: leukemia, brain cancer, lymphoma, bone cancer, kidney cancer and liver cancer.ConclusionThe cancer incidence and mortality rate in Chinese 0-14 years old children showed different features by time, age group or geographical region (rural or urban) . Priorities for containing cancer should be given to rural children, 5-9 years old children or children with brain cancer or leukemia