N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine

The title compound, C19H21NOS, is an inter­mediate for the synthesis of duloxetine hydro­chloride. In the mol­ecular structure, the thio­phene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms are as expected. In the crystal structure, no classical hydrogen bonds are found

Solving a class of matrix minimization problems by linear variational inequality approaches

AbstractA class of matrix optimization problems can be formulated as a linear variational inequalities with special structures. For solving such problems, the projection and contraction method (PC method) is extended to variational inequalities with matrix variables. Then the main costly computational load in PC method is to make a projection onto the semi-definite cone. Exploiting the special structures of the relevant variational inequalities, the Levenberg–Marquardt type projection and contraction method is advantageous. Preliminary numerical tests up to 1000×1000 matrices indicate that the suggested approach is promising

2-[1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yloxycarbonyl]benzoic acid

The asymmetric unit of the title compound, C15H14ClN3O6, contains two independent mol­ecules. The imidazole rings are oriented with respect to the benzene rings at dihedral angles of 19.66 (3) and 21.64 (3)°. In the crystal structure, inter­molecular O—H⋯N hydrogen bonds link the mol­ecules into infinite chains

Complete genome sequence and architecture of crucian carp Carassius auratus herpesvirus (CaHV)

Crucian carp Carassius auratus herpesvirus (CaHV) was isolated from diseased crucian carp with acute gill hemorrhages and high mortality. The CaHV genome was sequenced and analyzed. The data showed that it consists of 275,348 bp and contains 150 predicted ORFs. The architecture of the CaHV genome differs from those of four cyprinid herpesviruses (CyHV1, CyHV2, SY-C1, CyHV3), with insertions, deletions and the absence of a terminal direct repeat. Phylogenetic analysis of the DNA polymerase sequences of 17 strains of Herpesvirales members, and the concatenated 12 core ORFs from 10 strains of alloherpesviruses showed that CaHV clustered together with members of the genus Cyprinivirus, family Alloherpesviridae.</p