4,659 research outputs found

    Research on Cascading Use of Waste Heat Technical Program in Heavy Oil Exploitation by SAGD Technology

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    AbstractIn Du 84 block Shu 1 area in Liaohe oilfield where used SAGD technology to exploit heavy oil, the temperature of wellhead produced fluid can reach up to 170-180°C, In view of this problem of wasting large amount of thermal energy, this paper proposes a set of technical program of cascading use of waste heat with the combination of generation of electrical energy and heating. Meanwhile, the generating capacity and heating area of the program as well as its economic efficiency are also calculated and analyzed. In addition, the parameters of generating system's condenser are optimized by taking the annual total cost of the condenser as the objective function and using majorized function fminsearch in MATLAB software, and the most superior technical parameters are determined. The result can offer some reference in using of waste heat in practical project

    Effects of Pharmacological Block of GABAA Receptors on Pallidal Neurons in Normal and Parkinsonian State

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    The globus pallidus plays a central integrative role in the basal ganglia circuitry. Morphological studies have revealed a high level of GABA and GABAA receptors in the globus pallidus. To further investigate the effects of endogenous GABAA neurotransmission in the globus pallidus of normal and parkinsonian rats, in vivo extracellular recording and behavioral tests were performed in the present studies. In normal rats, micro-pressure ejection of GABAA receptor antagonist gabazine (0.1 mM) increased the spontaneous firing rate of pallidal neurons by 28.3%. Furthermore, in 6-hydroxydopamine parkinsonian rats, gabazine increased the firing rate by 46.0% on the lesioned side, which was significantly greater than that on the unlesioned side (21.5%, P < 0.05), as well as that in normal rats (P < 0.05). In the behaving rats, unilateral microinjection of gabazine (0.1 mM) evoked consistent contralateral rotation in normal rats, and significantly potentiated the number of apomorphine-induced contralateral rotations in parkinsonian rats. The present electrophysiological and behavioral findings may provide a rational for further investigations into the potential of pallidal endogenous GABAA neurotransmission in the treatment of Parkinson's disease
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