Shadows and photon spheres with spherical accretions in the four-dimensional Gauss-Bonnet black hole

We investigate the shadows and photon spheres of the four-dimensional Gauss-Bonnet black hole with the static and infalling spherical accretions. We show that for both cases, the shadow and photon sphere are always present. The radii of the shadow and photon sphere are independent of the profiles of accretion for a fixed Gauss-Bonnet constant, implying that the shadow is a signature of the spacetime geometry and it is hardly influenced by accretion in this case. Because of the Doppler effect, the shadow of the infalling accretion is found to be darker than that of the static one. We also investigate the effect of the Gauss-Bonnet constant on the shadow and photon sphere, and find that the larger the Gauss-Bonnet constant is, the smaller the radii of the shadow and photon sphere will be. In particular, the observed specific intensity increases with the increasing of the Gauss-Bonnet constant.Comment: published versio

Deltaline from Delphinium delavayi Franch

The title compound [systematic name: 6β,10-dihy­droxy-1α,14α,16β-trimeth­oxy-4-methyl-7β,8-(methyl­enedi­oxy)-20-ethyl­aconitan-6-yl acetate], C27H41NO8, is a C19-diterpenoid alkaloid and a major diterpenoid alkaloid component of the roots of Delphinium delavayi Franch. var. pogonanthum (Hand.-Mazz.) W. T. Wang. The mol­ecule has a lycoctonine carbon-atom skeleton with four six-membered rings and three five-membered rings among; three of the six-membered rings adopt chair conformations with the fourth adopting a boat conformation while all of the five-membered rings exhibit envelope conformations. Inter­molecular O—H⋯O hydrogen bonding is present in the crystal structure

Anti-endometriotic effect of Angelica sinensis (Oliv.) Diels extract in human endometriotic cells and rats

Purpose: To study the anti-endometriotic effect of Angelica sinensis (Oliv.) Diels extract (ASDE) in human endometriotic cells and rats.Method: Forty female rats were randomly divided into four groups (10 rats/group): control, endometriosis+danazol, endometriosis+high dose of ASDE and low dose of ASDE. The rats were orally administered either vehicle (200 μL of PBS) alone or ASDE (140, 280 and 560 mg/kg/day) for 5 weeks. Danazol was used as the control drug. After induction of endometriosis for 4 weeks, the rats were sacrificed by cervical dislocation and the peritoneum and visceral organs examined visually to measure the number of endometriotic lesions. Serum levels of cancer antigen 125 (CA-125) and interleukin 13 (IL-13), interleukin 18 (IL-18) and tumor necrosis factor-alpha (TNF-α) of peritoneal fluids of rats were measured using ELISA kits. Western blot assay was performed to measure the levels of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9)  expressions after 24 h of treatment with ASDE (30, 60, and 120 μg/mL).Results: ASDE-treated rats displayed reduced numbers of total endometriotic lesions when compared with vehicle-treated controls (p < 0.01). When the rats were treated with high dose of ASDE, serum CA-125 level, as well as IL-18 and TNF-α levels in peritoneal fluids were significantly lower than that of the control group (p < 0.01); however, IL-13 level in peritoneal fluids was significantly higher than that of the control group (p < 0.01). ASDE treatment significantly suppressed the levels of MMP-2 and MMP-9 protein in 11Z cell (p < 0.01).Conclusion: The results reveal that ASDE exhibits significant anti-endometriotic effect by inhibiting inflammatory factors in rats. Thus, the plant extract can potentially be developed for the clinical management of endometriosis. Keywords: Angelica sinensis, Endometriosis, Cancer antigen, Endometriotic lesions, Matrix metalloproteinas

Parallel compressive super-resolution imaging with wide field-of-view based on physics enhanced network

Achieving both high-performance and wide field-of-view (FOV) super-resolution imaging has been attracting increasing attention in recent years. However, such goal suffers from long reconstruction time and huge storage space. Parallel compressive imaging (PCI) provides an efficient solution, but the super-resolution quality and imaging speed are strongly dependent on precise optical transfer function (OTF), modulation masks and reconstruction algorithm. In this work, we propose a wide FOV parallel compressive super-resolution imaging approach based on physics enhanced network. By training the network with the prior OTF of an arbitrary 128x128-pixel region and fine-tuning the network with other OTFs within rest regions of FOV, we realize both mask optimization and super-resolution imaging with up to 1020x1500 wide FOV. Numerical simulations and practical experiments demonstrate the effectiveness and superiority of the proposed approach. We achieve high-quality reconstruction with 4x4 times super-resolution enhancement using only three designed masks to reach real-time imaging speed. The proposed approach promotes the technology of rapid imaging for super-resolution and wide FOV, ranging from infrared to Terahertz

Order Picking Optimization in Carousels Storage System

This paper addresses the order picking problem in a material handling system consisting of multiple carousels and one picker. Carousels are rotatable closed-loop storage systems for small items, where items are stored in bins along the loop. An order at carousels consists of n different items stored there. The objective is to find an optimal picking sequence to minimizing the total order picking time. After proving the problem to be strongly NP-hard and deriving two characteristics, we develop a dynamic programming algorithm (DPA) for a special case (two-carousel storage system) and an improved nearest items heuristics (INIH) for the general problem. Experimental results verify that the solutions are quickly and steadily achieved and show their better performance