Chaos-assisted two-octave-spanning microcombs

Since its invention, optical frequency comb has revolutionized a broad range of subjects from metrology to spectroscopy. The recent development of microresonator-based frequency combs (microcombs) provides a unique pathway to create frequency comb systems on a chip. Indeed, microcomb-based spectroscopy, ranging, optical synthesizer, telecommunications and astronomical calibrations have been reported recently. Critical to many of the integrated comb systems is the broad coverage of comb spectra. Here, microcombs of more than two-octave span (450 nm to 2,008 nm) is demonstrated through χ^((2)) and χ^((3)) nonlinearities in a deformed silica microcavity. The deformation lifts the circular symmetry and creates chaotic tunneling channels that enable broadband collection of intracavity emission with a single waveguide. Our demonstration introduces a new degree of freedom, cavity deformation, to the microcomb studies, and our microcomb spectral range is useful for applications in optical clock, astronomical calibration and biological imaging

An AMC Backed Folded Dipole Slot Antenna Based on CMOS Process

A fold dipole slot antenna backed by artificial magnetic conductor (AMC) structure based on a standard 0.18 um CMOS process on chip application is firstly proposed in this paper. Conventional silicon antenna on chip (AoC) suffers from low radiation performance because the most electromagnetic energy is restricted in silicon substrate as surface wave for its high dielectric permittivity. The energy is dissipated as thermal for low resistivity of silicon substrate. AMC constructed by a periodic 6*6 square patch array is adopted as background to improve radiation performance of the proposed folded dipole slot AoC. Gain of the proposed AMC backed AoC is improved about 3.5 dB compared with that of the same AoC without AMC background

Anti-endometriotic effect of Angelica sinensis (Oliv.) Diels extract in human endometriotic cells and rats

Purpose: To study the anti-endometriotic effect of Angelica sinensis (Oliv.) Diels extract (ASDE) in human endometriotic cells and rats.Method: Forty female rats were randomly divided into four groups (10 rats/group): control, endometriosis+danazol, endometriosis+high dose of ASDE and low dose of ASDE. The rats were orally administered either vehicle (200 μL of PBS) alone or ASDE (140, 280 and 560 mg/kg/day) for 5 weeks. Danazol was used as the control drug. After induction of endometriosis for 4 weeks, the rats were sacrificed by cervical dislocation and the peritoneum and visceral organs examined visually to measure the number of endometriotic lesions. Serum levels of cancer antigen 125 (CA-125) and interleukin 13 (IL-13), interleukin 18 (IL-18) and tumor necrosis factor-alpha (TNF-α) of peritoneal fluids of rats were measured using ELISA kits. Western blot assay was performed to measure the levels of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9)  expressions after 24 h of treatment with ASDE (30, 60, and 120 μg/mL).Results: ASDE-treated rats displayed reduced numbers of total endometriotic lesions when compared with vehicle-treated controls (p < 0.01). When the rats were treated with high dose of ASDE, serum CA-125 level, as well as IL-18 and TNF-α levels in peritoneal fluids were significantly lower than that of the control group (p < 0.01); however, IL-13 level in peritoneal fluids was significantly higher than that of the control group (p < 0.01). ASDE treatment significantly suppressed the levels of MMP-2 and MMP-9 protein in 11Z cell (p < 0.01).Conclusion: The results reveal that ASDE exhibits significant anti-endometriotic effect by inhibiting inflammatory factors in rats. Thus, the plant extract can potentially be developed for the clinical management of endometriosis. Keywords: Angelica sinensis, Endometriosis, Cancer antigen, Endometriotic lesions, Matrix metalloproteinas

[3-Bromo­meth­yl-1-(4-methyl­phenyl­sulfon­yl)azetidin-3-yl]methanol

The asymmetric unit of the title compound, C12H16BrNO3S, contains two independent mol­ecules. In each mol­ecule, the azetidine four-membered ring adopts a nearly planar conformation, the maximum deviations being 0.087 (3) and 0.079 (3) Å. The mean azetidine plane is twisted by 75.2 (2) and 73.6 (2)° with respect to the plane of the benzene ring in the two independent mol­ecules. The crystal packing is stabilized by O—H⋯O hydrogen bonds

Complete two-loop electroweak corrections to e+e−→HZe^+e^-\rightarrow HZ

We compute the complete two-loop electroweak corrections to the Higgsstralung process $e^+e^-\rightarrow HZ$ at the future Higgs factory. The Feynman integrals involved in the computation are decomposed into linear combinations of a minimal set of master integrals taking advantage of the recent developments of integral reduction techniques. The master integrals are then evaluated by differential equations with boundary conditions provided by the auxiliary mass flow method. Our final result for given $\sqrt{s}$ is expressed as a piecewise function defined by several deeply expanded power series, which has high precision and can be further manipulated efficiently. Our calculation presents the first complete two-loop electroweak corrections for processes with four external particles.Comment: 5 pages, 2 figures. arXiv admin note: text overlap with arXiv:2209.1425

Flavonoids with α-glucosidase inhibitory activities and their contents in the leaves of Morus atropurpurea

BACKGROUND: This study aims to isolate the α-glucosidase inhibitory compounds from mulberry leaves (Morus atropurpurea Roxb., Moraceae) and to develop an analytical method for quantification of the compounds. METHODS: Four flavonoids, rutin (1), isoquercetin (2), kaempferol-3-O-rutinoside (3) and astragalin (4), were isolated by column chromatography from mulberry leaf water extracts (MWE). The α-glucosidase inhibitory activities of MWE and the four isolated compounds were evaluated by a microplate-based in vitro assay. The content of the isolated flavonoids in M. atropurpurea leaves purchased from different local herbal stores or collected in different locations was determined by high performance liquid chromatography. RESULTS: The four flavonoids (1–4) showed α-glucosidase inhibitory activities, with rutin (1) and astragalin (4) showing high α-glucosidase inhibitory activities (IC(50) values of 13.19 ± 1.10 and 15.82 ± 1.11 μM, respectively). The total contents of the four flavonoids were different among eight samples examined, ranging from 4.34 mg/g to 0.53 mg/g. CONCLUSIONS: The four flavonoids in M. atropurpurea leaves could inhibit α-glucosidase activity