1,104 research outputs found

    We have emotions but can’t show them! Authoritarian leadership, emotion suppression climate, and team performance

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    How do authoritarian leaders in modern organizations influence work team emotional climate and performance? Defining authoritarian leadership as an ambient, demanding, and controlling leadership style, we conducted a survey study of 252 leaders and 765 subordinates matched in 227 work teams in three large public Japanese organizations. The results indicate that authoritarian leaders are more likely to create a team climate of emotion suppression, which induces a higher level of team emotional exhaustion that negatively impacts team performance. Furthermore, we found that authoritarian leaders’ own emotion suppression enhances the above sequential mediation effects, i.e. the more emotion suppression the authoritarian leader him/herself exercises, the stronger the team climate of emotion suppression, the higher the level of team emotional exhaustion, and the lower the team performance. These findings suggest that leadership effectiveness may be improved if leaders can reduce their authoritarian behaviors and identify appropriate channels for employees to release emotions in the workplace

    Identification of key genes in late-onset major depressive disorder through a co-expression network module

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    Late-onset major depressive disorder (LOD) increases the risk of disability and suicide in elderly patients. However, the complex pathological mechanism of LOD still remains unclear. We selected 10 LOD patients and 12 healthy control samples from the GSE76826 dataset for statistical analysis. Under the screening criteria, 811 differentially expressed genes (DEGs) were screened. We obtained a total of two most clinically significant modules through the weighted gene co-expression network analysis (WGCNA). Functional analysis of the genes in the most clinically significant modules was performed to explore the potential mechanism of LOD, followed by protein–protein interaction (PPI) analysis and hub gene identification in the core area of the PPI network. Furthermore, we identified immune infiltrating cells using the cell-type identification by estimating relative subsets of RNA transcripts (CIBERSORT) algorithm between healthy subjects and LOD patients with the GSE98793 dataset. Next, six hub genes (CD27, IL7R, CXCL1, CCR7, IGLL5, and CD79A) were obtained by intersecting hub genes with DEGs, followed by verifying the diagnostic accuracy with the receiver operating characteristic curve (ROC). In addition, we constructed the least absolute shrinkage and selection operator (LASSO) regression model for hub gene cross-validation. Finally, we found that CD27 and IGLL5 were good diagnostic indicators of LOD, and CD27 may be the key gene of immune function change in LOD. In conclusion, our research shows that the changes in the immune function may be an important mechanism in the development of LOD, which can provide some guidance for the related research of LOD in the future

    DAA: A Delta Age AdaIN operation for age estimation via binary code transformer

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    Naked eye recognition of age is usually based on comparison with the age of others. However, this idea is ignored by computer tasks because it is difficult to obtain representative contrast images of each age. Inspired by the transfer learning, we designed the Delta Age AdaIN (DAA) operation to obtain the feature difference with each age, which obtains the style map of each age through the learned values representing the mean and standard deviation. We let the input of transfer learning as the binary code of age natural number to obtain continuous age feature information. The learned two groups of values in Binary code mapping are corresponding to the mean and standard deviation of the comparison ages. In summary, our method consists of four parts: FaceEncoder, DAA operation, Binary code mapping, and AgeDecoder modules. After getting the delta age via AgeDecoder, we take the average value of all comparison ages and delta ages as the predicted age. Compared with state-of-the-art methods, our method achieves better performance with fewer parameters on multiple facial age datasets.Comment: Accepted by CVPR2023; 8 pages, 3 figure

    The environments of Type Ia supernovae with different relative equivalent width of Si II feature in their spectra

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    Although type Ia supernovae are so important in many astrophysical field, e.g. in cosmology, their explosion mechanism and progenitor system are still unclear. In physics, the relative equivalent width (REW) of the Si II 635.5 nm absorption feature reflects the velocity interval of silicon in the supernova ejecta and then may provide constraints on the explosion mechanism of SNe Ia. In this paper, we divide the SNe Ia into broad line (BL) and normal line (NL) subsamples based on their REW of Si II 635.5 nm absorption lines around maximum light, and find that the BL SNe Ia have a dimmer mean brightness than NL ones, which possibly results from their different metallicities. However, based on the pixel statistics study on the environments of two subsamples, we do not find any significant potential difference on the environments between BL and NL SNe Ia, which implies that the explosion mechanism of SNe Ia could be independent of their progenitor populations.Comment: 17 pages, 13 figures, accepted for publication in Ap

    Effects of age, sex and pathological type on the risk of multiple polyps: A Chinese teaching hospital study

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/162741/2/cdd12863.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/162741/1/cdd12863_am.pd

    Oxygen uptake rate (OUR) control strategy for improving avermectin B1a production during fed-batch fermentation on industrial scale (150 m3)

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    Glucose metabolism plays a crucial role in the process of avermectin B1a biosynthesis. Controlling glucose feeding based on oxygen uptake rate (OUR) was established to improve the efficiency of avermectin B1a  production. The result showed that avermectin B1a production was greatly enhanced by OUR control strategy. In the glucose feeding phase, OUR was maintained at approximate 12 mmol/L/h, which was conducive to avermectin B1a biosynthesis. Using this OUR control strategy, an adequate supply of organic acid precursors produced avermectin B1a 5228 U/mL, which was 22.8% higher than that of the control (batch fermentation, 4256 U/mL) on industrial scale.Key words: Avermectin B1a, glucose feeding, oxygen uptake rate, industrial scale

    AU-Rich Long 3′ Untranslated Region Regulates Gene Expression in Bacteria

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    3′ untranslated regions (3′ UTRs) and particularly long 3′ UTRs have been shown to act as a new class of post-transcriptional regulatory element. We previously reported that hmsT mRNA stability is negatively regulated by the 3′ UTR of hmsT in Yersinia pestis. To investigate more general effects of 3′ UTRs in Y. pestis, we selected 15 genes potentially possessing long 3′ UTRs with different AU content and constructed their 3′ UTR deletion mutants. Deletion of AU-rich 3′ UTRs increased mRNA levels, whereas deletion of 3′ UTRs with normal AU content resulted in slight or no changes in the mRNA level. In addition, we found that PNPase was important for 3′ UTR-mediated mRNA decay when the transcriptional terminator was Rho-dependent. Finally, we showed that ribosomes promote mRNA stability when bound to a 3′ UTR. Our findings suggest that functional 3′ UTRs might be broadly distributed in bacteria and their novel regulatory mechanisms require further investigation
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