Theoretical Study of Infrared Spectra of OCS‑(<i>p</i>H₂)₂, OCS‑(<i>o</i>D₂)₂, OCS-(HD)₂, and Mixed OCS‑<i>p</i>H₂‑He Trimers

The calculated rovibrational energy levels and infrared spectra for OCS-(<i>p</i>H₂)₂, OCS-(<i>o</i>D₂)₂, OCS-(HD)₂ and mixed OCS-<i>p</i>H₂-He trimers are obtained by performing the exact basis-set calculations for the first time based on the newly developed potential energy surfaces (<i>J. Chem. Phys.</i> <b>2017</b>, 147, 044313). The “adiabatic-hindered-rotor” (AHR) method is used for reduced-dimension treatment of the hydrogen rotation. The predicted band origin shifts and the infrared spectra are in good agreement with the available experimental values: for the band origin shifts and infrared transitions, the root-mean-square­(rms) deviations are smaller than 0.044 and 0.002 cm^–1, respectively. We extend the assignments to the unrecorded infrared transitions for OCS-(<i>p</i>H₂)₂ and OCS-(HD)₂ complexes and identify the infrared spectra for OCS-(<i>o</i>D₂)₂ and OCS-<i>p</i>H₂-He for the first time. Three-dimensional density distributions for the ground states of OCS-(<i>p</i>H₂)₂, OCS-<i>p</i>H₂-He, and OCS-(He)₂ show that the <i>p</i>H₂ molecules are localized in their corresponding global minimum regions, while the pronounced locations of the He atoms are missing in OCS-<i>p</i>H₂-He and OCS-(He)₂ with forming incomplete circles around the OCS axis. A clear tunneling splitting is observed for the torsional motion of the two hydrogen molecules (<i>p</i>H₂, HD, or <i>o</i>D₂) on a ring about the OCS molecular axis, whereas no tunneling splitting is found in OCS-<i>p</i>H₂-He or OCS-(He)₂ due to a much lower torsional barrier

A new isoflavanone from <i>Ficus tikoua</i> Bur

<p>A new isoflavanone compound, ficustikounone A (<b>1</b>), together with 22 known flavones, was isolated from <i>Ficus tikoua</i> Bur. The structures of these isolates were determined by UV, ECD, HRESIMS, 1D and 2D spectral analyses.</p

Cytotoxic Phorbol Esters of <i>Croton tiglium</i>

Chemical investigation of the seeds of <i>Croton tiglium</i> afforded eight new phorbol diesters (three phorbol diesters, <b>1</b>–<b>3</b>, and five 4-deoxy-4α-phorbol diesters, <b>4</b>–<b>8</b>), together with 11 known phorbol diesters (nine phorbol diesters, <b>9</b>–<b>17</b>, and two 4-deoxy-4α-phorbol diesters, <b>18</b> and <b>19</b>). The structures of compounds <b>1</b>–<b>8</b> were determined by spectroscopic data information and chemical degradation experiments. The cytotoxic activities of the phorbol diesters were evaluated against the SNU387 hepatic tumor cell line, and compound <b>3</b> exhibited the most potent activity (IC₅₀ 1.2 μM)

Turn-On Fluorescence Sensor for Intracellular Imaging of Glutathione Using g‑C₃N₄ Nanosheet–MnO₂ Sandwich Nanocomposite

Herein, a novel fluorescence sensor based on g-C₃N₄ nanosheet–MnO₂ sandwich nanocomposite has been developed for rapid and selective sensing of glutathione (GSH) in aqueous solutions, as well as living cells. The graphitic-phase C₃N₄ (g-C₃N₄) nanosheet used here is a new type of carbon-based nanomaterial with high fluorescence quantum yield and high specific surface area. We demonstrate a facile one-step approach for the synthesis of a g-C₃N₄ nanosheet–MnO₂ sandwich nanocomposite for the first time. The fluorescence of g-C₃N₄ nanosheet in this nanocomposite is quenched, which attributing to fluorescence resonance energy transfer (FRET) from a g-C₃N₄ nanosheet to the deposited MnO₂. Upon the addition of GSH, MnO₂ is reduced to Mn²⁺, which leads to the elimination of FRET. As a result, the fluorescence of g-C₃N₄ nanosheet is restored. Importantly, the chemical response of the g-C₃N₄–MnO₂ nanocomposite exhibits great selectivity toward GSH relative to other electrolytes and biomolecules. Under the optimal conditions, the detection limit of 0.2 μM for GSH in aqueous solutions can be reached. Furthermore, the g-C₃N₄–MnO₂ nanocomposite is confirmed to be membrane-permeable and have low cytotoxicity. Moreover, we successfully apply this sensor for visualizing and monitoring change of the intracellular GSH in living cells. Moreover, the proposed sensor shows satisfying performance, such as low cost, easy preparation, rapid detection, good biocompatibility, and turn-on fluorescence response

Mn-Incorporation-Induced Phase Transition in Bottom-Up Synthesized Colloidal Sub-1-nm Ni(OH)₂ Nanosheets for Enhanced Oxygen Evolution Catalysis

Sub-1-nm structures are attractive for diverse applications owing to their unique properties compared to those of conventional nanomaterials. Transition-metal hydroxides are promising catalysts for oxygen evolution reaction (OER), yet there remains difficulty in directly fabricating these materials within the sub-1-nm regime, and the realization of their composition and phase tuning is even more challenging. Here we define a binary-soft-template-mediated colloidal synthesis of phase-selective Ni(OH)2 ultrathin nanosheets (UNSs) with 0.9 nm thickness induced by Mn incorporation. The synergistic interplay between binary components of the soft template is crucial to their formation. The unsaturated coordination environment and favorable electronic structures of these UNSs, together with in situ phase transition and active site evolution confined by the ultrathin framework, enable efficient and robust OER electrocatalysis. They exhibit a low overpotential of 309 mV at 100 mA cm–2 as well as remarkable long-term stability, representing one of the most high-performance noble-metal-free catalysts

Subgroup analyses of outcome VA gain 20/40 in high and low concentration of ICG versus non-ICG group.

<p>There were no differences between the high or low concentration of ICG group and the non-ICG group.</p

Subgroup analyses of outcome VA gain 20/40 in high and low concentration of ICG versus non-ICG group.

<p>The rate of VA gain ≥20/40 was lower in high concentration ICG group compared with non-ICG group, while no difference was observed between low concentration ICG and non-ICG group.</p

Characteristics of Eligible Studies.

<p>RR: relative risk; OR: odds ratios; CI: confidence interval; AMD: age-related macular degeneration.</p

Forest plot for VA gain ≥20/40 in different follow up duration.

<p>The rate of VA gain ≥20/40 was lower in ICG group compared with the non-ICG group, while no difference was observed in longer follow-up duration.</p

Description of the characteristics of the included trials.

<p>— = no data provided; RCT = randomized-controlled trials; LOE = level of evidence.</p>a<p>The part included in the partly retrospective study is retrospective.</p>b<p>The study quality is evaluated by Downs and Black score and Newcastle-Ottowa Scale (NOS). The Downs and Black score for both RCT and non-RCT while NOS for RCT only.</p>c<p>The matching factors are: (1) age, (2) gender, (3) macular hole type, (4) symptom duration, (5) preoperative visual acuity, (6) one surgeon, (7), follow-up time.</p