Complementary relations of entanglement, coherence, steering and Bell nonlocality inequality violation in three-qubit states

We put forward complementary relations of entanglement, coherence, steering inequality violation, and Bell nonlocality for arbitrary three-qubit states. We show that two families of genuinely entangled three-qubit pure states with single parameter exist, and they exhibit maximum coherence and steering inequality violation for a fixed amount of negativity, respectively. It is found that the negativity is exactly equal to the geometric mean of bipartite concurrences for the three-qubit pure states, although the negativity is always less than or equal to the latter for three-qubit mixed states. Moreover, the complementary relation between negativity and first-order coherence for tripartite entanglement states are established. Furthermore, we investigate the close relation between the negativity and the maximum steering inequality violation. In addition, the complementary relation between negativity and the maximum Bell-inequality violation for arbitrary three-qubit states is obtained. The results provide reliable evidence of fundamental connections among entanglement, coherence, steering inequality violation, and Bell nonlocality.Comment: 11 pages, 5 figure

The association of XRCC1 gene single nucleotide polymorphisms with response to neoadjuvant chemotherapy in locally advanced cervical carcinoma

<p>Abstract</p> <p>Background</p> <p>Platinum-based neoadjuvant chemotherapy (NAC) is new therapeutic strategy for locally advanced cervical carcinoma, but the variables used to predict NAC response are still infrequently reported. The aim of our study was to investigate the association between <it>XRCC1 </it>gene single nucleotide polymorphisms (SNPs) and NAC response.</p> <p>Methods</p> <p>Seventy patients with locally advanced cervical carcinoma who underwent NAC were collected. SNPs of <it>XRCC1 </it>(at codon 194 and 399) and XRCC1 protein expression were detected. The association of <it>XRCC1 </it>gene SNPs and protein expression with NAC response were analyzed.</p> <p>Results</p> <p>Response to NAC was not statistically significant in three genotypes, Arg/Arg, Arg/Trp, Trp/Trp of <it>XRCC1 </it>at codon 194(X²= 1.243, P = 0.07), while responses were significantly different in genotypes Arg/Arg, Arg/Gln, Gln/Gln of <it>XRCC1 </it>at codon 399 (X²= 2.283, P = 0.020). The risk of failure to chemotherapy in the patients with a Gln allele(Arg/Gln+Gln/Gln) was significantly greater than that with Arg/Arg(OR = 3.254, 95%CI 1.708 ~ 14.951). The expression level of XRCC1 protein was significantly associated with response to NAC. Moreover, the genotype with the Gln allele(Arg/Gln+Gln/Gln) at codon 399, but not codon at 194, presented a significantly higher level of XRCC1 protein expression than that with Arg/Arg genotype (F = 2.699, p = 0.009).</p> <p>Conclusion</p> <p>SNP of <it>XRCC1 </it>gene at codon 399 influences the response of cervical carcinoma to platinum-based NAC. This is probably due to changes in expression of XRCC1 protein, affecting response to chemotherapy.</p

Physiological and Metabolomic Alterations in Macrocystis pyrifera upon Exposure to Chromium(VI)

1593-1599In order to comprehensively characterize the effects of chromium (VI) on physiological and metabonomic performance of Macrocystis pyrifera, the sporophytes were exposed to 2 mg L-1 potassium dichromate for 3 days. M. pyrifera sporophytes showed decreased pigment content and Chla fuloresecnece parameters with the accumulation of Cr(VI). The carbon content was clearly increased, while the content of nitrogen, hydrogen and sulfur were little changed. Moreover, an untargeted metabolomic analysis was carried out in order to investigate the metabolic effects and to obtain a comprehensive profiling of induced metabolites during Cr stress. Absolute quantification of 14 different metabolites was obtained through GC-MS methods. The principal component analysis showed a clear separation between control and Cr treated samples. Some pathways including carbon fixation, sulfur metabolism, taurine and hypotaurine metabolism were affected by Cr (VI) stress. These findings provided valuable information to elucidate the mechanism of M. pyrifera upon Cr (VI) stress

Nonreciprocal entanglement in cavity-magnon optomechanics

Cavity optomechanics, a promising platform to investigate macroscopic quantum effects, has been widely used to study nonreciprocal entanglement with Sagnec effect. Here we propose an alternative way to realize nonreciprocal entanglemment among magnons, photons, and phonons in a hybrid cavity-magnon optomechanics, where magnon Kerr effect is used. We show that the Kerr effect gives rise to a magnon frequency shift and an additional two-magnon effect. Both of them can be tuned from positive to negative via tuning the magectic field direction, leading to nonreciprocity. By tuning system parameters such as magnon frequency detuning or the coefficient of the two-magnon effect, bipartite and tripartite entanglements can be nonreciprocally enhanced. By further studying the defined bidirectional contrast ratio, we find that nonreciprocity in our system can be switch on and off, and can be engineered by the bath temperature. Our proposal not only provides a potential path to demonstrate nonreciprocal entanglement with the magnon Kerr effect, but also opens a direction to engineer and design diverse nonreciprocal devices in hybrid cavity-magnon optomechanics with nonlinear effects.Comment: 8 pages,4 figures. Accepted by Phys. Rev.

Establishment and assessments of a new model for the postoperative fatigue syndrome by major small intestinal resection in rats

Objective. Postoperative fatigue syndrome (POFS) is a general and main complication after surgery. However, there is no stable and standardized animal model for POFS. The aim of the present study was to establish a rodent model of POFS by small intestinal resection, with POFS evaluated by acknowledged physical and behavioral methods. Material and Methods. Forty-two Sprague-Dawley rats were randomly divided into four groups according to the length of a "middle" small intestinal resection: 0% (sham group; i.e., laparotomy alone), 10%, 40% and 70% groups, with corresponding lengths of small intestinal resections. Following surgery, the general state of health was evaluated. Tail suspension test, open field test and Morris water maze test were used to evaluate the degree of POFS. Serum albumin, transferrin, prealbumin and fibronectin were measured to assess the nutritional status, and superoxide dismutase (SOD) and malondialdehyde (MDA) were also measured. Results. As compared with the other three groups, the 70% small intestinal resection group showed the worst general state of health, decreased strength of the tail suspension test and decreased score of Morris water maze test (p < 0.05) after operation. All rats in whom the small intestinal resection was done demonstrated a certain degree of malnutrition and behavior of depression, and the 70% resection group had the lowest levels of transferrin, prealbumin and fibronectin as compared with the other groups (p < 0.05), as well as decreased SOD and increased MDA in serum (p < 0.05). Conclusions. Resection of 70% of the small intestine resulted in typical characteristics of POFS. As this procedure is simple, stable and easily reproducible, it may serve as a model for research on POFS