Sphere masks encompassing the IPL, EBA, FBA, ACC, MPFC, DLPFC, amygdala and insula used in ROI analyses of <i>f</i>MRI data.

<p>Red, inferior partial lobe (IPL); blue, extrastriate body area (EBA); green, fusiform body area (FBA); pink, dorsal lateral prefrontal cortex (DLPFC); yellow, anterior cingulate cortex (ACC); violet, median prefrontal cortex (MPFC); cyan, amygdala; orange, insula.</p

Positive correlations between NPS-F scores and neural activations during fat vs. thin body image self-reflection in left amygdala (x = -29, y = -7, z = -20) and left DLPFC (x = -48, y = 7, z = 36).

<p>Significant p value was corrected by the Bonferroni method, that significant differences were determined if the <i>p</i> < .05/16 = 0.003.</p

Generalized Conversion of Halogen-Containing Plastic Waste into Nanoporous Carbon by a Template Carbonization Method

Halogen-containing plastic materials have been converted into nanoporous carbon by a template carbonization method, using zinc powder as an efficient hard template. The mass ratio between plastics and zinc powder as well as carbonization temperature plays a crucial role in determining the carbon structures and resultant electrochemical performances. The <b>PTFE-1:3-700</b> sample that is obtained by carbonizing polytetrafluoroethene and zinc powder (the mass ratio of 1:3) at 700 °C has a large BET surface area of 800.5 m² g^–1 and a high total pore volume of 1.59 cm³ g^–1, also delivering excellent specific capacitance of 313.7 F g^–1 at 0.5 A g^–1. Moreover, it exhibits a superior cycling stability with high capacitance retention of 93.10% after cycling for 5000 times. More importantly, it can be extended to produce nanoporous carbon derived from other halogen-containing plastic materials such as poly­(vinylidene fluoride) and poly­(vinyl chloride), revealing the generality of the synthesis method

Demographic Information and self-reported data of Participants: Mean (Standard Deviation).

<p>Demographic Information and self-reported data of Participants: Mean (Standard Deviation).</p

Testing mediational effects of bodyweight dissatisfaction within each ROI in Fat-Thin contrast.

<p>Testing mediational effects of bodyweight dissatisfaction within each ROI in Fat-Thin contrast.</p

Porphyrin-Based Porous Organic Frameworks as a Biomimetic Catalyst for Highly Efficient Colorimetric Immunoassay

Herein, we synthesized a cost-effective iron porphyrin (FePor)-based covalent organic polymer (COP), FePor-TFPA-COP, through an easy aromatic substitution reaction between pyrrole and tris­(4-formylphenyl)­amine (TFPA). The triangular pyramid-shaped, N-centric structure of TFPA facilitated the formation of FePor-TFPA-COP with three-dimensional porous structure, larger surface area, and abundant surface catalytically active sites. FePor-TFPA-COP exhibited strong intrinsic peroxidase activity toward a classical peroxidase substrate, 3,3′,5,5′-tetramethylbenzidine (TMB), in the presence of H₂O₂. Compared with horseradish peroxidase (HRP), FePor-TFPA-COP exhibited several advantages such as easy storage, high sensitivity, and prominently chemical and catalytic stability under the harsh conditions, which guaranteed the accuracy and reliability of measurements. Utilizing the excellent catalytic activity, a FePor-TFPA-COP-based colorimetric immunoassay was first established for α-fetoprotein (AFP) detection and showed high sensitivity, stability, and acceptable reproducibility. The linear response range for AFP was 5 pg/mL to 100 ng/mL and the detection limitation was 1 pg/mL. The routine provided a brilliant biomimetic catalyst to develop the nonenzyme immunoassay. More importantly, the high chemical and catalytic stability and sensitivity facilitated future practical applications under various conditions

Nitrogen-Doped Porous Carbon Prepared from Urea Formaldehyde Resins by Template Carbonization Method for Supercapacitors

Through a simple and convenient template carbonization method, nitrogen-doped porous carbon has been successfully achieved by heating urea formaldehyde (UF) resin and magnesium citrate at 800 °C, where the magnesium citrate serves as a template. The mass ratio between the UF resin and magnesium citrate plays a crucial impact on the surface areas, pore structures, and the correlative capacitive behaviors of the final porous carbons, denoted as samples UF-Mg-1:1, -1:3, and -1:5. All present porous carbons exhibited amorphous features with low graphitization degrees. Sample UF-Mg-1:3 displayed the best capacitive performance with a large specific capacitance of 239.7 F g^–1 at a current density of 0.5 A g^–1 and a high energy density of 33.3 Wh kg^–1 at a power density of 0.25 kW kg^–1. More importantly, it exhibited a high capacitance retention of 94.4% after 5000 charge/discharge cycles, clearly indicating good cycling durability

MOESM2 of The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China

Additional file 2: Figure S1. Positive results (iMLSB) in D-test. From left to right are No.10, No.11 and No.17, respectively

Highly Efficient Enzymatic Acylation of Dihydromyricetin by the Immobilized Lipase with Deep Eutectic Solvents as Cosolvent

A novel deep eutectic solvent (DES)–DMSO cosolvent system has been, for the first time, successfully used as the reaction medium for the enzymatic acylation of dihydromyricetin (DMY) catalyzed by the immobilized lipase from <i>Aspergillus niger</i> (ANL). The cosolvent mixture, ChCl:Glycerol–DMSO (1:3, v/v) proved to be the optimal medium. With the newly developed cosolvent, the initial reaction rate of enzymatic acylation of DMY achieved 11.1 mM/h and the conversion of DMY was 91.6%. ANL@PD-MNPs is stable and recyclable in this cosolvent, offering 90% conversion rate after repeated use of 5 times. The lipid-solubility of DMY-16-acetate was 10 times higher than that of its raw materials DMY. The results showed that the DMY-16-acetate product exhibits good antioxidative activity. The present research illustrated that the use of DES–DMSO cosolvent may become a feasible alternative for the synthesis of DMY ester

Meta-analyses of comparative efficacy of antidepressant medications on peripheral BDNF concentration in patients with depression

<div><p>Background</p><p>Brain derived neurotrophic factor (BDNF) is one of the most important regulatory proteins in the pathophysiology of major depressive disorder (MDD). Increasing numbers of studies have reported the relationship between serum/plasma BDNF and antidepressants (ADs). However, the potential effects of several classes of antidepressants on BDNF concentrations are not well known. Hence, our meta-analyses aims to review the effects of differential antidepressant drugs on peripheral BDNF levels in MDD and make some recommendations for future research.</p><p>Methods</p><p>Electronic databases including PubMed, EMBASE, the Cochrane Library, Web of Science, and PsycINFO were searched from 1980 to June 2016. The change in BDNF levels were compared between baseline and post-antidepressants treatment by use of the standardized mean difference (SMD) with 95% confidence intervals (CIs). All statistical tests were two-sided.</p><p>Results</p><p>We identified 20 eligible trials of antidepressants treatments for BDNF in MDD. The overall effect size for all drug classes showed that BDNF levels were elevated following a course of antidepressants use. For between-study heterogeneity by stratification analyses, we detect that length of treatment and blood samples are significant effect modifiers for BDNF levels during antidepressants treatment. While both SSRIs and SNRIs could increase the BDNF levels after a period of antidepressant medication treatment, sertraline was superior to other three drugs (venlafaxine, paroxetine or escitalopram) in the early increase of BDNF concentrations with SMD 0.53(95% CI = 0.13–0.93; <i>P</i> = 0.009).</p><p>Conclusions</p><p>There is some evidence that treatment of antidepressants appears to be effective in the increase of peripheral BDNF levels. More robust evidence indicates that different types of antidepressants appear to induce differential effects on the BDNF levels. Since sertraline makes a particular effect on BDNF concentration within a short amount of time, there is potential value in exploring its relationship with BDNF and its pharmacological mechanism concerning peripheral blood BDNF. Further confirmatory trials are required for both observations.</p></div