Di-μ-benzoato-κ3 O,O′:O′;κ3 O:O,O′-bis[aqua­bis­(benzoato-κ2 O,O′)(dimethylformamide-κO)europium(III)]

The title dimeric complex, [Eu2(C7H5O2)6(C3H7NO)2(H2O)2], is centrosymmetric, implying that pairs of equivalent Eu3+ ions and ligands lie trans to each other and that the two Eu3+ ions have exactly the same coordination environment. Each Eu3+ ion is nine-coordinated by two bidentate benzoate ligands, two bridging tridentate chelating benzoate ligands, and one dimethylformamide and one water molecule. The coordination polyhedron of each Eu3+ ion can be described with a distorted monocapped square-anti­prismatic geometry. The mol­ecular structure is stabilized by intra- and inter­molecular hydrogen bonds between the water mol­ecules and benzoate O atoms

First identification of NDM-4-producing Escherichia coli ST410 in China

Dear Editor, The worldwide dissemination of New Delhi metallo-β-lactamase 1 (NDM-1), an Ambler class B metallo-β-lactamase (MBL) conferring resistance to all β-lactams except monobactams, is of great concern for public health. NDM-4, which differs from NDM-1 by a single amino acid substitution (Met154Leu), was demonstrated to possess increased carbapenemase activity

Emergence of Extensively Drug-Resistant Proteus mirabilis Harboring a Conjugative NDM-1 Plasmid and a Novel Salmonella Genomic Island 1 Variant, SGI1-Z

Acquisition of blaNDM-1 in bacterial species, such as Proteus mirabilis that is intrinsically resistant to tetracycline, tigecycline and colistin, will make clinical treatment extremely difficult. Here, we characterized an NDM-1-producing clinical isolate of P. mirabilis (PM58) that displayed an extensively drug-resistant (XDR) phenotype, susceptible only to aztreonam. Molecular analysis revealed that PM58 harbored both a conjugative NDM-1 plasmid and a novel Salmonella genomic island 1 variant on chromosome

The association of 20 short tandem repeat loci of autosomal chromosome with male schizophrenia

Abstract Introduction Schizophrenia's heritability and familial transmission have been known for several decades. The male‐specific Y chromosome plays an important role in schizophrenia. Short tandem repeats (STRs)have been recognized as risk genes in the development of schizophrenia. Here, we investigated the association between male schizophrenia and Y‐chromosomal STRs loci. Methods We recruited 355 patients with schizophrenia and 473 healthy males for physical examination and amplified them with a PowerPlex 21 System fluorescence‐labeled composite amplification System. Then, the resultant products were separated by electrophoresis and further detected. Finally, differences in allele and genotype frequency distributions of STR loci were observed. Results Our results showed that all 20 STR loci were in accordance with Hardy–Weinberg's law (p > .05). There were statistically significant differences in alleles of D13S317 and D5S818 loci and genotype frequency distribution between the two groups (alleles: p = .039, p = .022, respectively; genotype: p = .0004, p = .011, respectively). However, there was no difference in the other autosomal 18 STR loci between the two groups (p > .05). Univariate analysis showed that the frequency distribution differences of allele 11 and genotype 10‐11 at the D13S317 locus between the two groups were significant (compared to the controls, p = 0.005, odds ratio (OR) = 1.37, 95%b confidence interval (CI) = 1.10–1.71, compared to the controls, p = .0000002, OR = 3.92, 95% CI = 2.27–6.77, respectively). The frequency distribution differences of allele 7 and genotype 7‐10 at D5S818 between the two groups were significant (compared to the controls, p = .0006, OR = 3.42, 95% CI = 1.63–7.16, compared to the controls, p = .0011, OR = 8.24, 95% CI = 1.83–37.05, respectively). Conclusion Polymorphisms of the D13S317 and D5S818 loci may be predisposing factors for schizophrenia