Proportion of HERO staff who expressed a high level of need for the eleven modules.

<p>Proportion of HERO staff who expressed a high level of need for the eleven modules.</p

Selected characteristics of the 1606 health staff who responded to the curriculum development questionnaire.

<p>Note: Not all characteristics of the 1606 respondents at various levels were known.</p

List of competency domains to be considered for inclusion in the curriculum.

<p>List of competency domains to be considered for inclusion in the curriculum.</p

Additional file 1: of Proteomic analysis of protein interactions between Eimeria maxima sporozoites and chicken jejunal epithelial cells by shotgun LC-MS/MS

Table S1. LC-MS/MS analysis of E. maxima sporozoite proteins binding to chicken jejunal epithelial cells. This file describes the details of the 204 non-redundant proteins that were identified using shotgun LC-MS/MS. (XLS 187 kb

Additional file 2: of Proteomic analysis of protein interactions between Eimeria maxima sporozoites and chicken jejunal epithelial cells by shotgun LC-MS/MS

Table S2. Eimeria maxima sporozoite soluble proteins binding to chicken jejunal epithelial cells with more than two unique peptide counts. This file describes the details of the 35 proteins binding to chicken jejunal epithelial cells that were identified with more than two unique peptide counts using shotgun LC-MS/MS. (XLS 95 kb

Additional file 1: Table S1. of Characterization of a novel aspartyl protease inhibitor from Haemonchus contortus

Primers for amplification of API gene. Table S2. Primers for real time PCR. Table S3. Primers for quantification of cytokines transcription. (DOCX 18 kb

DataSheet_1_The quality of life impacting factors in malnourished patients with gastric cancer.docx

IntroductionMalnutrition is prevalent among individuals with gastric cancer and notably decreases their quality of life (QOL). However, the factors impacting QOL are yet to be clearly defined. This study aimed to identify essential factors impacting QOL in malnourished patients suffering from gastric cancer.MethodsBy using the Patient-Generated Subjective Global Assessment (PG-SGA) to assess the nutritional status (≥4 defined malnutrition) of hospitalized cancer patients, 4,586 gastric cancer patients were ultimately defined as malnourished. Spearman method was used to calculate the relationship between clinical features and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Then, univariate and multivariate logistic regression were used to observe which factors affected QOL, and subgroup analysis was performed in young and old population respectively. In addition, we used univariate and multivariate logistic regression to explore whether and how self-reported frequent symptoms in the last 2 weeks of the PG-SGA score affected QOL.ResultsIn multivariate logistic regression analysis of clinical features of patients with malnourished gastric cancer, women, stage II, stage IV, WL had an independent correlation with a low global QOL scores. However, BMI, secondary education, higher education, surgery, chemotherapy, HGS had an independent correlation with a high global QOL scores. In multivariate logistic regression analysis of symptoms in self-reported PG-SGA scores in patients with malnourished gastric cancer, having no problem eating had an independent correlation with a high global QOL scores. However, they have no appetite, nausea, vomiting, constipation and pain had an independent correlation with a lower global QOL scores. The p values of the above statistical results are both ConclusionThis study demonstrates that QOL in malnourished patients with gastric cancer is determined by female sex, stage II, stage IV, BMI, secondary and higher education or above, surgery, chemotherapy, WL, and HGS. Patients’ self-reported symptoms of nearly 2 weeks, obtained by using PG-SGA, are also further predictive of malnourished gastric cancer patients. Detecting preliminary indicators of low QOL could aid in identifying patients who might benefit from an early referral to palliative care and assisted nursing.</p

Additional file 1: of Identification and preliminary characterization of Hc-clec-160, a novel C-type lectin domain-containing gene of the strongylid nematode Haemonchus contortus

Figure S1. Morphology and histology of male (a) and female (b) adults of H. contortus. Panels a and b represent H&E staining of worm paraffin sections at 10×. Scale-bars: 10 mm. (TIF 1691 kb

Additional file 1 of Haemonchus contortus HcL6 promoted the Th9 immune response in goat PBMCs by activating the STAT6/PU.1/NF-κB pathway

Additional file 1: Sequence of the HcL6 gene. The complete coding sequence of the HcL6 gene (567 bp)