Regulation of Nontraditional Intrinsic Luminescence (NTIL) in Hyperbranched Polysiloxanes by Adjusting Alkane Chain Lengths: Mechanism, Film Fabrication, and Chemical Sensing

Biocompatible polymers with nontraditional intrinsic luminescence (NTIL) possess the advantages of environmental friendliness and facile structural regulation. To regulate the emission wavelength of polymers with NTIL, the alkane chain lengths of hyperbranched polysiloxane (HBPSi) are adjusted. Optical investigation shows that the emission wavelength of HBPSi is closely related to the alkane chain lengths; namely, short alkane chains will generate relatively long-wavelength emission. Electronic communication among functional groups is responsible for the emission. In a concentrated solution, HBPSi molecules aggregate together due to the strong hydrogen bond and amphiphilicity, and the functional groups in the aggregate are so close that their electron clouds are overlapped and generate spatial electronic delocalizations. HBPSi with shorter alkane chains will generate larger electronic delocalizations and emit longer-wavelength emissions. Moreover, these polymers show excellent applications in the fabrication of fluorescent films and chemical sensing. This work could provide a strategy for regulating the emission wavelengths of unconventional fluorescent polymers

Image_1_Delipid extracorporeal lipoprotein filter from plasma system: a new intensive lipid lowering therapy for patients with acute ischemic stroke.jpg

ObjectivesTo investigate the safety and efficacy of the delipid extracorporeal lipoprotein filter from plasma (DELP) system, a new low-density lipoprotein cholesterol (LDL-C) adsorption system, in acute ischemic stroke (AIS) patients.Patients and methodsIn the present study, a total of 180 AIS patients were enrolled during March 2019 to February 2021. They were divided into DELP group (n1 = 90) and the control group (n2 = 90). The treatment protocol and vascular access of DELP treatment was established and evaluated. For the DELP group, clinical data and laboratory results including plasma lipid and safety parameters before and after the apheresis were collected and analyzed. For all participants, neurological scores were assessed and recorded.ResultsFor the DELP group, 90 patients including 70 males and 20 females were included. The mean LDL-C was significantly decreased from 3.15 ± 0.80 mmol/L to 2.18 ± 0.63 mmol/L (30.79%, p ConclusionThe new LDL-C adsorption system, the DELP system, may provide a new option for intensive lipid lowering therapy in AIS patients in view of its safety, efficacy, and operation feasibility.</p

Data_Sheet_1_Delipid extracorporeal lipoprotein filter from plasma system: a new intensive lipid lowering therapy for patients with acute ischemic stroke.pdf

ObjectivesTo investigate the safety and efficacy of the delipid extracorporeal lipoprotein filter from plasma (DELP) system, a new low-density lipoprotein cholesterol (LDL-C) adsorption system, in acute ischemic stroke (AIS) patients.Patients and methodsIn the present study, a total of 180 AIS patients were enrolled during March 2019 to February 2021. They were divided into DELP group (n1 = 90) and the control group (n2 = 90). The treatment protocol and vascular access of DELP treatment was established and evaluated. For the DELP group, clinical data and laboratory results including plasma lipid and safety parameters before and after the apheresis were collected and analyzed. For all participants, neurological scores were assessed and recorded.ResultsFor the DELP group, 90 patients including 70 males and 20 females were included. The mean LDL-C was significantly decreased from 3.15 ± 0.80 mmol/L to 2.18 ± 0.63 mmol/L (30.79%, p ConclusionThe new LDL-C adsorption system, the DELP system, may provide a new option for intensive lipid lowering therapy in AIS patients in view of its safety, efficacy, and operation feasibility.</p

NiSi_<i>x</i>/a-Si Nanowires with Interfacial a‑Ge as Anodes for High-Rate Lithium-Ion Batteries

Conductive metal nanowire is a promising current collector for the Si-based anode material in high-rate lithium-ion batteries. However, to harness this remarkable potential for high power density energy storage, one has to address the interfacial potential barrier that hinders the electron injection from the metal side. Herein, we present that, solely by inserting ultrathin amorphous germanium (a-Ge) (∼5 nm) at the interface of NiSi_<i>x</i>/amorphous Si (a-Si), the rate capacity was substantially enhanced, 477 mAh g^–1 even at a high rate of 40 A g^–1. In addition, batteries containing the NiSi_<i>x</i>/Ge+Si anodes cycled over 1000 times at 10 A g^–1 while the capacity retaining more than 877 mAh g^–1, which is among the highest reported. The excellent electrochemical performance is directly correlated with the significantly improved electrical conductivity and mechanical stability throughout the entire electrode. The potential barrier between the NiSi_<i>x</i> and a-Si was modulated by a-Ge, which constructs an electron highway. Besides, the a-Ge interlayer enhances the interfacial adhesion by reducing void fraction and the inhomogeneous strain of the Li–Ge and Li–Si stacking structure was accommodated through the bending and twist of relatively thin NiSi_<i>x</i>, thus ensures a more stable high-rate cycling performance. Our work shows an effective way to fabricate metal/a-Si nanowires for high-rate lithium-ion battery anodes

Giant enhancement of higher-order harmonics of an optical-tweezer phonon laser

Phonon lasers, as mechanical analogues of optical lasers, are unique tools for not only fundamental studies of phononics but also diverse applications such as acoustic imaging and force sensing. Very recently, by levitating a micro-size sphere in an optical tweezer, higher-order mechanical harmonics were observed in the phonon-lasing regime, as the first step towards nonlinear levitated optomechanics [Nat. Phys. 19, 414 (2023)]. However, both the lasing strengths and the quality factors of the observed harmonics are typically very low, thus severely hindering their applications. Here we show that, by applying a simple but powerful electronic control to such a levitated micro-sphere, three orders of magnitude enhancement are achievable in the brightness of the phonon lasers, including both the fundamental mode and all its higher-order harmonics. Also, giant improvements of their linewidth and frequency stability are realized in such an electro-optomechanical system, together with further improved higher-order phonon coherence. These results, as a significant step forward for enhancing and controlling micro-object phonon lasers, can be readily used for a wide range of applications involving nonlinear phonon lasers, such as acoustic frequency comb, ultra-sound sensing, atmospherical monitoring, and even bio-medical diagnosis of levitated micro-size objects

Additional file 1: of Chinese Cervicocephalic artery dissection study (CCADS): rationale and protocol for a multicenter prospective cohort study

CCADS collaborative group. Names of 56 centers participating the study and the corresponding principle investigator in each center. (DOCX 58 kb