Research on Anti-flutter Processing of Aeroengine Casing

Due to the thin and rigid wall of aeroengine casing, it is easy to reduce the machining accuracy for the vibration of machine tools and cutting tools. Therefore, this paper designed an auxiliary fixture that can suppress such vibration. According to the vibration absorption principle of the tuned mass damper, this fixture is designed to transfer the vibration energy of the casing to the auxiliary fixture so as to reduce the vibration of the casing itself. According to Ansy’s work bench analysis, this fixture can significantly reduce the vibration of the casing. The results show that the maximum vibration amplitude of the casing is reduced by 60%, and the average vibration amplitude is also significantly reduced. The auxiliary fixture has many advantages such as simple installation, simple disassembly and installation, strong expansibility and so on

Mechanism and complex roles of HSC70/HSPA8 in viral entry

The process of viruses entering host cells is complex, involving multiple aspects of the molecular organization of the cell membrane, viral proteins, the interaction of receptor molecules, and cellular signaling. Most viruses depend on endocytosis for uptake, when viruses reach the appropriate location, they are released from the vesicles, undergo uncoating, and release their genomes. Heat shock cognate protein 70(HSC70): also known as HSPA8, a protein involved in mediating clathrin-mediated endocytosis (CME), is involved in various viral entry processes. In this mini-review, our goal is to provide a summary of the function of HSC70 in viral entry. Understanding the interaction networks of HSC70 with viral proteins helps to provide new directions for targeted therapeutic strategies against viral infections

Poly(2,5-benzimidazole)-Grafted Graphene Oxide as an Effective Proton Conductor for Construction of Nanocomposite Proton Exchange Membrane

To improve proton conduction properties of conventional sulfonated poly­(ether ether ketone) (SPEEK), poly­(2,5-benzimidazole)-grafted graphene oxide (ABPBI-GO) was prepared to fabricate nanocomposite membranes, which then were further doped with phosphoric acid (PA). The ABPBI-GO was synthesized through the reaction of 3,4-diaminobenzoic acid with the carboxyl acid groups present on the GO surface. The simultaneous incorporation of ABPBI-GO and PA into SPEEK did not only improve the physicochemical performance of the membranes in terms of thermal stability, water uptake, dimensional stability, proton conductivity, and methanol permeation resistance but also relieve PA leaching from the membranes though acid–base interactions. The resulting composite membranes exhibited enhanced proton conductivities in extended humidity ranges thanks to the hygroscopic character of PA and the increased water uptake. Moreover, the unique self-ionization, self-dehydration, and nonvolatile properties of PA improved the high-temperature proton conductivities (σ) of PA-doped membranes. The PA-doped SPEEK/ABPBI-GO-3.0 delivered a σ of 7.5 mS cm^–1 at 140 °C/0% RH. This value was fourfold higher than that of pristine SPEEK membranes. The PA-doped SPEEK/ABPBI-GO-3.0 based fuel cell membranes delivered power densities of 831.06 and 72.25 mW cm^–2 at 80 °C/95% RH and 120 °C/0% RH, respectively. By contrast, the PA-doped SPEEK membrane generated only 655.63 and 44.58 mW cm^–2 under the same testing conditions

Mitigation of Metal Oxide Nanotoxicity with Functional Fibrils

The toxicity of metal oxide nanoparticles has been a central research topic over the past two decades, owing to the domestic and industrial applications of this vast class of nanomaterials [...